Gene List
This API endpoint handles listing (/genes) and retrieval (/genes/<ID>/) of genes that are contained in the database due to their association to
genetic variants that are involved in at least one oligogenic combination in OLIDA.
GET /api/genecombinations/593/genes/?format=api
{ "data": [ { "type": "Gene", "id": "KL", "attributes": { "go_molecular_function": [ "['beta-glucuronidase activity', 'fibroblast growth factor binding', 'hormone activity', 'beta-glucosidase activity', 'fibroblast growth factor receptor binding', 'vitamin D binding']" ], "pathway_id": [ "kegg_path:hsa00040", "kegg_path:hsa00053", "kegg_path:hsa01100", "kegg_path:hsa04211", "kegg_path:hsa04928", "kegg_path:hsa04961" ], "essential_gene": "Non-essential", "status": "CU", "uniprot_acc": "Q9UEF7", "ensembl_id": "None", "entrez_id": "ENSG00000133116", "chromosome_number": "13", "lastmodified": "2021-10-18T11:00:44.898359" }, "relationships": { "variant_set": { "meta": { "count": 3 }, "data": [ { "type": "SmallVariant", "id": "1791" }, { "type": "SmallVariant", "id": "2900" }, { "type": "SmallVariant", "id": "2944" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/KL/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/genes/KL/variants/?format=api" } }, "genecombination_set": { "meta": { "count": 3 }, "data": [ { "type": "GeneCombination", "id": "593" }, { "type": "GeneCombination", "id": "961" }, { "type": "GeneCombination", "id": "979" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/KL/relationships/genecombination_set?format=api", "related": "https://olida.ibsquare.be/api/genes/KL/genecombinations/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genes/KL/?format=api" } }, { "type": "Gene", "id": "POLR3A", "attributes": { "go_molecular_function": [ "['DNA binding', 'chromatin binding', 'metal ion binding', \"DNA-directed 5'-3' RNA polymerase activity\"]" ], "pathway_id": [ "kegg_path:hsa03020", "kegg_path:hsa04623", "R-HSA-168249", "R-HSA-168256", "R-HSA-1834949", "R-HSA-73780", "R-HSA-73980", "R-HSA-74158", "R-HSA-74160", "R-HSA-749476", "R-HSA-76046", "R-HSA-76061", "R-HSA-76066", "R-HSA-76071" ], "essential_gene": null, "status": "CU", "uniprot_acc": "O14802", "ensembl_id": "None", "entrez_id": "ENSG00000148606", "chromosome_number": "10", "lastmodified": "2021-10-18T11:00:44.815827" }, "relationships": { "variant_set": { "meta": { "count": 6 }, "data": [ { "type": "SmallVariant", "id": "38" }, { "type": "SmallVariant", "id": "1422" }, { "type": "SmallVariant", "id": "1792" }, { "type": "SmallVariant", "id": "1854" }, { "type": "SmallVariant", "id": "2781" }, { "type": "SmallVariant", "id": "2888" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/POLR3A/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/genes/POLR3A/variants/?format=api" } }, "genecombination_set": { "meta": { "count": 6 }, "data": [ { "type": "GeneCombination", "id": "15" }, { "type": "GeneCombination", "id": "447" }, { "type": "GeneCombination", "id": "593" }, { "type": "GeneCombination", "id": "616" }, { "type": "GeneCombination", "id": "930" }, { "type": "GeneCombination", "id": "956" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/POLR3A/relationships/genecombination_set?format=api", "related": "https://olida.ibsquare.be/api/genes/POLR3A/genecombinations/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genes/POLR3A/?format=api" } } ], "meta": { "database_name": "OLIgogenic diseases DAtabase (OLIDA)", "resource_url": "olida.ibsquare.be", "api_release_year": "2021", "api_developer": [ [ "Arnau Dillen", "arnau.dillen@ulb.ac.be" ], [ "Charlotte Nachtegael", "charlotte.nachtegael@ulb.be" ] ], "api_version": "0.3", "api_maintainers": [ [ "Charlotte Nachtegael", "charlotte.nachtegael@ulb.be" ] ], "api_documentation": [ "olida.ibsquare.be/api/swagger", "olida.ibsquare.be/api/redoc" ], "copyright": "Copyright (c) 2025 · OLIDA All Rights Reserved.", "license": "CC Attribution-NonCommercial 4.0 International License", "ontologies": { "ORDO": "http://bioportal.bioontology.org/ontologies/ORDO", "GENO": "http://purl.obolibrary.org/obo/geno.owl", "MI": "http://purl.obolibrary.org/obo/mi.owl", "NCIT": "http://purl.obolibrary.org/obo/ncit.owl", "OGI": "http://purl.obolibrary.org/obo/ogi.owl", "OGG": "http://purl.obolibrary.org/obo/ogg.owl" }, "relevant_publications_doi": [ "10.1093/nar/gkv1068", "10.1093/database/baac023" ], "size": 2 } }