Gene List
This API endpoint handles listing (/genes) and retrieval (/genes/<ID>/) of genes that are contained in the database due to their association to
genetic variants that are involved in at least one oligogenic combination in OLIDA.
GET /api/genecombinations/577/genes/?format=api
{ "data": [ { "type": "Gene", "id": "HOXA11", "attributes": { "go_molecular_function": [ "sequence-specific double-stranded DNA binding", "DNA-binding transcription factor activity, RNA polymerase II-specific", "DNA binding", "RNA polymerase II cis-regulatory region sequence-specific DNA binding" ], "pathway_id": [ "kegg_path:hsa05202" ], "essential_gene": "Non-essential", "status": "CU", "uniprot_acc": "P31270", "ensembl_id": "ENSG00000005073", "entrez_id": "3207", "chromosome_number": "7", "lastmodified": "2021-10-18T11:00:44.228050" }, "relationships": { "variant_set": { "meta": { "count": 1 }, "data": [ { "type": "SmallVariant", "id": "1750" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/HOXA11/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/genes/HOXA11/variants/?format=api" } }, "genecombination_set": { "meta": { "count": 1 }, "data": [ { "type": "GeneCombination", "id": "577" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/HOXA11/relationships/genecombination_set?format=api", "related": "https://olida.ibsquare.be/api/genes/HOXA11/genecombinations/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genes/HOXA11/?format=api" } }, { "type": "Gene", "id": "KLHL7", "attributes": { "go_molecular_function": [ "protein binding", "protein homodimerization activity", "identical protein binding" ], "pathway_id": [], "essential_gene": null, "status": "CU", "uniprot_acc": "Q8IXQ5", "ensembl_id": "ENSG00000122550", "entrez_id": "55975", "chromosome_number": "7", "lastmodified": "2021-10-18T11:00:44.250009" }, "relationships": { "variant_set": { "meta": { "count": 1 }, "data": [ { "type": "SmallVariant", "id": "1749" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/KLHL7/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/genes/KLHL7/variants/?format=api" } }, "genecombination_set": { "meta": { "count": 1 }, "data": [ { "type": "GeneCombination", "id": "577" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/KLHL7/relationships/genecombination_set?format=api", "related": "https://olida.ibsquare.be/api/genes/KLHL7/genecombinations/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genes/KLHL7/?format=api" } }, { "type": "Gene", "id": "TNRC6C", "attributes": { "go_molecular_function": [ "protein binding", "nucleic acid binding" ], "pathway_id": [ "R-HSA-1912408", "R-HSA-162582", "R-HSA-8953897", "R-HSA-2262752", "R-HSA-74160", "R-HSA-4086398", "R-HSA-5683057", "R-HSA-6807070", "R-HSA-9024446", "R-HSA-3858494", "R-HSA-212436", "R-HSA-3700989", "R-HSA-9006931", "R-HSA-9022692", "R-HSA-2559580", "R-HSA-5687128", "R-HSA-426496", "R-HSA-2559583", "R-HSA-2559585", "R-HSA-8878171", "R-HSA-8939211", "R-HSA-5628897", "R-HSA-9018519", "R-HSA-8948700", "R-HSA-1912422", "R-HSA-8934593", "R-HSA-9029569", "R-HSA-8853884", "R-HSA-157118", "R-HSA-73857", "R-HSA-8936459", "R-HSA-8986944", "R-HSA-1257604", "R-HSA-195721", "R-HSA-8943723", "R-HSA-9006925", "R-HSA-211000" ], "essential_gene": null, "status": "CU", "uniprot_acc": "Q9HCJ0", "ensembl_id": "ENSG00000078687", "entrez_id": "57690", "chromosome_number": "17", "lastmodified": "2021-10-18T11:00:44.950924" }, "relationships": { "variant_set": { "meta": { "count": 1 }, "data": [ { "type": "SmallVariant", "id": "1751" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/TNRC6C/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/genes/TNRC6C/variants/?format=api" } }, "genecombination_set": { "meta": { "count": 1 }, "data": [ { "type": "GeneCombination", "id": "577" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/TNRC6C/relationships/genecombination_set?format=api", "related": "https://olida.ibsquare.be/api/genes/TNRC6C/genecombinations/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genes/TNRC6C/?format=api" } } ], "meta": { "database_name": "OLIgogenic diseases DAtabase (OLIDA)", "resource_url": "olida.ibsquare.be", "api_release_year": "2021", "api_developer": [ [ "Arnau Dillen", "arnau.dillen@ulb.ac.be" ], [ "Charlotte Nachtegael", "charlotte.nachtegael@ulb.be" ] ], "api_version": "0.3", "api_maintainers": [ [ "Charlotte Nachtegael", "charlotte.nachtegael@ulb.be" ] ], "api_documentation": [ "olida.ibsquare.be/api/swagger", "olida.ibsquare.be/api/redoc" ], "copyright": "Copyright (c) 2025 · OLIDA All Rights Reserved.", "license": "CC Attribution-NonCommercial 4.0 International License", "ontologies": { "ORDO": "http://bioportal.bioontology.org/ontologies/ORDO", "GENO": "http://purl.obolibrary.org/obo/geno.owl", "MI": "http://purl.obolibrary.org/obo/mi.owl", "NCIT": "http://purl.obolibrary.org/obo/ncit.owl", "OGI": "http://purl.obolibrary.org/obo/ogi.owl", "OGG": "http://purl.obolibrary.org/obo/ogg.owl" }, "relevant_publications_doi": [ "10.1093/nar/gkv1068", "10.1093/database/baac023" ], "size": 3 } }