Gene List
This API endpoint handles listing (/genes) and retrieval (/genes/<ID>/) of genes that are contained in the database due to their association to
genetic variants that are involved in at least one oligogenic combination in OLIDA.
GET /api/genecombinations/471/genes/?format=api
{ "data": [ { "type": "Gene", "id": "BOC", "attributes": { "go_molecular_function": [ "protein binding" ], "pathway_id": [ "R-HSA-5632681", "R-HSA-5358351", "R-HSA-162582", "R-HSA-5632684", "kegg_path:hsa04360", "kegg_path:hsa04340", "R-HSA-5635838" ], "essential_gene": "Non-essential", "status": "CU", "uniprot_acc": "Q9BWV1", "ensembl_id": "ENSG00000144857", "entrez_id": "91653", "chromosome_number": "3", "lastmodified": "2021-10-18T11:00:44.798184" }, "relationships": { "variant_set": { "meta": { "count": 2 }, "data": [ { "type": "SmallVariant", "id": "1472" }, { "type": "SmallVariant", "id": "1476" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/BOC/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/genes/BOC/variants/?format=api" } }, "genecombination_set": { "meta": { "count": 2 }, "data": [ { "type": "GeneCombination", "id": "471" }, { "type": "GeneCombination", "id": "472" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/BOC/relationships/genecombination_set?format=api", "related": "https://olida.ibsquare.be/api/genes/BOC/genecombinations/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genes/BOC/?format=api" } }, { "type": "Gene", "id": "HIC1", "attributes": { "go_molecular_function": [ "metal ion binding", "protein binding", "sequence-specific double-stranded DNA binding", "DNA-binding transcription factor activity", "DNA binding" ], "pathway_id": [ "R-HSA-2990846", "R-HSA-3108232", "R-HSA-3232118", "R-HSA-392499", "R-HSA-597592" ], "essential_gene": "Essential", "status": "CU", "uniprot_acc": "Q14526", "ensembl_id": "ENSG00000177374", "entrez_id": "3090", "chromosome_number": "17", "lastmodified": "2021-10-18T11:00:44.311009" }, "relationships": { "variant_set": { "meta": { "count": 1 }, "data": [ { "type": "SmallVariant", "id": "1474" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/HIC1/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/genes/HIC1/variants/?format=api" } }, "genecombination_set": { "meta": { "count": 1 }, "data": [ { "type": "GeneCombination", "id": "471" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/HIC1/relationships/genecombination_set?format=api", "related": "https://olida.ibsquare.be/api/genes/HIC1/genecombinations/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genes/HIC1/?format=api" } }, { "type": "Gene", "id": "SCUBE2", "attributes": { "go_molecular_function": [ "['lipid binding', 'calcium ion binding', 'protein binding']" ], "pathway_id": [ "R-HSA-162582", "R-HSA-5358346", "R-HSA-5358351", "R-HSA-5362798" ], "essential_gene": null, "status": "CU", "uniprot_acc": "Q9NQ36", "ensembl_id": "None", "entrez_id": "ENSG00000175356", "chromosome_number": "11", "lastmodified": "2021-10-18T11:00:44.941425" }, "relationships": { "variant_set": { "meta": { "count": 5 }, "data": [ { "type": "SmallVariant", "id": "1473" }, { "type": "SmallVariant", "id": "1477" }, { "type": "SmallVariant", "id": "1839" }, { "type": "SmallVariant", "id": "2742" }, { "type": "SmallVariant", "id": "2743" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/SCUBE2/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/genes/SCUBE2/variants/?format=api" } }, "genecombination_set": { "meta": { "count": 4 }, "data": [ { "type": "GeneCombination", "id": "471" }, { "type": "GeneCombination", "id": "472" }, { "type": "GeneCombination", "id": "609" }, { "type": "GeneCombination", "id": "913" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/SCUBE2/relationships/genecombination_set?format=api", "related": "https://olida.ibsquare.be/api/genes/SCUBE2/genecombinations/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genes/SCUBE2/?format=api" } } ], "meta": { "database_name": "OLIgogenic diseases DAtabase (OLIDA)", "resource_url": "olida.ibsquare.be", "api_release_year": "2021", "api_developer": [ [ "Arnau Dillen", "arnau.dillen@ulb.ac.be" ], [ "Charlotte Nachtegael", "charlotte.nachtegael@ulb.be" ] ], "api_version": "0.3", "api_maintainers": [ [ "Charlotte Nachtegael", "charlotte.nachtegael@ulb.be" ] ], "api_documentation": [ "olida.ibsquare.be/api/swagger", "olida.ibsquare.be/api/redoc" ], "copyright": "Copyright (c) 2025 · OLIDA All Rights Reserved.", "license": "CC Attribution-NonCommercial 4.0 International License", "ontologies": { "ORDO": "http://bioportal.bioontology.org/ontologies/ORDO", "GENO": "http://purl.obolibrary.org/obo/geno.owl", "MI": "http://purl.obolibrary.org/obo/mi.owl", "NCIT": "http://purl.obolibrary.org/obo/ncit.owl", "OGI": "http://purl.obolibrary.org/obo/ogi.owl", "OGG": "http://purl.obolibrary.org/obo/ogg.owl" }, "relevant_publications_doi": [ "10.1093/nar/gkv1068", "10.1093/database/baac023" ], "size": 3 } }