Gene List
This API endpoint handles listing (/genes) and retrieval (/genes/<ID>/) of genes that are contained in the database due to their association to
genetic variants that are involved in at least one oligogenic combination in OLIDA.
GET /api/genecombinations/526/genes/?format=api
{ "data": [ { "type": "Gene", "id": "CELSR3", "attributes": { "go_molecular_function": [ "['G protein-coupled receptor activity', 'calcium ion binding', 'protein binding']" ], "pathway_id": [], "essential_gene": "Essential", "status": "CU", "uniprot_acc": "Q9NYQ7", "ensembl_id": "None", "entrez_id": "ENSG00000008300", "chromosome_number": "3", "lastmodified": "2021-10-18T11:00:44.329047" }, "relationships": { "variant_set": { "meta": { "count": 5 }, "data": [ { "type": "SmallVariant", "id": "1528" }, { "type": "SmallVariant", "id": "1566" }, { "type": "SmallVariant", "id": "1611" }, { "type": "SmallVariant", "id": "1612" }, { "type": "SmallVariant", "id": "3115" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/CELSR3/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/genes/CELSR3/variants/?format=api" } }, "genecombination_set": { "meta": { "count": 5 }, "data": [ { "type": "GeneCombination", "id": "490" }, { "type": "GeneCombination", "id": "503" }, { "type": "GeneCombination", "id": "518" }, { "type": "GeneCombination", "id": "526" }, { "type": "GeneCombination", "id": "1043" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/CELSR3/relationships/genecombination_set?format=api", "related": "https://olida.ibsquare.be/api/genes/CELSR3/genecombinations/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genes/CELSR3/?format=api" } }, { "type": "Gene", "id": "JARID2", "attributes": { "go_molecular_function": [ "chromatin binding", "histone H3-tri/di/monomethyl-lysine-4 demethylase activity", "DNA binding", "histone demethylase activity" ], "pathway_id": [ "R-HSA-74160", "R-HSA-212165", "R-HSA-212300", "kegg_path:hsa04550" ], "essential_gene": "Essential", "status": "CU", "uniprot_acc": "Q92833", "ensembl_id": "ENSG00000008083", "entrez_id": "3720", "chromosome_number": "6", "lastmodified": "2021-10-18T11:00:44.389224" }, "relationships": { "variant_set": { "meta": { "count": 1 }, "data": [ { "type": "SmallVariant", "id": "1627" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/JARID2/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/genes/JARID2/variants/?format=api" } }, "genecombination_set": { "meta": { "count": 2 }, "data": [ { "type": "GeneCombination", "id": "524" }, { "type": "GeneCombination", "id": "526" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/JARID2/relationships/genecombination_set?format=api", "related": "https://olida.ibsquare.be/api/genes/JARID2/genecombinations/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genes/JARID2/?format=api" } }, { "type": "Gene", "id": "TRDMT1", "attributes": { "go_molecular_function": [ "transferase activity", "tRNA methyltransferase activity", "tRNA (cytosine-5-)-methyltransferase activity", "RNA binding", "methyltransferase activity" ], "pathway_id": [ "R-HSA-6782315", "R-HSA-8953854", "R-HSA-72306" ], "essential_gene": "Non-essential", "status": "CU", "uniprot_acc": "O14717", "ensembl_id": "ENSG00000107614", "entrez_id": "1787", "chromosome_number": "10", "lastmodified": "2021-10-18T11:00:44.817614" }, "relationships": { "variant_set": { "meta": { "count": 1 }, "data": [ { "type": "SmallVariant", "id": "1628" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/TRDMT1/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/genes/TRDMT1/variants/?format=api" } }, "genecombination_set": { "meta": { "count": 1 }, "data": [ { "type": "GeneCombination", "id": "526" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/TRDMT1/relationships/genecombination_set?format=api", "related": "https://olida.ibsquare.be/api/genes/TRDMT1/genecombinations/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genes/TRDMT1/?format=api" } } ], "meta": { "database_name": "OLIgogenic diseases DAtabase (OLIDA)", "resource_url": "olida.ibsquare.be", "api_release_year": "2021", "api_developer": [ [ "Arnau Dillen", "arnau.dillen@ulb.ac.be" ], [ "Charlotte Nachtegael", "charlotte.nachtegael@ulb.be" ] ], "api_version": "0.3", "api_maintainers": [ [ "Charlotte Nachtegael", "charlotte.nachtegael@ulb.be" ] ], "api_documentation": [ "olida.ibsquare.be/api/swagger", "olida.ibsquare.be/api/redoc" ], "copyright": "Copyright (c) 2025 · OLIDA All Rights Reserved.", "license": "CC Attribution-NonCommercial 4.0 International License", "ontologies": { "ORDO": "http://bioportal.bioontology.org/ontologies/ORDO", "GENO": "http://purl.obolibrary.org/obo/geno.owl", "MI": "http://purl.obolibrary.org/obo/mi.owl", "NCIT": "http://purl.obolibrary.org/obo/ncit.owl", "OGI": "http://purl.obolibrary.org/obo/ogi.owl", "OGG": "http://purl.obolibrary.org/obo/ogg.owl" }, "relevant_publications_doi": [ "10.1093/nar/gkv1068", "10.1093/database/baac023" ], "size": 3 } }