Gene List
This API endpoint handles listing (/genes) and retrieval (/genes/<ID>/) of genes that are contained in the database due to their association to
genetic variants that are involved in at least one oligogenic combination in OLIDA.
GET /api/genecombinations/536/genes/?format=api
{ "data": [ { "type": "Gene", "id": "CELSR2", "attributes": { "go_molecular_function": [ "G protein-coupled receptor activity", "transmembrane signaling receptor activity", "calcium ion binding" ], "pathway_id": [], "essential_gene": "Non-essential", "status": "CU", "uniprot_acc": "Q9HCU4", "ensembl_id": "ENSG00000143126", "entrez_id": "1952", "chromosome_number": "1", "lastmodified": "2021-10-18T11:00:44.972153" }, "relationships": { "variant_set": { "meta": { "count": 7 }, "data": [ { "type": "SmallVariant", "id": "1519" }, { "type": "SmallVariant", "id": "1536" }, { "type": "SmallVariant", "id": "1617" }, { "type": "SmallVariant", "id": "1623" }, { "type": "SmallVariant", "id": "1650" }, { "type": "SmallVariant", "id": "1665" }, { "type": "SmallVariant", "id": "1691" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/CELSR2/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/genes/CELSR2/variants/?format=api" } }, "genecombination_set": { "meta": { "count": 11 }, "data": [ { "type": "GeneCombination", "id": "488" }, { "type": "GeneCombination", "id": "490" }, { "type": "GeneCombination", "id": "493" }, { "type": "GeneCombination", "id": "509" }, { "type": "GeneCombination", "id": "520" }, { "type": "GeneCombination", "id": "523" }, { "type": "GeneCombination", "id": "525" }, { "type": "GeneCombination", "id": "535" }, { "type": "GeneCombination", "id": "536" }, { "type": "GeneCombination", "id": "542" }, { "type": "GeneCombination", "id": "551" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/CELSR2/relationships/genecombination_set?format=api", "related": "https://olida.ibsquare.be/api/genes/CELSR2/genecombinations/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genes/CELSR2/?format=api" } }, { "type": "Gene", "id": "NOG", "attributes": { "go_molecular_function": [ "protein binding" ], "pathway_id": [ "R-HSA-201451", "R-HSA-9006936", "kegg_path:hsa04350", "R-HSA-162582" ], "essential_gene": "Essential", "status": "CU", "uniprot_acc": "Q13253", "ensembl_id": "ENSG00000183691", "entrez_id": "9241", "chromosome_number": "17", "lastmodified": "2021-10-18T11:00:44.248132" }, "relationships": { "variant_set": { "meta": { "count": 3 }, "data": [ { "type": "SmallVariant", "id": "1565" }, { "type": "SmallVariant", "id": "1651" }, { "type": "SmallVariant", "id": "1672" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/NOG/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/genes/NOG/variants/?format=api" } }, "genecombination_set": { "meta": { "count": 3 }, "data": [ { "type": "GeneCombination", "id": "503" }, { "type": "GeneCombination", "id": "536" }, { "type": "GeneCombination", "id": "545" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/NOG/relationships/genecombination_set?format=api", "related": "https://olida.ibsquare.be/api/genes/NOG/genecombinations/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genes/NOG/?format=api" } }, { "type": "Gene", "id": "SOD2", "attributes": { "go_molecular_function": [ "oxygen binding", "manganese ion binding", "enzyme binding" ], "pathway_id": [ "kegg_path:hsa04211", "R-HSA-9614085", "R-HSA-1643685", "R-HSA-9020591", "kegg_path:hsa04068", "R-HSA-1592230", "R-HSA-9645723", "R-HSA-168256", "R-HSA-8862803", "kegg_path:hsa04213", "R-HSA-73857", "R-HSA-1280215", "R-HSA-212436", "R-HSA-8863678", "R-HSA-447115", "R-HSA-9615017", "R-HSA-74160", "R-HSA-1852241", "R-HSA-2262752", "R-HSA-449147", "R-HSA-8953897", "kegg_path:hsa04146", "R-HSA-2151201", "R-HSA-8950505", "kegg_path:hsa05016", "R-HSA-3299685" ], "essential_gene": "Essential", "status": "CU", "uniprot_acc": "P04179", "ensembl_id": "ENSG00000112096", "entrez_id": "6648", "chromosome_number": "6", "lastmodified": "2021-10-18T11:00:44.756300" }, "relationships": { "variant_set": { "meta": { "count": 1 }, "data": [ { "type": "SmallVariant", "id": "1652" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/SOD2/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/genes/SOD2/variants/?format=api" } }, "genecombination_set": { "meta": { "count": 1 }, "data": [ { "type": "GeneCombination", "id": "536" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/SOD2/relationships/genecombination_set?format=api", "related": "https://olida.ibsquare.be/api/genes/SOD2/genecombinations/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genes/SOD2/?format=api" } } ], "meta": { "database_name": "OLIgogenic diseases DAtabase (OLIDA)", "resource_url": "olida.ibsquare.be", "api_release_year": "2021", "api_developer": [ [ "Arnau Dillen", "arnau.dillen@ulb.ac.be" ], [ "Charlotte Nachtegael", "charlotte.nachtegael@ulb.be" ] ], "api_version": "0.3", "api_maintainers": [ [ "Charlotte Nachtegael", "charlotte.nachtegael@ulb.be" ] ], "api_documentation": [ "olida.ibsquare.be/api/swagger", "olida.ibsquare.be/api/redoc" ], "copyright": "Copyright (c) 2025 · OLIDA All Rights Reserved.", "license": "CC Attribution-NonCommercial 4.0 International License", "ontologies": { "ORDO": "http://bioportal.bioontology.org/ontologies/ORDO", "GENO": "http://purl.obolibrary.org/obo/geno.owl", "MI": "http://purl.obolibrary.org/obo/mi.owl", "NCIT": "http://purl.obolibrary.org/obo/ncit.owl", "OGI": "http://purl.obolibrary.org/obo/ogi.owl", "OGG": "http://purl.obolibrary.org/obo/ogg.owl" }, "relevant_publications_doi": [ "10.1093/nar/gkv1068", "10.1093/database/baac023" ], "size": 3 } }