Gene List
This API endpoint handles listing (/genes) and retrieval (/genes/<ID>/) of genes that are contained in the database due to their association to
genetic variants that are involved in at least one oligogenic combination in OLIDA.
GET /api/genecombinations/481/genes/?format=api
{ "data": [ { "type": "Gene", "id": "DCHS1", "attributes": { "go_molecular_function": [ "cadherin binding", "calcium ion binding" ], "pathway_id": [ "kegg_path:hsa04392" ], "essential_gene": "Essential", "status": "CU", "uniprot_acc": "Q96JQ0", "ensembl_id": "ENSG00000166341", "entrez_id": "8642", "chromosome_number": "11", "lastmodified": "2021-10-18T11:00:44.372944" }, "relationships": { "variant_set": { "meta": { "count": 5 }, "data": [ { "type": "SmallVariant", "id": "1501" }, { "type": "SmallVariant", "id": "1513" }, { "type": "SmallVariant", "id": "1527" }, { "type": "SmallVariant", "id": "1545" }, { "type": "SmallVariant", "id": "1634" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/DCHS1/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/genes/DCHS1/variants/?format=api" } }, "genecombination_set": { "meta": { "count": 5 }, "data": [ { "type": "GeneCombination", "id": "481" }, { "type": "GeneCombination", "id": "486" }, { "type": "GeneCombination", "id": "490" }, { "type": "GeneCombination", "id": "496" }, { "type": "GeneCombination", "id": "529" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/DCHS1/relationships/genecombination_set?format=api", "related": "https://olida.ibsquare.be/api/genes/DCHS1/genecombinations/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genes/DCHS1/?format=api" } }, { "type": "Gene", "id": "PTCH1", "attributes": { "go_molecular_function": [ "['cyclin binding', 'patched binding', 'smoothened binding', 'protein-containing complex binding', 'hedgehog family protein binding', 'protein binding', 'heparin binding', 'cholesterol binding', 'hedgehog receptor activity']" ], "pathway_id": [ "kegg_path:hsa04024", "kegg_path:hsa04340", "kegg_path:hsa04360", "kegg_path:hsa05200", "kegg_path:hsa05205", "kegg_path:hsa05217", "R-HSA-162582", "R-HSA-372790", "R-HSA-373080", "R-HSA-500792", "R-HSA-5358351", "R-HSA-5610787", "R-HSA-5632681", "R-HSA-5632684", "R-HSA-5635838" ], "essential_gene": "Essential", "status": "CU", "uniprot_acc": "Q13635", "ensembl_id": "None", "entrez_id": "ENSG00000185920", "chromosome_number": "9", "lastmodified": "2021-10-18T11:00:44.300396" }, "relationships": { "variant_set": { "meta": { "count": 6 }, "data": [ { "type": "SmallVariant", "id": "1471" }, { "type": "SmallVariant", "id": "1502" }, { "type": "SmallVariant", "id": "1512" }, { "type": "SmallVariant", "id": "3316" }, { "type": "SmallVariant", "id": "3317" }, { "type": "SmallVariant", "id": "3318" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/PTCH1/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/genes/PTCH1/variants/?format=api" } }, "genecombination_set": { "meta": { "count": 4 }, "data": [ { "type": "GeneCombination", "id": "470" }, { "type": "GeneCombination", "id": "481" }, { "type": "GeneCombination", "id": "485" }, { "type": "GeneCombination", "id": "1116" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/PTCH1/relationships/genecombination_set?format=api", "related": "https://olida.ibsquare.be/api/genes/PTCH1/genecombinations/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genes/PTCH1/?format=api" } } ], "meta": { "database_name": "OLIgogenic diseases DAtabase (OLIDA)", "resource_url": "olida.ibsquare.be", "api_release_year": "2021", "api_developer": [ [ "Arnau Dillen", "arnau.dillen@ulb.ac.be" ], [ "Charlotte Nachtegael", "charlotte.nachtegael@ulb.be" ] ], "api_version": "0.3", "api_maintainers": [ [ "Charlotte Nachtegael", "charlotte.nachtegael@ulb.be" ] ], "api_documentation": [ "olida.ibsquare.be/api/swagger", "olida.ibsquare.be/api/redoc" ], "copyright": "Copyright (c) 2025 · OLIDA All Rights Reserved.", "license": "CC Attribution-NonCommercial 4.0 International License", "ontologies": { "ORDO": "http://bioportal.bioontology.org/ontologies/ORDO", "GENO": "http://purl.obolibrary.org/obo/geno.owl", "MI": "http://purl.obolibrary.org/obo/mi.owl", "NCIT": "http://purl.obolibrary.org/obo/ncit.owl", "OGI": "http://purl.obolibrary.org/obo/ogi.owl", "OGG": "http://purl.obolibrary.org/obo/ogg.owl" }, "relevant_publications_doi": [ "10.1093/nar/gkv1068", "10.1093/database/baac023" ], "size": 2 } }