Gene List
This API endpoint handles listing (/genes) and retrieval (/genes/<ID>/) of genes that are contained in the database due to their association to
genetic variants that are involved in at least one oligogenic combination in OLIDA.
GET /api/genecombinations/578/genes/?format=api
{ "data": [ { "type": "Gene", "id": "BRWD3", "attributes": { "go_molecular_function": [], "pathway_id": [], "essential_gene": "Non-essential", "status": "CU", "uniprot_acc": "Q6RI45", "ensembl_id": "ENSG00000165288", "entrez_id": "254065", "chromosome_number": "X", "lastmodified": "2021-10-18T11:00:44.976965" }, "relationships": { "variant_set": { "meta": { "count": 1 }, "data": [ { "type": "SmallVariant", "id": "1753" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/BRWD3/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/genes/BRWD3/variants/?format=api" } }, "genecombination_set": { "meta": { "count": 1 }, "data": [ { "type": "GeneCombination", "id": "578" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/BRWD3/relationships/genecombination_set?format=api", "related": "https://olida.ibsquare.be/api/genes/BRWD3/genecombinations/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genes/BRWD3/?format=api" } }, { "type": "Gene", "id": "DRG1", "attributes": { "go_molecular_function": [ "protein binding", "nucleotide binding", "hydrolase activity", "transcription factor binding", "GTP binding", "metal ion binding", "identical protein binding" ], "pathway_id": [], "essential_gene": null, "status": "CU", "uniprot_acc": "Q9Y295", "ensembl_id": "ENSG00000185721", "entrez_id": "4733", "chromosome_number": "22", "lastmodified": "2021-10-18T11:00:44.322645" }, "relationships": { "variant_set": { "meta": { "count": 1 }, "data": [ { "type": "SmallVariant", "id": "1752" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/DRG1/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/genes/DRG1/variants/?format=api" } }, "genecombination_set": { "meta": { "count": 1 }, "data": [ { "type": "GeneCombination", "id": "578" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/DRG1/relationships/genecombination_set?format=api", "related": "https://olida.ibsquare.be/api/genes/DRG1/genecombinations/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genes/DRG1/?format=api" } }, { "type": "Gene", "id": "TANC1", "attributes": { "go_molecular_function": [ "protein binding" ], "pathway_id": [], "essential_gene": "Non-essential", "status": "CU", "uniprot_acc": "Q9C0D5", "ensembl_id": "ENSG00000115183", "entrez_id": "85461", "chromosome_number": "2", "lastmodified": "2021-10-18T11:00:44.636359" }, "relationships": { "variant_set": { "meta": { "count": 1 }, "data": [ { "type": "SmallVariant", "id": "1754" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/TANC1/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/genes/TANC1/variants/?format=api" } }, "genecombination_set": { "meta": { "count": 1 }, "data": [ { "type": "GeneCombination", "id": "578" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/TANC1/relationships/genecombination_set?format=api", "related": "https://olida.ibsquare.be/api/genes/TANC1/genecombinations/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genes/TANC1/?format=api" } } ], "meta": { "database_name": "OLIgogenic diseases DAtabase (OLIDA)", "resource_url": "olida.ibsquare.be", "api_release_year": "2021", "api_developer": [ [ "Arnau Dillen", "arnau.dillen@ulb.ac.be" ], [ "Charlotte Nachtegael", "charlotte.nachtegael@ulb.be" ] ], "api_version": "0.3", "api_maintainers": [ [ "Charlotte Nachtegael", "charlotte.nachtegael@ulb.be" ] ], "api_documentation": [ "olida.ibsquare.be/api/swagger", "olida.ibsquare.be/api/redoc" ], "copyright": "Copyright (c) 2025 · OLIDA All Rights Reserved.", "license": "CC Attribution-NonCommercial 4.0 International License", "ontologies": { "ORDO": "http://bioportal.bioontology.org/ontologies/ORDO", "GENO": "http://purl.obolibrary.org/obo/geno.owl", "MI": "http://purl.obolibrary.org/obo/mi.owl", "NCIT": "http://purl.obolibrary.org/obo/ncit.owl", "OGI": "http://purl.obolibrary.org/obo/ogi.owl", "OGG": "http://purl.obolibrary.org/obo/ogg.owl" }, "relevant_publications_doi": [ "10.1093/nar/gkv1068", "10.1093/database/baac023" ], "size": 3 } }