Gene List
This API endpoint handles listing (/genes) and retrieval (/genes/<ID>/) of genes that are contained in the database due to their association to
genetic variants that are involved in at least one oligogenic combination in OLIDA.
GET /api/genecombinations/477/genes/?format=api
{ "data": [ { "type": "Gene", "id": "ITGB3", "attributes": { "go_molecular_function": [ "fibronectin binding", "integrin binding" ], "pathway_id": [ "R-HSA-6802948", "kegg_path:hsa05163", "R-HSA-1266738", "R-HSA-3000178", "R-HSA-5673001", "kegg_path:hsa05414", "R-HSA-3000170", "R-HSA-3000171", "kegg_path:hsa04512", "R-HSA-5663202", "R-HSA-162582", "R-HSA-372708", "R-HSA-5683057", "R-HSA-4420097", "kegg_path:hsa04810", "R-HSA-9006934", "kegg_path:hsa05410", "R-HSA-1474244", "R-HSA-354192", "kegg_path:hsa04015", "R-HSA-373760", "kegg_path:hsa04380", "kegg_path:hsa04510", "R-HSA-109582", "kegg_path:hsa04640", "kegg_path:hsa04611", "R-HSA-5674135", "kegg_path:hsa04919", "R-HSA-216083", "kegg_path:hsa05165", "R-HSA-6802955", "R-HSA-76005", "kegg_path:hsa05168", "R-HSA-210990", "R-HSA-422475", "R-HSA-194138", "R-HSA-9675108", "kegg_path:hsa05418", "R-HSA-202733", "R-HSA-5684996", "R-HSA-6802952", "kegg_path:hsa04613", "R-HSA-2129379", "R-HSA-9649948", "kegg_path:hsa05205", "R-HSA-445144", "R-HSA-9656223", "R-HSA-6802946", "kegg_path:hsa04145", "kegg_path:hsa05412", "kegg_path:hsa04151", "R-HSA-1643685", "R-HSA-114608", "R-HSA-1566948", "kegg_path:hsa05206", "R-HSA-354194", "kegg_path:hsa05410", "R-HSA-9006934", "kegg_path:hsa04810", "R-HSA-76002", "R-HSA-6802949", "R-HSA-109582", "R-HSA-76009", "kegg_path:hsa04380", "kegg_path:hsa04510", "R-HSA-6802957", "kegg_path:hsa04015", "R-HSA-373760", "R-HSA-354192", "R-HSA-1474244", "R-HSA-6802946", "R-HSA-445144", "R-HSA-9656223", "kegg_path:hsa05205", "R-HSA-2129379", "R-HSA-9649948", "kegg_path:hsa04613", "kegg_path:hsa05168", "R-HSA-210990", "R-HSA-76005", "R-HSA-6802955", "kegg_path:hsa05165", "kegg_path:hsa05418", "R-HSA-202733", "R-HSA-5684996", "R-HSA-6802952", "R-HSA-194138", "R-HSA-9675108", "R-HSA-422475", "R-HSA-76002", "R-HSA-354194", "kegg_path:hsa05206", "R-HSA-6802957", "R-HSA-76009", "R-HSA-6802949", "kegg_path:hsa04151", "R-HSA-1643685", "kegg_path:hsa05412", "kegg_path:hsa04145", "R-HSA-1566948", "R-HSA-114608", "R-HSA-5663202", "kegg_path:hsa04512", "R-HSA-4420097", "R-HSA-5683057", "R-HSA-162582", "R-HSA-372708", "R-HSA-5673001", "kegg_path:hsa05163", "R-HSA-1266738", "R-HSA-3000178", "R-HSA-6802948", "R-HSA-3000170", "R-HSA-3000171", "kegg_path:hsa05414", "kegg_path:hsa04611", "kegg_path:hsa04640", "R-HSA-216083", "kegg_path:hsa04919", "R-HSA-5674135" ], "essential_gene": "Essential", "status": "CU", "uniprot_acc": "H3BM21", "ensembl_id": "ENSG00000259207", "entrez_id": "3690", "chromosome_number": "17", "lastmodified": "2021-10-18T11:00:44.481551" }, "relationships": { "variant_set": { "meta": { "count": 2 }, "data": [ { "type": "SmallVariant", "id": "1491" }, { "type": "SmallVariant", "id": "1492" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/ITGB3/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/genes/ITGB3/variants/?format=api" } }, "genecombination_set": { "meta": { "count": 1 }, "data": [ { "type": "GeneCombination", "id": "477" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/ITGB3/relationships/genecombination_set?format=api", "related": "https://olida.ibsquare.be/api/genes/ITGB3/genecombinations/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genes/ITGB3/?format=api" } }, { "type": "Gene", "id": "TUBB1", "attributes": { "go_molecular_function": [ "GTP binding", "nucleotide binding", "structural constituent of cytoskeleton", "GTPase activity" ], "pathway_id": [ "R-HSA-389957", "R-HSA-190828", "R-HSA-437239", "R-HSA-5610787", "R-HSA-389958", "R-HSA-5620924", "R-HSA-1632852", "R-HSA-69275", "kegg_path:hsa05132", "R-HSA-199991", "R-HSA-1643685", "R-HSA-199977", "R-HSA-68882", "R-HSA-1280218", "R-HSA-5358351", "R-HSA-9646399", "R-HSA-190872", "R-HSA-6807878", "R-HSA-9668328", "R-HSA-2995410", "R-HSA-1445148", "R-HSA-373760", "R-HSA-5653656", "R-HSA-109582", "R-HSA-112315", "R-HSA-453274", "R-HSA-9619483", "R-HSA-380320", "R-HSA-5617833", "R-HSA-9609690", "R-HSA-597592", "R-HSA-195258", "R-HSA-2467813", "R-HSA-9609646", "kegg_path:hsa05016", "R-HSA-8955332", "kegg_path:hsa05014", "kegg_path:hsa05130", "R-HSA-9663891", "R-HSA-194315", "R-HSA-6811434", "R-HSA-422475", "R-HSA-9675108", "R-HSA-112316", "R-HSA-1640170", "R-HSA-5626467", "R-HSA-68886", "R-HSA-8856688", "R-HSA-392499", "R-HSA-9609736", "R-HSA-68877", "R-HSA-190840", "R-HSA-69278", "R-HSA-112314", "R-HSA-390466", "R-HSA-6811436", "R-HSA-168256", "R-HSA-8852276", "kegg_path:hsa05010", "kegg_path:hsa05020", "R-HSA-948021", "kegg_path:hsa04145", "kegg_path:hsa05012", "R-HSA-2555396", "R-HSA-6811442", "R-HSA-9648025", "R-HSA-3371497", "R-HSA-391251", "R-HSA-157858", "R-HSA-2500257", "R-HSA-2262752", "R-HSA-983231", "kegg_path:hsa05022", "R-HSA-1852241", "R-HSA-162582", "R-HSA-8953897", "kegg_path:hsa04540", "R-HSA-983189", "R-HSA-1266738", "R-HSA-9612973", "R-HSA-446203", "R-HSA-2132295", "R-HSA-5663205", "R-HSA-190861", "R-HSA-389960", "R-HSA-389977", "R-HSA-438064", "R-HSA-442755", "R-HSA-5663220" ], "essential_gene": "Non-essential", "status": "CU", "uniprot_acc": "Q9H4B7", "ensembl_id": "ENSG00000101162", "entrez_id": "81027", "chromosome_number": "20", "lastmodified": "2021-10-18T11:00:44.745744" }, "relationships": { "variant_set": { "meta": { "count": 1 }, "data": [ { "type": "SmallVariant", "id": "1493" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/TUBB1/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/genes/TUBB1/variants/?format=api" } }, "genecombination_set": { "meta": { "count": 1 }, "data": [ { "type": "GeneCombination", "id": "477" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/TUBB1/relationships/genecombination_set?format=api", "related": "https://olida.ibsquare.be/api/genes/TUBB1/genecombinations/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genes/TUBB1/?format=api" } } ], "meta": { "database_name": "OLIgogenic diseases DAtabase (OLIDA)", "resource_url": "olida.ibsquare.be", "api_release_year": "2021", "api_developer": [ [ "Arnau Dillen", "arnau.dillen@ulb.ac.be" ], [ "Charlotte Nachtegael", "charlotte.nachtegael@ulb.be" ] ], "api_version": "0.3", "api_maintainers": [ [ "Charlotte Nachtegael", "charlotte.nachtegael@ulb.be" ] ], "api_documentation": [ "olida.ibsquare.be/api/swagger", "olida.ibsquare.be/api/redoc" ], "copyright": "Copyright (c) 2025 · OLIDA All Rights Reserved.", "license": "CC Attribution-NonCommercial 4.0 International License", "ontologies": { "ORDO": "http://bioportal.bioontology.org/ontologies/ORDO", "GENO": "http://purl.obolibrary.org/obo/geno.owl", "MI": "http://purl.obolibrary.org/obo/mi.owl", "NCIT": "http://purl.obolibrary.org/obo/ncit.owl", "OGI": "http://purl.obolibrary.org/obo/ogi.owl", "OGG": "http://purl.obolibrary.org/obo/ogg.owl" }, "relevant_publications_doi": [ "10.1093/nar/gkv1068", "10.1093/database/baac023" ], "size": 2 } }