Gene List
This API endpoint handles listing (/genes) and retrieval (/genes/<ID>/) of genes that are contained in the database due to their association to
genetic variants that are involved in at least one oligogenic combination in OLIDA.
GET /api/genecombinations/6/genes/?format=api
{ "data": [ { "type": "Gene", "id": "ADD3", "attributes": { "go_molecular_function": [ "actin filament binding", "structural constituent of cytoskeleton", "actin binding" ], "pathway_id": [ "R-HSA-382551", "R-HSA-5223345" ], "essential_gene": "Non-essential", "status": "CU", "uniprot_acc": "Q9UEY8", "ensembl_id": "ENSG00000148700", "entrez_id": "120", "chromosome_number": "10", "lastmodified": "2021-10-18T11:00:44.521990" }, "relationships": { "variant_set": { "meta": { "count": 1 }, "data": [ { "type": "SmallVariant", "id": "13" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/ADD3/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/genes/ADD3/variants/?format=api" } }, "genecombination_set": { "meta": { "count": 1 }, "data": [ { "type": "GeneCombination", "id": "6" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/ADD3/relationships/genecombination_set?format=api", "related": "https://olida.ibsquare.be/api/genes/ADD3/genecombinations/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genes/ADD3/?format=api" } }, { "type": "Gene", "id": "KAT2B", "attributes": { "go_molecular_function": [ "cyclin-dependent protein serine/threonine kinase inhibitor activity", "histone acetyltransferase activity", "protein kinase binding", "protein binding", "transcription coactivator activity", "lysine N-acetyltransferase activity, acting on acetyl phosphate as donor", "acetyltransferase activity", "chromatin binding" ], "pathway_id": [ "R-HSA-210744", "R-HSA-73864", "R-HSA-2644606", "R-HSA-8878171", "R-HSA-2644602", "R-HSA-8939211", "R-HSA-392499", "R-HSA-8941856", "R-HSA-9614085", "R-HSA-2894862", "R-HSA-9012852", "R-HSA-397014", "R-HSA-5250913", "R-HSA-73762", "R-HSA-5688426", "R-HSA-186712", "R-HSA-73857", "R-HSA-8936459", "R-HSA-1980143", "R-HSA-8878159", "R-HSA-597592", "R-HSA-9617629", "R-HSA-73854", "R-HSA-9013508", "R-HSA-3214847", "R-HSA-350054", "R-HSA-5663202", "R-HSA-5689901", "R-HSA-74160", "R-HSA-5578768", "R-HSA-2032785", "R-HSA-2122947", "R-HSA-9013695", "R-HSA-212436", "R-HSA-9006931", "R-HSA-9013694", "R-HSA-1266738", "R-HSA-5576891", "kegg_path:hsa05166", "kegg_path:hsa05203", "R-HSA-3247509", "R-HSA-212165", "kegg_path:hsa04919", "R-HSA-1643685", "R-HSA-9018519", "R-HSA-1912422", "R-HSA-5250924", "R-HSA-157118", "R-HSA-2644603", "R-HSA-2894858", "R-HSA-1912408", "R-HSA-162582", "kegg_path:hsa04330", "R-HSA-4839726" ], "essential_gene": "Non-essential", "status": "CU", "uniprot_acc": "Q92831", "ensembl_id": "ENSG00000114166", "entrez_id": "8850", "chromosome_number": "3", "lastmodified": "2021-10-18T11:00:44.840805" }, "relationships": { "variant_set": { "meta": { "count": 1 }, "data": [ { "type": "SmallVariant", "id": "14" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/KAT2B/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/genes/KAT2B/variants/?format=api" } }, "genecombination_set": { "meta": { "count": 1 }, "data": [ { "type": "GeneCombination", "id": "6" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/KAT2B/relationships/genecombination_set?format=api", "related": "https://olida.ibsquare.be/api/genes/KAT2B/genecombinations/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genes/KAT2B/?format=api" } } ], "meta": { "database_name": "OLIgogenic diseases DAtabase (OLIDA)", "resource_url": "olida.ibsquare.be", "api_release_year": "2021", "api_developer": [ [ "Arnau Dillen", "arnau.dillen@ulb.ac.be" ], [ "Charlotte Nachtegael", "charlotte.nachtegael@ulb.be" ] ], "api_version": "0.3", "api_maintainers": [ [ "Charlotte Nachtegael", "charlotte.nachtegael@ulb.be" ] ], "api_documentation": [ "olida.ibsquare.be/api/swagger", "olida.ibsquare.be/api/redoc" ], "copyright": "Copyright (c) 2025 · OLIDA All Rights Reserved.", "license": "CC Attribution-NonCommercial 4.0 International License", "ontologies": { "ORDO": "http://bioportal.bioontology.org/ontologies/ORDO", "GENO": "http://purl.obolibrary.org/obo/geno.owl", "MI": "http://purl.obolibrary.org/obo/mi.owl", "NCIT": "http://purl.obolibrary.org/obo/ncit.owl", "OGI": "http://purl.obolibrary.org/obo/ogi.owl", "OGG": "http://purl.obolibrary.org/obo/ogg.owl" }, "relevant_publications_doi": [ "10.1093/nar/gkv1068", "10.1093/database/baac023" ], "size": 2 } }