Gene List
This API endpoint handles listing (/genes) and retrieval (/genes/<ID>/) of genes that are contained in the database due to their association to
genetic variants that are involved in at least one oligogenic combination in OLIDA.
GET /api/genecombinations/588/genes/?format=api
{ "data": [ { "type": "Gene", "id": "GBE1", "attributes": { "go_molecular_function": [ "carbohydrate binding", "1,4-alpha-glucan branching enzyme activity (using a glucosylated glycogenin as primer for glycogen synthesis)", "1,4-alpha-glucan branching enzyme activity", "protein binding" ], "pathway_id": [ "R-HSA-71387", "R-HSA-1430728", "R-HSA-3322077", "kegg_path:hsa01100", "R-HSA-5663084", "R-HSA-3878781", "R-HSA-1643685", "R-HSA-8982491", "kegg_path:hsa00500", "R-HSA-3229121", "R-HSA-5668914" ], "essential_gene": "Essential", "status": "CU", "uniprot_acc": "Q04446", "ensembl_id": "ENSG00000114480", "entrez_id": "2632", "chromosome_number": "3", "lastmodified": "2021-10-18T11:00:44.529170" }, "relationships": { "variant_set": { "meta": { "count": 3 }, "data": [ { "type": "SmallVariant", "id": "1738" }, { "type": "SmallVariant", "id": "1776" }, { "type": "SmallVariant", "id": "1779" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/GBE1/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/genes/GBE1/variants/?format=api" } }, "genecombination_set": { "meta": { "count": 3 }, "data": [ { "type": "GeneCombination", "id": "573" }, { "type": "GeneCombination", "id": "587" }, { "type": "GeneCombination", "id": "588" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/GBE1/relationships/genecombination_set?format=api", "related": "https://olida.ibsquare.be/api/genes/GBE1/genecombinations/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genes/GBE1/?format=api" } }, { "type": "Gene", "id": "PCCB", "attributes": { "go_molecular_function": [ "propionyl-CoA carboxylase activity", "protein binding", "ATP binding", "nucleotide binding", "ligase activity" ], "pathway_id": [ "kegg_path:hsa00280", "R-HSA-3371599", "R-HSA-196780", "R-HSA-77289", "R-HSA-3296482", "kegg_path:hsa01100", "R-HSA-556833", "kegg_path:hsa00640", "R-HSA-196854", "kegg_path:hsa00630", "R-HSA-3323169", "R-HSA-1643685", "R-HSA-196849", "R-HSA-8978868", "kegg_path:hsa01200", "R-HSA-5668914", "R-HSA-71032", "R-HSA-1430728" ], "essential_gene": null, "status": "CU", "uniprot_acc": "P05166", "ensembl_id": "ENSG00000114054", "entrez_id": "5096", "chromosome_number": "3", "lastmodified": "2021-10-18T11:00:44.810173" }, "relationships": { "variant_set": { "meta": { "count": 1 }, "data": [ { "type": "SmallVariant", "id": "1780" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/PCCB/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/genes/PCCB/variants/?format=api" } }, "genecombination_set": { "meta": { "count": 1 }, "data": [ { "type": "GeneCombination", "id": "588" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/PCCB/relationships/genecombination_set?format=api", "related": "https://olida.ibsquare.be/api/genes/PCCB/genecombinations/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genes/PCCB/?format=api" } } ], "meta": { "database_name": "OLIgogenic diseases DAtabase (OLIDA)", "resource_url": "olida.ibsquare.be", "api_release_year": "2021", "api_developer": [ [ "Arnau Dillen", "arnau.dillen@ulb.ac.be" ], [ "Charlotte Nachtegael", "charlotte.nachtegael@ulb.be" ] ], "api_version": "0.3", "api_maintainers": [ [ "Charlotte Nachtegael", "charlotte.nachtegael@ulb.be" ] ], "api_documentation": [ "olida.ibsquare.be/api/swagger", "olida.ibsquare.be/api/redoc" ], "copyright": "Copyright (c) 2024 · OLIDA All Rights Reserved.", "license": "CC Attribution-NonCommercial 4.0 International License", "ontologies": { "ORDO": "http://bioportal.bioontology.org/ontologies/ORDO", "GENO": "http://purl.obolibrary.org/obo/geno.owl", "MI": "http://purl.obolibrary.org/obo/mi.owl", "NCIT": "http://purl.obolibrary.org/obo/ncit.owl", "OGI": "http://purl.obolibrary.org/obo/ogi.owl", "OGG": "http://purl.obolibrary.org/obo/ogg.owl" }, "relevant_publications_doi": [ "10.1093/nar/gkv1068", "10.1093/database/baac023" ], "size": 2 } }