Gene List
This API endpoint handles listing (/genes) and retrieval (/genes/<ID>/) of genes that are contained in the database due to their association to
genetic variants that are involved in at least one oligogenic combination in OLIDA.
GET /api/genecombinations/534/genes/?format=api
{ "data": [ { "type": "Gene", "id": "CAT", "attributes": { "go_molecular_function": [ "catalase activity", "identical protein binding" ], "pathway_id": [ "kegg_path:hsa00630", "R-HSA-168249", "R-HSA-9614085", "kegg_path:hsa04211", "kegg_path:hsa04068", "R-HSA-168256", "kegg_path:hsa01200", "R-HSA-9033241", "R-HSA-73857", "kegg_path:hsa04213", "R-HSA-9609507", "kegg_path:hsa00380", "R-HSA-212436", "R-HSA-6798695", "kegg_path:hsa01100", "R-HSA-9615017", "kegg_path:hsa05022", "R-HSA-74160", "R-HSA-2262752", "kegg_path:hsa04146", "kegg_path:hsa05014", "R-HSA-8953897", "R-HSA-3299685" ], "essential_gene": "Non-essential", "status": "CU", "uniprot_acc": "P04040", "ensembl_id": "ENSG00000121691", "entrez_id": "847", "chromosome_number": "11", "lastmodified": "2021-10-18T11:00:44.969770" }, "relationships": { "variant_set": { "meta": { "count": 2 }, "data": [ { "type": "SmallVariant", "id": "1526" }, { "type": "SmallVariant", "id": "1646" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/CAT/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/genes/CAT/variants/?format=api" } }, "genecombination_set": { "meta": { "count": 2 }, "data": [ { "type": "GeneCombination", "id": "490" }, { "type": "GeneCombination", "id": "534" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/CAT/relationships/genecombination_set?format=api", "related": "https://olida.ibsquare.be/api/genes/CAT/genecombinations/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genes/CAT/?format=api" } }, { "type": "Gene", "id": "DVL1", "attributes": { "go_molecular_function": [ "protein binding", "enzyme binding", "frizzled binding" ], "pathway_id": [ "kegg_path:hsa04934", "R-HSA-9673324", "R-HSA-194315", "kegg_path:hsa04550", "kegg_path:hsa05165", "R-HSA-5368598", "R-HSA-5663205", "R-HSA-3858494", "R-HSA-4641258", "kegg_path:hsa04916", "kegg_path:hsa05022", "R-HSA-195258", "R-HSA-9658195", "kegg_path:hsa05200", "kegg_path:hsa04330", "R-HSA-162582", "kegg_path:hsa04310", "R-HSA-195721", "kegg_path:hsa04390", "R-HSA-4086400", "R-HSA-5663220", "kegg_path:hsa05010", "kegg_path:hsa04150", "R-HSA-201688", "kegg_path:hsa05224", "kegg_path:hsa05217", "R-HSA-1643685", "R-HSA-9664420", "kegg_path:hsa05225", "kegg_path:hsa05226", "R-HSA-201681", "R-HSA-4641262" ], "essential_gene": "Non-essential", "status": "CU", "uniprot_acc": "O14640", "ensembl_id": "ENSG00000107404", "entrez_id": "1855", "chromosome_number": "1", "lastmodified": "2021-10-18T11:00:44.455015" }, "relationships": { "variant_set": { "meta": { "count": 3 }, "data": [ { "type": "SmallVariant", "id": "1619" }, { "type": "SmallVariant", "id": "1645" }, { "type": "SmallVariant", "id": "1660" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/DVL1/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/genes/DVL1/variants/?format=api" } }, "genecombination_set": { "meta": { "count": 3 }, "data": [ { "type": "GeneCombination", "id": "521" }, { "type": "GeneCombination", "id": "534" }, { "type": "GeneCombination", "id": "540" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/DVL1/relationships/genecombination_set?format=api", "related": "https://olida.ibsquare.be/api/genes/DVL1/genecombinations/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genes/DVL1/?format=api" } }, { "type": "Gene", "id": "SFRP1", "attributes": { "go_molecular_function": [ "Wnt-protein binding", "protein binding" ], "pathway_id": [ "kegg_path:hsa04310", "R-HSA-195721", "R-HSA-201681", "R-HSA-162582", "R-HSA-3772470" ], "essential_gene": "Non-essential", "status": "CU", "uniprot_acc": "Q8N474", "ensembl_id": "ENSG00000104332", "entrez_id": "6422", "chromosome_number": "8", "lastmodified": "2021-10-18T11:00:44.364442" }, "relationships": { "variant_set": { "meta": { "count": 1 }, "data": [ { "type": "SmallVariant", "id": "1647" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/SFRP1/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/genes/SFRP1/variants/?format=api" } }, "genecombination_set": { "meta": { "count": 1 }, "data": [ { "type": "GeneCombination", "id": "534" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/SFRP1/relationships/genecombination_set?format=api", "related": "https://olida.ibsquare.be/api/genes/SFRP1/genecombinations/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genes/SFRP1/?format=api" } } ], "meta": { "database_name": "OLIgogenic diseases DAtabase (OLIDA)", "resource_url": "olida.ibsquare.be", "api_release_year": "2021", "api_developer": [ [ "Arnau Dillen", "arnau.dillen@ulb.ac.be" ], [ "Charlotte Nachtegael", "charlotte.nachtegael@ulb.be" ] ], "api_version": "0.3", "api_maintainers": [ [ "Charlotte Nachtegael", "charlotte.nachtegael@ulb.be" ] ], "api_documentation": [ "olida.ibsquare.be/api/swagger", "olida.ibsquare.be/api/redoc" ], "copyright": "Copyright (c) 2025 · OLIDA All Rights Reserved.", "license": "CC Attribution-NonCommercial 4.0 International License", "ontologies": { "ORDO": "http://bioportal.bioontology.org/ontologies/ORDO", "GENO": "http://purl.obolibrary.org/obo/geno.owl", "MI": "http://purl.obolibrary.org/obo/mi.owl", "NCIT": "http://purl.obolibrary.org/obo/ncit.owl", "OGI": "http://purl.obolibrary.org/obo/ogi.owl", "OGG": "http://purl.obolibrary.org/obo/ogg.owl" }, "relevant_publications_doi": [ "10.1093/nar/gkv1068", "10.1093/database/baac023" ], "size": 3 } }