Gene List
This API endpoint handles listing (/genes) and retrieval (/genes/<ID>/) of genes that are contained in the database due to their association to
genetic variants that are involved in at least one oligogenic combination in OLIDA.
GET /api/genecombinations/592/genes/?format=api
{ "data": [ { "type": "Gene", "id": "NUBPL", "attributes": { "go_molecular_function": [ "protein binding", "4 iron, 4 sulfur cluster binding", "ATP hydrolysis activity", "ATP binding", "nucleotide binding", "iron-sulfur cluster binding", "metal ion binding" ], "pathway_id": [ "R-HSA-6799198", "R-HSA-611105", "R-HSA-1428517", "R-HSA-163200", "R-HSA-1430728" ], "essential_gene": null, "status": "CU", "uniprot_acc": "Q8TB37", "ensembl_id": "ENSG00000151413", "entrez_id": "80224", "chromosome_number": "14", "lastmodified": "2021-10-18T11:00:44.913367" }, "relationships": { "variant_set": { "meta": { "count": 1 }, "data": [ { "type": "SmallVariant", "id": "1789" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/NUBPL/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/genes/NUBPL/variants/?format=api" } }, "genecombination_set": { "meta": { "count": 1 }, "data": [ { "type": "GeneCombination", "id": "592" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/NUBPL/relationships/genecombination_set?format=api", "related": "https://olida.ibsquare.be/api/genes/NUBPL/genecombinations/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genes/NUBPL/?format=api" } }, { "type": "Gene", "id": "OAT", "attributes": { "go_molecular_function": [ "pyridoxal phosphate binding", "protein binding", "transferase activity", "catalytic activity", "transaminase activity", "ornithine-oxo-acid transaminase activity", "ornithine(lysine) transaminase activity", "identical protein binding" ], "pathway_id": [ "R-HSA-1430728", "kegg_path:hsa01100", "R-HSA-71291", "R-HSA-8964539", "kegg_path:hsa00330" ], "essential_gene": "Essential", "status": "CU", "uniprot_acc": "P04181", "ensembl_id": "ENSG00000065154", "entrez_id": "4942", "chromosome_number": "10", "lastmodified": "2021-10-18T11:00:44.388368" }, "relationships": { "variant_set": { "meta": { "count": 1 }, "data": [ { "type": "SmallVariant", "id": "1790" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/OAT/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/genes/OAT/variants/?format=api" } }, "genecombination_set": { "meta": { "count": 1 }, "data": [ { "type": "GeneCombination", "id": "592" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/OAT/relationships/genecombination_set?format=api", "related": "https://olida.ibsquare.be/api/genes/OAT/genecombinations/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genes/OAT/?format=api" } } ], "meta": { "database_name": "OLIgogenic diseases DAtabase (OLIDA)", "resource_url": "olida.ibsquare.be", "api_release_year": "2021", "api_developer": [ [ "Arnau Dillen", "arnau.dillen@ulb.ac.be" ], [ "Charlotte Nachtegael", "charlotte.nachtegael@ulb.be" ] ], "api_version": "0.3", "api_maintainers": [ [ "Charlotte Nachtegael", "charlotte.nachtegael@ulb.be" ] ], "api_documentation": [ "olida.ibsquare.be/api/swagger", "olida.ibsquare.be/api/redoc" ], "copyright": "Copyright (c) 2025 · OLIDA All Rights Reserved.", "license": "CC Attribution-NonCommercial 4.0 International License", "ontologies": { "ORDO": "http://bioportal.bioontology.org/ontologies/ORDO", "GENO": "http://purl.obolibrary.org/obo/geno.owl", "MI": "http://purl.obolibrary.org/obo/mi.owl", "NCIT": "http://purl.obolibrary.org/obo/ncit.owl", "OGI": "http://purl.obolibrary.org/obo/ogi.owl", "OGG": "http://purl.obolibrary.org/obo/ogg.owl" }, "relevant_publications_doi": [ "10.1093/nar/gkv1068", "10.1093/database/baac023" ], "size": 2 } }