Gene List
This API endpoint handles listing (/genes) and retrieval (/genes/<ID>/) of genes that are contained in the database due to their association to
genetic variants that are involved in at least one oligogenic combination in OLIDA.
GET /api/genecombinations/584/genes/?format=api
{ "data": [ { "type": "Gene", "id": "SCNN1B", "attributes": { "go_molecular_function": [ "WW domain binding", "protein binding", "ligand-gated sodium channel activity" ], "pathway_id": [ "kegg_path:hsa04960", "kegg_path:hsa04742", "R-HSA-382551", "R-HSA-983712", "R-HSA-2672351", "kegg_path:hsa04742", "kegg_path:hsa04960" ], "essential_gene": "Essential", "status": "CU", "uniprot_acc": "P51168", "ensembl_id": "ENSG00000168447", "entrez_id": "6338", "chromosome_number": "16", "lastmodified": "2021-10-18T11:00:44.385296" }, "relationships": { "variant_set": { "meta": { "count": 2 }, "data": [ { "type": "SmallVariant", "id": "1768" }, { "type": "SmallVariant", "id": "1771" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/SCNN1B/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/genes/SCNN1B/variants/?format=api" } }, "genecombination_set": { "meta": { "count": 2 }, "data": [ { "type": "GeneCombination", "id": "584" }, { "type": "GeneCombination", "id": "585" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/SCNN1B/relationships/genecombination_set?format=api", "related": "https://olida.ibsquare.be/api/genes/SCNN1B/genecombinations/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genes/SCNN1B/?format=api" } }, { "type": "Gene", "id": "SCNN1G", "attributes": { "go_molecular_function": [ "ligand-gated sodium channel activity", "protein binding", "sodium channel activity" ], "pathway_id": [ "kegg_path:hsa04960", "R-HSA-2672351", "kegg_path:hsa04742", "R-HSA-983712", "R-HSA-382551", "kegg_path:hsa04742", "kegg_path:hsa04960" ], "essential_gene": "Essential", "status": "CU", "uniprot_acc": "P51170", "ensembl_id": "ENSG00000166828", "entrez_id": "6340", "chromosome_number": "16", "lastmodified": "2021-10-18T11:00:44.262593" }, "relationships": { "variant_set": { "meta": { "count": 1 }, "data": [ { "type": "SmallVariant", "id": "1765" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/SCNN1G/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/genes/SCNN1G/variants/?format=api" } }, "genecombination_set": { "meta": { "count": 2 }, "data": [ { "type": "GeneCombination", "id": "582" }, { "type": "GeneCombination", "id": "584" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/SCNN1G/relationships/genecombination_set?format=api", "related": "https://olida.ibsquare.be/api/genes/SCNN1G/genecombinations/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genes/SCNN1G/?format=api" } }, { "type": "Gene", "id": "SERPINA1", "attributes": { "go_molecular_function": [ "protein binding", "serine-type endopeptidase inhibitor activity", "identical protein binding" ], "pathway_id": [ "R-HSA-199977", "R-HSA-597592", "R-HSA-381426", "R-HSA-168249", "R-HSA-392499", "R-HSA-114608", "R-HSA-5653656", "R-HSA-6798695", "R-HSA-204005", "R-HSA-109582", "R-HSA-199991", "R-HSA-76005", "R-HSA-948021", "R-HSA-76002", "R-HSA-8957275", "kegg_path:hsa04610", "kegg_path:hsa04610", "R-HSA-446203", "R-HSA-5694530", "R-HSA-168256" ], "essential_gene": null, "status": "CU", "uniprot_acc": "P01009", "ensembl_id": "ENSG00000197249", "entrez_id": "5265", "chromosome_number": "14", "lastmodified": "2021-10-18T11:00:44.259449" }, "relationships": { "variant_set": { "meta": { "count": 2 }, "data": [ { "type": "SmallVariant", "id": "1762" }, { "type": "SmallVariant", "id": "1769" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/SERPINA1/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/genes/SERPINA1/variants/?format=api" } }, "genecombination_set": { "meta": { "count": 3 }, "data": [ { "type": "GeneCombination", "id": "581" }, { "type": "GeneCombination", "id": "583" }, { "type": "GeneCombination", "id": "584" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/SERPINA1/relationships/genecombination_set?format=api", "related": "https://olida.ibsquare.be/api/genes/SERPINA1/genecombinations/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genes/SERPINA1/?format=api" } } ], "meta": { "database_name": "OLIgogenic diseases DAtabase (OLIDA)", "resource_url": "olida.ibsquare.be", "api_release_year": "2021", "api_developer": [ [ "Arnau Dillen", "arnau.dillen@ulb.ac.be" ], [ "Charlotte Nachtegael", "charlotte.nachtegael@ulb.be" ] ], "api_version": "0.3", "api_maintainers": [ [ "Charlotte Nachtegael", "charlotte.nachtegael@ulb.be" ] ], "api_documentation": [ "olida.ibsquare.be/api/swagger", "olida.ibsquare.be/api/redoc" ], "copyright": "Copyright (c) 2025 · OLIDA All Rights Reserved.", "license": "CC Attribution-NonCommercial 4.0 International License", "ontologies": { "ORDO": "http://bioportal.bioontology.org/ontologies/ORDO", "GENO": "http://purl.obolibrary.org/obo/geno.owl", "MI": "http://purl.obolibrary.org/obo/mi.owl", "NCIT": "http://purl.obolibrary.org/obo/ncit.owl", "OGI": "http://purl.obolibrary.org/obo/ogi.owl", "OGG": "http://purl.obolibrary.org/obo/ogg.owl" }, "relevant_publications_doi": [ "10.1093/nar/gkv1068", "10.1093/database/baac023" ], "size": 3 } }