Gene List
This API endpoint handles listing (/genes) and retrieval (/genes/<ID>/) of genes that are contained in the database due to their association to
genetic variants that are involved in at least one oligogenic combination in OLIDA.
GET /api/genecombinations/598/genes/?format=api
{ "data": [ { "type": "Gene", "id": "CCNF", "attributes": { "go_molecular_function": [ "cyclin-dependent protein serine/threonine kinase regulator activity", "anaphase-promoting complex binding", "protein binding" ], "pathway_id": [ "R-HSA-8951664", "R-HSA-983169", "R-HSA-168256", "R-HSA-983168", "R-HSA-597592", "R-HSA-1280218", "R-HSA-392499" ], "essential_gene": "Essential", "status": "CU", "uniprot_acc": "P41002", "ensembl_id": "ENSG00000162063", "entrez_id": "899", "chromosome_number": "16", "lastmodified": "2021-10-18T11:00:44.271750" }, "relationships": { "variant_set": { "meta": { "count": 4 }, "data": [ { "type": "SmallVariant", "id": "1380" }, { "type": "SmallVariant", "id": "1811" }, { "type": "SmallVariant", "id": "2059" }, { "type": "SmallVariant", "id": "2192" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/CCNF/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/genes/CCNF/variants/?format=api" } }, "genecombination_set": { "meta": { "count": 4 }, "data": [ { "type": "GeneCombination", "id": "434" }, { "type": "GeneCombination", "id": "598" }, { "type": "GeneCombination", "id": "710" }, { "type": "GeneCombination", "id": "748" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/CCNF/relationships/genecombination_set?format=api", "related": "https://olida.ibsquare.be/api/genes/CCNF/genecombinations/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genes/CCNF/?format=api" } }, { "type": "Gene", "id": "KIF5A", "attributes": { "go_molecular_function": [ "kinesin binding", "protein binding", "ATP hydrolysis activity", "microtubule binding", "microtubule motor activity", "plus-end-directed microtubule motor activity", "ATP binding", "cytoskeletal motor activity" ], "pathway_id": [ "kegg_path:hsa05012", "kegg_path:hsa05010", "kegg_path:hsa05020", "R-HSA-5625970", "R-HSA-109582", "R-HSA-5653656", "R-HSA-6811442", "kegg_path:hsa04144", "R-HSA-8856688", "R-HSA-1280218", "R-HSA-2980736", "R-HSA-392499", "kegg_path:hsa05223", "kegg_path:hsa05014", "R-HSA-168256", "R-HSA-983189", "R-HSA-162582", "kegg_path:hsa05016", "R-HSA-264876", "R-HSA-194315", "R-HSA-6811434", "R-HSA-2132295", "kegg_path:hsa05132", "R-HSA-199991", "kegg_path:hsa04728", "R-HSA-983231", "kegg_path:hsa05022", "R-HSA-195258" ], "essential_gene": "Essential", "status": "CU", "uniprot_acc": "Q12840", "ensembl_id": "ENSG00000155980", "entrez_id": "3798", "chromosome_number": "12", "lastmodified": "2021-10-18T11:00:44.964917" }, "relationships": { "variant_set": { "meta": { "count": 2 }, "data": [ { "type": "SmallVariant", "id": "1812" }, { "type": "SmallVariant", "id": "2068" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/KIF5A/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/genes/KIF5A/variants/?format=api" } }, "genecombination_set": { "meta": { "count": 2 }, "data": [ { "type": "GeneCombination", "id": "598" }, { "type": "GeneCombination", "id": "714" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/KIF5A/relationships/genecombination_set?format=api", "related": "https://olida.ibsquare.be/api/genes/KIF5A/genecombinations/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genes/KIF5A/?format=api" } } ], "meta": { "database_name": "OLIgogenic diseases DAtabase (OLIDA)", "resource_url": "olida.ibsquare.be", "api_release_year": "2021", "api_developer": [ [ "Arnau Dillen", "arnau.dillen@ulb.ac.be" ], [ "Charlotte Nachtegael", "charlotte.nachtegael@ulb.be" ] ], "api_version": "0.3", "api_maintainers": [ [ "Charlotte Nachtegael", "charlotte.nachtegael@ulb.be" ] ], "api_documentation": [ "olida.ibsquare.be/api/swagger", "olida.ibsquare.be/api/redoc" ], "copyright": "Copyright (c) 2025 · OLIDA All Rights Reserved.", "license": "CC Attribution-NonCommercial 4.0 International License", "ontologies": { "ORDO": "http://bioportal.bioontology.org/ontologies/ORDO", "GENO": "http://purl.obolibrary.org/obo/geno.owl", "MI": "http://purl.obolibrary.org/obo/mi.owl", "NCIT": "http://purl.obolibrary.org/obo/ncit.owl", "OGI": "http://purl.obolibrary.org/obo/ogi.owl", "OGG": "http://purl.obolibrary.org/obo/ogg.owl" }, "relevant_publications_doi": [ "10.1093/nar/gkv1068", "10.1093/database/baac023" ], "size": 2 } }