Gene List
This API endpoint handles listing (/genes) and retrieval (/genes/<ID>/) of genes that are contained in the database due to their association to
genetic variants that are involved in at least one oligogenic combination in OLIDA.
GET /api/genecombinations/513/genes/?format=api
{ "data": [ { "type": "Gene", "id": "DACT1", "attributes": { "go_molecular_function": [ "histone deacetylase binding", "beta-catenin binding", "protein binding", "RNA polymerase II-specific DNA-binding transcription factor binding" ], "pathway_id": [ "R-HSA-195721", "R-HSA-201681", "R-HSA-162582", "R-HSA-4641258" ], "essential_gene": "Essential", "status": "CU", "uniprot_acc": "Q9NYF0", "ensembl_id": "ENSG00000165617", "entrez_id": "51339", "chromosome_number": "14", "lastmodified": "2021-10-18T11:00:44.335571" }, "relationships": { "variant_set": { "meta": { "count": 2 }, "data": [ { "type": "SmallVariant", "id": "1595" }, { "type": "SmallVariant", "id": "1685" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/DACT1/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/genes/DACT1/variants/?format=api" } }, "genecombination_set": { "meta": { "count": 2 }, "data": [ { "type": "GeneCombination", "id": "513" }, { "type": "GeneCombination", "id": "549" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/DACT1/relationships/genecombination_set?format=api", "related": "https://olida.ibsquare.be/api/genes/DACT1/genecombinations/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genes/DACT1/?format=api" } }, { "type": "Gene", "id": "FTCD", "attributes": { "go_molecular_function": [ "protein binding", "transferase activity", "microtubule binding", "folic acid binding", "catalytic activity", "lyase activity", "formimidoyltetrahydrofolate cyclodeaminase activity", "glutamate formimidoyltransferase activity" ], "pathway_id": [ "R-HSA-1430728", "R-HSA-71291", "kegg_path:hsa01100", "R-HSA-70921", "kegg_path:hsa00340", "kegg_path:hsa00670" ], "essential_gene": null, "status": "CU", "uniprot_acc": "O95954", "ensembl_id": "ENSG00000160282", "entrez_id": "10841", "chromosome_number": "21", "lastmodified": "2021-10-18T11:00:44.283350" }, "relationships": { "variant_set": { "meta": { "count": 1 }, "data": [ { "type": "SmallVariant", "id": "1533" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/FTCD/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/genes/FTCD/variants/?format=api" } }, "genecombination_set": { "meta": { "count": 2 }, "data": [ { "type": "GeneCombination", "id": "492" }, { "type": "GeneCombination", "id": "513" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/FTCD/relationships/genecombination_set?format=api", "related": "https://olida.ibsquare.be/api/genes/FTCD/genecombinations/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genes/FTCD/?format=api" } }, { "type": "Gene", "id": "NAT1", "attributes": { "go_molecular_function": [ "arylamine N-acetyltransferase activity", "acyltransferase activity", "acetyltransferase activity", "transferase activity" ], "pathway_id": [ "R-HSA-211859", "kegg_path:hsa00232", "kegg_path:hsa01100", "R-HSA-156582", "kegg_path:hsa05204", "kegg_path:hsa00983", "R-HSA-1430728", "R-HSA-156580" ], "essential_gene": "Non-essential", "status": "CU", "uniprot_acc": "F5H5R8", "ensembl_id": "ENSG00000171428", "entrez_id": "9", "chromosome_number": "8", "lastmodified": "2021-10-18T11:00:44.358214" }, "relationships": { "variant_set": { "meta": { "count": 2 }, "data": [ { "type": "SmallVariant", "id": "1597" }, { "type": "SmallVariant", "id": "1657" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/NAT1/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/genes/NAT1/variants/?format=api" } }, "genecombination_set": { "meta": { "count": 3 }, "data": [ { "type": "GeneCombination", "id": "513" }, { "type": "GeneCombination", "id": "538" }, { "type": "GeneCombination", "id": "551" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/NAT1/relationships/genecombination_set?format=api", "related": "https://olida.ibsquare.be/api/genes/NAT1/genecombinations/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genes/NAT1/?format=api" } }, { "type": "Gene", "id": "SNX13", "attributes": { "go_molecular_function": [ "phosphatidylinositol binding", "lipid binding", "phosphatidylinositol-3-phosphate binding" ], "pathway_id": [], "essential_gene": "Essential", "status": "CU", "uniprot_acc": "Q9Y5W8", "ensembl_id": "ENSG00000071189", "entrez_id": "23161", "chromosome_number": "7", "lastmodified": "2021-10-18T11:00:44.761516" }, "relationships": { "variant_set": { "meta": { "count": 3 }, "data": [ { "type": "SmallVariant", "id": "1596" }, { "type": "SmallVariant", "id": "1680" }, { "type": "SmallVariant", "id": "1692" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/SNX13/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/genes/SNX13/variants/?format=api" } }, "genecombination_set": { "meta": { "count": 3 }, "data": [ { "type": "GeneCombination", "id": "513" }, { "type": "GeneCombination", "id": "547" }, { "type": "GeneCombination", "id": "551" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/SNX13/relationships/genecombination_set?format=api", "related": "https://olida.ibsquare.be/api/genes/SNX13/genecombinations/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genes/SNX13/?format=api" } } ], "meta": { "database_name": "OLIgogenic diseases DAtabase (OLIDA)", "resource_url": "olida.ibsquare.be", "api_release_year": "2021", "api_developer": [ [ "Arnau Dillen", "arnau.dillen@ulb.ac.be" ], [ "Charlotte Nachtegael", "charlotte.nachtegael@ulb.be" ] ], "api_version": "0.3", "api_maintainers": [ [ "Charlotte Nachtegael", "charlotte.nachtegael@ulb.be" ] ], "api_documentation": [ "olida.ibsquare.be/api/swagger", "olida.ibsquare.be/api/redoc" ], "copyright": "Copyright (c) 2025 · OLIDA All Rights Reserved.", "license": "CC Attribution-NonCommercial 4.0 International License", "ontologies": { "ORDO": "http://bioportal.bioontology.org/ontologies/ORDO", "GENO": "http://purl.obolibrary.org/obo/geno.owl", "MI": "http://purl.obolibrary.org/obo/mi.owl", "NCIT": "http://purl.obolibrary.org/obo/ncit.owl", "OGI": "http://purl.obolibrary.org/obo/ogi.owl", "OGG": "http://purl.obolibrary.org/obo/ogg.owl" }, "relevant_publications_doi": [ "10.1093/nar/gkv1068", "10.1093/database/baac023" ], "size": 4 } }