Gene List
This API endpoint handles listing (/genes) and retrieval (/genes/<ID>/) of genes that are contained in the database due to their association to
genetic variants that are involved in at least one oligogenic combination in OLIDA.
GET /api/genecombinations/462/genes/?format=api
{ "data": [ { "type": "Gene", "id": "GATA4", "attributes": { "go_molecular_function": [ "protein kinase binding", "protein binding", "NFAT protein binding", "RNA polymerase II-specific DNA-binding transcription factor binding", "transcription cis-regulatory region binding", "DNA-binding transcription factor binding", "sequence-specific DNA binding", "DNA-binding transcription factor activity, RNA polymerase II-specific", "cis-regulatory region sequence-specific DNA binding", "DNA binding" ], "pathway_id": [ "kegg_path:hsa04530", "R-HSA-2980736", "R-HSA-392499", "kegg_path:hsa04919", "kegg_path:hsa04919", "kegg_path:hsa04530", "R-HSA-400508", "R-HSA-9690406", "R-HSA-73857", "kegg_path:hsa04022", "kegg_path:hsa04218", "R-HSA-1266738", "R-HSA-5576891", "kegg_path:hsa04022", "kegg_path:hsa04218", "R-HSA-212436", "R-HSA-109582", "R-HSA-397014", "R-HSA-2032785", "R-HSA-5578768", "R-HSA-74160", "R-HSA-983231", "R-HSA-400511" ], "essential_gene": "Essential", "status": "CU", "uniprot_acc": "P43694", "ensembl_id": "ENSG00000136574", "entrez_id": "2626", "chromosome_number": "8", "lastmodified": "2021-10-18T11:00:44.826434" }, "relationships": { "variant_set": { "meta": { "count": 2 }, "data": [ { "type": "SmallVariant", "id": "1447" }, { "type": "SmallVariant", "id": "1449" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/GATA4/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/genes/GATA4/variants/?format=api" } }, "genecombination_set": { "meta": { "count": 2 }, "data": [ { "type": "GeneCombination", "id": "461" }, { "type": "GeneCombination", "id": "462" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/GATA4/relationships/genecombination_set?format=api", "related": "https://olida.ibsquare.be/api/genes/GATA4/genecombinations/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genes/GATA4/?format=api" } }, { "type": "Gene", "id": "LHCGR", "attributes": { "go_molecular_function": [ "['luteinizing hormone receptor activity', 'choriogonadotropin hormone binding', 'choriogonadotropin hormone receptor activity', 'G protein-coupled peptide receptor activity']" ], "pathway_id": [ "kegg_path:hsa04020", "kegg_path:hsa04024", "kegg_path:hsa04080", "kegg_path:hsa04913", "kegg_path:hsa04917", "R-HSA-162582", "R-HSA-1643685", "R-HSA-372790", "R-HSA-373076", "R-HSA-375281", "R-HSA-388396", "R-HSA-418555", "R-HSA-500792", "R-HSA-5663205", "R-HSA-9658195", "R-HSA-9660821", "R-HSA-9662851", "R-HSA-9664433" ], "essential_gene": "Non-essential", "status": "CU", "uniprot_acc": "P22888", "ensembl_id": "None", "entrez_id": "ENSG00000138039", "chromosome_number": "2", "lastmodified": "2021-10-18T11:00:44.960635" }, "relationships": { "variant_set": { "meta": { "count": 3 }, "data": [ { "type": "SmallVariant", "id": "1450" }, { "type": "SmallVariant", "id": "2326" }, { "type": "SmallVariant", "id": "3261" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/LHCGR/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/genes/LHCGR/variants/?format=api" } }, "genecombination_set": { "meta": { "count": 3 }, "data": [ { "type": "GeneCombination", "id": "462" }, { "type": "GeneCombination", "id": "782" }, { "type": "GeneCombination", "id": "1096" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/LHCGR/relationships/genecombination_set?format=api", "related": "https://olida.ibsquare.be/api/genes/LHCGR/genecombinations/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genes/LHCGR/?format=api" } } ], "meta": { "database_name": "OLIgogenic diseases DAtabase (OLIDA)", "resource_url": "olida.ibsquare.be", "api_release_year": "2021", "api_developer": [ [ "Arnau Dillen", "arnau.dillen@ulb.ac.be" ], [ "Charlotte Nachtegael", "charlotte.nachtegael@ulb.be" ] ], "api_version": "0.3", "api_maintainers": [ [ "Charlotte Nachtegael", "charlotte.nachtegael@ulb.be" ] ], "api_documentation": [ "olida.ibsquare.be/api/swagger", "olida.ibsquare.be/api/redoc" ], "copyright": "Copyright (c) 2025 · OLIDA All Rights Reserved.", "license": "CC Attribution-NonCommercial 4.0 International License", "ontologies": { "ORDO": "http://bioportal.bioontology.org/ontologies/ORDO", "GENO": "http://purl.obolibrary.org/obo/geno.owl", "MI": "http://purl.obolibrary.org/obo/mi.owl", "NCIT": "http://purl.obolibrary.org/obo/ncit.owl", "OGI": "http://purl.obolibrary.org/obo/ogi.owl", "OGG": "http://purl.obolibrary.org/obo/ogg.owl" }, "relevant_publications_doi": [ "10.1093/nar/gkv1068", "10.1093/database/baac023" ], "size": 2 } }