Gene List
This API endpoint handles listing (/genes) and retrieval (/genes/<ID>/) of genes that are contained in the database due to their association to
genetic variants that are involved in at least one oligogenic combination in OLIDA.
GET /api/genecombinations/531/genes/?format=api
{ "data": [ { "type": "Gene", "id": "GART", "attributes": { "go_molecular_function": [ "phosphoribosylglycinamide formyltransferase activity", "transferase activity", "nucleotide binding", "ligase activity", "catalytic activity", "phosphoribosylformylglycinamidine cyclo-ligase activity", "phosphoribosylamine-glycine ligase activity", "metal ion binding" ], "pathway_id": [ "R-HSA-73817", "kegg_path:hsa01100", "kegg_path:hsa01523", "R-HSA-15869", "R-HSA-8956320", "R-HSA-1430728", "kegg_path:hsa00670", "kegg_path:hsa00230" ], "essential_gene": null, "status": "CU", "uniprot_acc": "P22102", "ensembl_id": "ENSG00000159131", "entrez_id": "2618", "chromosome_number": "21", "lastmodified": "2021-10-18T11:00:44.738512" }, "relationships": { "variant_set": { "meta": { "count": 2 }, "data": [ { "type": "SmallVariant", "id": "1600" }, { "type": "SmallVariant", "id": "1640" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/GART/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/genes/GART/variants/?format=api" } }, "genecombination_set": { "meta": { "count": 2 }, "data": [ { "type": "GeneCombination", "id": "514" }, { "type": "GeneCombination", "id": "531" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/GART/relationships/genecombination_set?format=api", "related": "https://olida.ibsquare.be/api/genes/GART/genecombinations/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genes/GART/?format=api" } }, { "type": "Gene", "id": "NOS2", "attributes": { "go_molecular_function": [ "protein binding", "FMN binding", "nitric-oxide synthase activity", "heme binding", "tetrahydrobiopterin binding", "arginine binding", "flavin adenine dinucleotide binding", "NADP binding", "metal ion binding", "calmodulin binding", "oxidoreductase activity" ], "pathway_id": [ "R-HSA-9635486", "kegg_path:hsa05010", "kegg_path:hsa05145", "R-HSA-9636249", "R-HSA-9637687", "kegg_path:hsa01100", "kegg_path:hsa05146", "R-HSA-1222556", "R-HSA-109582", "R-HSA-1643685", "R-HSA-9637690", "kegg_path:hsa00330", "kegg_path:hsa05152", "R-HSA-168249", "R-HSA-9033241", "R-HSA-168256", "R-HSA-9609507", "kegg_path:hsa05222", "kegg_path:hsa00220", "kegg_path:hsa04066", "R-HSA-418346", "kegg_path:hsa04371", "R-HSA-392154", "kegg_path:hsa05142", "R-HSA-5663205", "kegg_path:hsa05133", "kegg_path:hsa05140", "kegg_path:hsa05200", "R-HSA-449147", "kegg_path:hsa05022", "kegg_path:hsa04020", "R-HSA-6785807", "kegg_path:hsa04146", "kegg_path:hsa04926", "kegg_path:hsa05014", "R-HSA-1280215" ], "essential_gene": "Non-essential", "status": "CU", "uniprot_acc": "P35228", "ensembl_id": "ENSG00000007171", "entrez_id": "4843", "chromosome_number": "17", "lastmodified": "2021-10-18T11:00:44.533688" }, "relationships": { "variant_set": { "meta": { "count": 2 }, "data": [ { "type": "SmallVariant", "id": "1591" }, { "type": "SmallVariant", "id": "1639" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/NOS2/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/genes/NOS2/variants/?format=api" } }, "genecombination_set": { "meta": { "count": 2 }, "data": [ { "type": "GeneCombination", "id": "512" }, { "type": "GeneCombination", "id": "531" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/NOS2/relationships/genecombination_set?format=api", "related": "https://olida.ibsquare.be/api/genes/NOS2/genecombinations/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genes/NOS2/?format=api" } } ], "meta": { "database_name": "OLIgogenic diseases DAtabase (OLIDA)", "resource_url": "olida.ibsquare.be", "api_release_year": "2021", "api_developer": [ [ "Arnau Dillen", "arnau.dillen@ulb.ac.be" ], [ "Charlotte Nachtegael", "charlotte.nachtegael@ulb.be" ] ], "api_version": "0.3", "api_maintainers": [ [ "Charlotte Nachtegael", "charlotte.nachtegael@ulb.be" ] ], "api_documentation": [ "olida.ibsquare.be/api/swagger", "olida.ibsquare.be/api/redoc" ], "copyright": "Copyright (c) 2025 · OLIDA All Rights Reserved.", "license": "CC Attribution-NonCommercial 4.0 International License", "ontologies": { "ORDO": "http://bioportal.bioontology.org/ontologies/ORDO", "GENO": "http://purl.obolibrary.org/obo/geno.owl", "MI": "http://purl.obolibrary.org/obo/mi.owl", "NCIT": "http://purl.obolibrary.org/obo/ncit.owl", "OGI": "http://purl.obolibrary.org/obo/ogi.owl", "OGG": "http://purl.obolibrary.org/obo/ogg.owl" }, "relevant_publications_doi": [ "10.1093/nar/gkv1068", "10.1093/database/baac023" ], "size": 2 } }