Gene List
This API endpoint handles listing (/genes) and retrieval (/genes/<ID>/) of genes that are contained in the database due to their association to
genetic variants that are involved in at least one oligogenic combination in OLIDA.
GET /api/genecombinations/590/genes/?format=api
{ "data": [ { "type": "Gene", "id": "CPT2", "attributes": { "go_molecular_function": [ "carnitine O-octanoyltransferase activity", "protein binding", "carnitine O-palmitoyltransferase activity" ], "pathway_id": [ "kegg_path:hsa03320", "kegg_path:hsa04714", "R-HSA-556833", "kegg_path:hsa01212", "R-HSA-1430728", "R-HSA-1989781", "R-HSA-400206", "R-HSA-200425", "kegg_path:hsa00071", "R-HSA-8978868" ], "essential_gene": null, "status": "CU", "uniprot_acc": "P23786", "ensembl_id": "ENSG00000157184", "entrez_id": "1376", "chromosome_number": "1", "lastmodified": "2021-10-18T11:00:44.886458" }, "relationships": { "variant_set": { "meta": { "count": 3 }, "data": [ { "type": "SmallVariant", "id": "431" }, { "type": "SmallVariant", "id": "981" }, { "type": "SmallVariant", "id": "1785" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/CPT2/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/genes/CPT2/variants/?format=api" } }, "genecombination_set": { "meta": { "count": 3 }, "data": [ { "type": "GeneCombination", "id": "145" }, { "type": "GeneCombination", "id": "315" }, { "type": "GeneCombination", "id": "590" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/CPT2/relationships/genecombination_set?format=api", "related": "https://olida.ibsquare.be/api/genes/CPT2/genecombinations/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genes/CPT2/?format=api" } }, { "type": "Gene", "id": "ELAC2", "attributes": { "go_molecular_function": [ "tRNA-specific ribonuclease activity", "nuclease activity", "endonuclease activity", "hydrolase activity", "endoribonuclease activity", "3'-tRNA processing endoribonuclease activity", "metal ion binding" ], "pathway_id": [ "R-HSA-6785470", "kegg_path:hsa03013", "R-HSA-6784531", "kegg_path:hsa03013", "R-HSA-8868766", "R-HSA-72312", "R-HSA-72306", "R-HSA-8953854" ], "essential_gene": null, "status": "CU", "uniprot_acc": "Q9BQ52", "ensembl_id": "ENSG00000006744", "entrez_id": "60528", "chromosome_number": "17", "lastmodified": "2021-10-18T11:00:44.268118" }, "relationships": { "variant_set": { "meta": { "count": 1 }, "data": [ { "type": "SmallVariant", "id": "1786" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/ELAC2/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/genes/ELAC2/variants/?format=api" } }, "genecombination_set": { "meta": { "count": 1 }, "data": [ { "type": "GeneCombination", "id": "590" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/ELAC2/relationships/genecombination_set?format=api", "related": "https://olida.ibsquare.be/api/genes/ELAC2/genecombinations/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genes/ELAC2/?format=api" } } ], "meta": { "database_name": "OLIgogenic diseases DAtabase (OLIDA)", "resource_url": "olida.ibsquare.be", "api_release_year": "2021", "api_developer": [ [ "Arnau Dillen", "arnau.dillen@ulb.ac.be" ], [ "Charlotte Nachtegael", "charlotte.nachtegael@ulb.be" ] ], "api_version": "0.3", "api_maintainers": [ [ "Charlotte Nachtegael", "charlotte.nachtegael@ulb.be" ] ], "api_documentation": [ "olida.ibsquare.be/api/swagger", "olida.ibsquare.be/api/redoc" ], "copyright": "Copyright (c) 2025 · OLIDA All Rights Reserved.", "license": "CC Attribution-NonCommercial 4.0 International License", "ontologies": { "ORDO": "http://bioportal.bioontology.org/ontologies/ORDO", "GENO": "http://purl.obolibrary.org/obo/geno.owl", "MI": "http://purl.obolibrary.org/obo/mi.owl", "NCIT": "http://purl.obolibrary.org/obo/ncit.owl", "OGI": "http://purl.obolibrary.org/obo/ogi.owl", "OGG": "http://purl.obolibrary.org/obo/ogg.owl" }, "relevant_publications_doi": [ "10.1093/nar/gkv1068", "10.1093/database/baac023" ], "size": 2 } }