This API endpoint handles listing (/genes) and retrieval (/genes/<ID>/) of genes that are contained in the database due to their association to
genetic variants that are involved in at least one oligogenic combination in OLIDA.

GET /api/genecombinations/531/genes/?format=api
HTTP 200 OK
Allow: GET, HEAD, OPTIONS
Content-Type: application/vnd.api+json
Vary: Accept

{
    "data": [
        {
            "type": "Gene",
            "id": "GART",
            "attributes": {
                "go_molecular_function": [
                    "phosphoribosylglycinamide formyltransferase activity",
                    "transferase activity",
                    "nucleotide binding",
                    "ligase activity",
                    "catalytic activity",
                    "phosphoribosylformylglycinamidine cyclo-ligase activity",
                    "phosphoribosylamine-glycine ligase activity",
                    "metal ion binding"
                ],
                "pathway_id": [
                    "R-HSA-73817",
                    "kegg_path:hsa01100",
                    "kegg_path:hsa01523",
                    "R-HSA-15869",
                    "R-HSA-8956320",
                    "R-HSA-1430728",
                    "kegg_path:hsa00670",
                    "kegg_path:hsa00230"
                ],
                "essential_gene": null,
                "status": "CU",
                "uniprot_acc": "P22102",
                "ensembl_id": "ENSG00000159131",
                "entrez_id": "2618",
                "chromosome_number": "21",
                "lastmodified": "2021-10-18T11:00:44.738512"
            },
            "relationships": {
                "variant_set": {
                    "meta": {
                        "count": 2
                    },
                    "data": [
                        {
                            "type": "SmallVariant",
                            "id": "1600"
                        },
                        {
                            "type": "SmallVariant",
                            "id": "1640"
                        }
                    ],
                    "links": {
                        "self": "https://olida.ibsquare.be/api/genes/GART/relationships/variant_set?format=api",
                        "related": "https://olida.ibsquare.be/api/genes/GART/variants/?format=api"
                    }
                },
                "genecombination_set": {
                    "meta": {
                        "count": 2
                    },
                    "data": [
                        {
                            "type": "GeneCombination",
                            "id": "514"
                        },
                        {
                            "type": "GeneCombination",
                            "id": "531"
                        }
                    ],
                    "links": {
                        "self": "https://olida.ibsquare.be/api/genes/GART/relationships/genecombination_set?format=api",
                        "related": "https://olida.ibsquare.be/api/genes/GART/genecombinations/?format=api"
                    }
                }
            },
            "links": {
                "self": "https://olida.ibsquare.be/api/genes/GART/?format=api"
            }
        },
        {
            "type": "Gene",
            "id": "NOS2",
            "attributes": {
                "go_molecular_function": [
                    "protein binding",
                    "FMN binding",
                    "nitric-oxide synthase activity",
                    "heme binding",
                    "tetrahydrobiopterin binding",
                    "arginine binding",
                    "flavin adenine dinucleotide binding",
                    "NADP binding",
                    "metal ion binding",
                    "calmodulin binding",
                    "oxidoreductase activity"
                ],
                "pathway_id": [
                    "R-HSA-9635486",
                    "kegg_path:hsa05010",
                    "kegg_path:hsa05145",
                    "R-HSA-9636249",
                    "R-HSA-9637687",
                    "kegg_path:hsa01100",
                    "kegg_path:hsa05146",
                    "R-HSA-1222556",
                    "R-HSA-109582",
                    "R-HSA-1643685",
                    "R-HSA-9637690",
                    "kegg_path:hsa00330",
                    "kegg_path:hsa05152",
                    "R-HSA-168249",
                    "R-HSA-9033241",
                    "R-HSA-168256",
                    "R-HSA-9609507",
                    "kegg_path:hsa05222",
                    "kegg_path:hsa00220",
                    "kegg_path:hsa04066",
                    "R-HSA-418346",
                    "kegg_path:hsa04371",
                    "R-HSA-392154",
                    "kegg_path:hsa05142",
                    "R-HSA-5663205",
                    "kegg_path:hsa05133",
                    "kegg_path:hsa05140",
                    "kegg_path:hsa05200",
                    "R-HSA-449147",
                    "kegg_path:hsa05022",
                    "kegg_path:hsa04020",
                    "R-HSA-6785807",
                    "kegg_path:hsa04146",
                    "kegg_path:hsa04926",
                    "kegg_path:hsa05014",
                    "R-HSA-1280215"
                ],
                "essential_gene": "Non-essential",
                "status": "CU",
                "uniprot_acc": "P35228",
                "ensembl_id": "ENSG00000007171",
                "entrez_id": "4843",
                "chromosome_number": "17",
                "lastmodified": "2021-10-18T11:00:44.533688"
            },
            "relationships": {
                "variant_set": {
                    "meta": {
                        "count": 2
                    },
                    "data": [
                        {
                            "type": "SmallVariant",
                            "id": "1591"
                        },
                        {
                            "type": "SmallVariant",
                            "id": "1639"
                        }
                    ],
                    "links": {
                        "self": "https://olida.ibsquare.be/api/genes/NOS2/relationships/variant_set?format=api",
                        "related": "https://olida.ibsquare.be/api/genes/NOS2/variants/?format=api"
                    }
                },
                "genecombination_set": {
                    "meta": {
                        "count": 2
                    },
                    "data": [
                        {
                            "type": "GeneCombination",
                            "id": "512"
                        },
                        {
                            "type": "GeneCombination",
                            "id": "531"
                        }
                    ],
                    "links": {
                        "self": "https://olida.ibsquare.be/api/genes/NOS2/relationships/genecombination_set?format=api",
                        "related": "https://olida.ibsquare.be/api/genes/NOS2/genecombinations/?format=api"
                    }
                }
            },
            "links": {
                "self": "https://olida.ibsquare.be/api/genes/NOS2/?format=api"
            }
        }
    ],
    "meta": {
        "database_name": "OLIgogenic diseases DAtabase (OLIDA)",
        "resource_url": "olida.ibsquare.be",
        "api_release_year": "2021",
        "api_developer": [
            [
                "Arnau Dillen",
                "arnau.dillen@ulb.ac.be"
            ],
            [
                "Charlotte Nachtegael",
                "charlotte.nachtegael@ulb.be"
            ]
        ],
        "api_version": "0.3",
        "api_maintainers": [
            [
                "Charlotte Nachtegael",
                "charlotte.nachtegael@ulb.be"
            ]
        ],
        "api_documentation": [
            "olida.ibsquare.be/api/swagger",
            "olida.ibsquare.be/api/redoc"
        ],
        "copyright": "Copyright (c) 2024 · OLIDA All Rights Reserved.",
        "license": "CC Attribution-NonCommercial 4.0 International License",
        "ontologies": {
            "ORDO": "http://bioportal.bioontology.org/ontologies/ORDO",
            "GENO": "http://purl.obolibrary.org/obo/geno.owl",
            "MI": "http://purl.obolibrary.org/obo/mi.owl",
            "NCIT": "http://purl.obolibrary.org/obo/ncit.owl",
            "OGI": "http://purl.obolibrary.org/obo/ogi.owl",
            "OGG": "http://purl.obolibrary.org/obo/ogg.owl"
        },
        "relevant_publications_doi": [
            "10.1093/nar/gkv1068",
            "10.1093/database/baac023"
        ],
        "size": 2
    }
}