Gene List
This API endpoint handles listing (/genes) and retrieval (/genes/<ID>/) of genes that are contained in the database due to their association to
genetic variants that are involved in at least one oligogenic combination in OLIDA.
GET /api/genecombinations/571/genes/?format=api
{ "data": [ { "type": "Gene", "id": "MYO18B", "attributes": { "go_molecular_function": [ "ATP binding", "cytoskeletal motor activity", "actin binding", "nucleotide binding" ], "pathway_id": [], "essential_gene": "Essential", "status": "CU", "uniprot_acc": "Q8IUG5", "ensembl_id": "ENSG00000133454", "entrez_id": "84700", "chromosome_number": "22", "lastmodified": "2021-10-18T11:00:44.440172" }, "relationships": { "variant_set": { "meta": { "count": 5 }, "data": [ { "type": "SmallVariant", "id": "702" }, { "type": "SmallVariant", "id": "714" }, { "type": "SmallVariant", "id": "716" }, { "type": "SmallVariant", "id": "1734" }, { "type": "SmallVariant", "id": "1735" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/MYO18B/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/genes/MYO18B/variants/?format=api" } }, "genecombination_set": { "meta": { "count": 4 }, "data": [ { "type": "GeneCombination", "id": "225" }, { "type": "GeneCombination", "id": "229" }, { "type": "GeneCombination", "id": "230" }, { "type": "GeneCombination", "id": "571" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/MYO18B/relationships/genecombination_set?format=api", "related": "https://olida.ibsquare.be/api/genes/MYO18B/genecombinations/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genes/MYO18B/?format=api" } }, { "type": "Gene", "id": "RYR3", "attributes": { "go_molecular_function": [ "['calcium-induced calcium release activity', 'calcium ion binding', 'ryanodine-sensitive calcium-release channel activity', 'calcium-release channel activity', 'calmodulin binding']" ], "pathway_id": [ "kegg_path:hsa04020", "kegg_path:hsa04371", "kegg_path:hsa04713", "kegg_path:hsa04921", "kegg_path:hsa04970", "kegg_path:hsa05010", "kegg_path:hsa05012", "kegg_path:hsa05020", "kegg_path:hsa05022", "R-HSA-2672351", "R-HSA-382551", "R-HSA-397014", "R-HSA-5576891", "R-HSA-5578775", "R-HSA-983712" ], "essential_gene": "Non-essential", "status": "CU", "uniprot_acc": "A0A0X1KG73", "ensembl_id": "None", "entrez_id": "ENSG00000198838", "chromosome_number": "15", "lastmodified": "2021-10-18T11:00:44.558256" }, "relationships": { "variant_set": { "meta": { "count": 4 }, "data": [ { "type": "SmallVariant", "id": "1733" }, { "type": "SmallVariant", "id": "2257" }, { "type": "SmallVariant", "id": "2265" }, { "type": "SmallVariant", "id": "3071" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/RYR3/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/genes/RYR3/variants/?format=api" } }, "genecombination_set": { "meta": { "count": 4 }, "data": [ { "type": "GeneCombination", "id": "571" }, { "type": "GeneCombination", "id": "761" }, { "type": "GeneCombination", "id": "762" }, { "type": "GeneCombination", "id": "1030" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/RYR3/relationships/genecombination_set?format=api", "related": "https://olida.ibsquare.be/api/genes/RYR3/genecombinations/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genes/RYR3/?format=api" } } ], "meta": { "database_name": "OLIgogenic diseases DAtabase (OLIDA)", "resource_url": "olida.ibsquare.be", "api_release_year": "2021", "api_developer": [ [ "Arnau Dillen", "arnau.dillen@ulb.ac.be" ], [ "Charlotte Nachtegael", "charlotte.nachtegael@ulb.be" ] ], "api_version": "0.3", "api_maintainers": [ [ "Charlotte Nachtegael", "charlotte.nachtegael@ulb.be" ] ], "api_documentation": [ "olida.ibsquare.be/api/swagger", "olida.ibsquare.be/api/redoc" ], "copyright": "Copyright (c) 2025 · OLIDA All Rights Reserved.", "license": "CC Attribution-NonCommercial 4.0 International License", "ontologies": { "ORDO": "http://bioportal.bioontology.org/ontologies/ORDO", "GENO": "http://purl.obolibrary.org/obo/geno.owl", "MI": "http://purl.obolibrary.org/obo/mi.owl", "NCIT": "http://purl.obolibrary.org/obo/ncit.owl", "OGI": "http://purl.obolibrary.org/obo/ogi.owl", "OGG": "http://purl.obolibrary.org/obo/ogg.owl" }, "relevant_publications_doi": [ "10.1093/nar/gkv1068", "10.1093/database/baac023" ], "size": 2 } }