Gene List
This API endpoint handles listing (/genes) and retrieval (/genes/<ID>/) of genes that are contained in the database due to their association to
genetic variants that are involved in at least one oligogenic combination in OLIDA.
GET /api/genecombinations/450/genes/?format=api
{ "data": [ { "type": "Gene", "id": "C9orf72", "attributes": { "go_molecular_function": [ "guanyl-nucleotide exchange factor activity", "small GTPase binding", "protein binding" ], "pathway_id": [ "kegg_path:hsa04140", "kegg_path:hsa05014", "kegg_path:hsa05022" ], "essential_gene": null, "status": "CU", "uniprot_acc": "Q96LT7", "ensembl_id": "None", "entrez_id": "ENSG00000147894", "chromosome_number": "9", "lastmodified": "2021-10-18T11:00:44.423366" }, "relationships": { "variant_set": { "meta": { "count": 5 }, "data": [ { "type": "CopyNumberVariant", "id": "530" }, { "type": "CopyNumberVariant", "id": "1225" }, { "type": "CopyNumberVariant", "id": "1694" }, { "type": "CopyNumberVariant", "id": "1808" }, { "type": "CopyNumberVariant", "id": "3061" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/C9orf72/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/genes/C9orf72/variants/?format=api" } }, "genecombination_set": { "meta": { "count": 25 }, "data": [ { "type": "GeneCombination", "id": "175" }, { "type": "GeneCombination", "id": "176" }, { "type": "GeneCombination", "id": "177" }, { "type": "GeneCombination", "id": "377" }, { "type": "GeneCombination", "id": "390" }, { "type": "GeneCombination", "id": "413" }, { "type": "GeneCombination", "id": "428" }, { "type": "GeneCombination", "id": "429" }, { "type": "GeneCombination", "id": "430" }, { "type": "GeneCombination", "id": "431" }, { "type": "GeneCombination", "id": "432" }, { "type": "GeneCombination", "id": "433" }, { "type": "GeneCombination", "id": "435" }, { "type": "GeneCombination", "id": "449" }, { "type": "GeneCombination", "id": "450" }, { "type": "GeneCombination", "id": "552" }, { "type": "GeneCombination", "id": "556" }, { "type": "GeneCombination", "id": "557" }, { "type": "GeneCombination", "id": "558" }, { "type": "GeneCombination", "id": "600" }, { "type": "GeneCombination", "id": "603" }, { "type": "GeneCombination", "id": "553" }, { "type": "GeneCombination", "id": "1147" }, { "type": "GeneCombination", "id": "1148" }, { "type": "GeneCombination", "id": "1149" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/C9orf72/relationships/genecombination_set?format=api", "related": "https://olida.ibsquare.be/api/genes/C9orf72/genecombinations/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genes/C9orf72/?format=api" } }, { "type": "Gene", "id": "PSEN2", "attributes": { "go_molecular_function": [ "protein binding", "peptidase activity" ], "pathway_id": [ "R-HSA-9013700", "R-HSA-2894862", "R-HSA-9012852", "R-HSA-2644603", "R-HSA-2894858", "kegg_path:hsa05010", "R-HSA-9006934", "R-HSA-157118", "R-HSA-2122948", "R-HSA-204998", "R-HSA-3928665", "R-HSA-193704", "R-HSA-2644606", "R-HSA-9017802", "R-HSA-2979096", "R-HSA-2644602", "R-HSA-1643685", "R-HSA-193692", "kegg_path:hsa04722", "R-HSA-9013694", "R-HSA-1980145", "R-HSA-9013507", "R-HSA-9675108", "R-HSA-422475", "R-HSA-1266738", "kegg_path:hsa04330", "R-HSA-2682334", "R-HSA-1236394", "R-HSA-162582", "R-HSA-1980143", "kegg_path:hsa05022", "R-HSA-1251985", "R-HSA-205043", "R-HSA-5663202", "R-HSA-73887" ], "essential_gene": "Non-essential", "status": "CU", "uniprot_acc": "P49810", "ensembl_id": "ENSG00000143801", "entrez_id": "5664", "chromosome_number": "1", "lastmodified": "2021-10-18T11:00:44.695582" }, "relationships": { "variant_set": { "meta": { "count": 1 }, "data": [ { "type": "SmallVariant", "id": "1427" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/PSEN2/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/genes/PSEN2/variants/?format=api" } }, "genecombination_set": { "meta": { "count": 1 }, "data": [ { "type": "GeneCombination", "id": "450" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/PSEN2/relationships/genecombination_set?format=api", "related": "https://olida.ibsquare.be/api/genes/PSEN2/genecombinations/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genes/PSEN2/?format=api" } } ], "meta": { "database_name": "OLIgogenic diseases DAtabase (OLIDA)", "resource_url": "olida.ibsquare.be", "api_release_year": "2021", "api_developer": [ [ "Arnau Dillen", "arnau.dillen@ulb.ac.be" ], [ "Charlotte Nachtegael", "charlotte.nachtegael@ulb.be" ] ], "api_version": "0.3", "api_maintainers": [ [ "Charlotte Nachtegael", "charlotte.nachtegael@ulb.be" ] ], "api_documentation": [ "olida.ibsquare.be/api/swagger", "olida.ibsquare.be/api/redoc" ], "copyright": "Copyright (c) 2025 · OLIDA All Rights Reserved.", "license": "CC Attribution-NonCommercial 4.0 International License", "ontologies": { "ORDO": "http://bioportal.bioontology.org/ontologies/ORDO", "GENO": "http://purl.obolibrary.org/obo/geno.owl", "MI": "http://purl.obolibrary.org/obo/mi.owl", "NCIT": "http://purl.obolibrary.org/obo/ncit.owl", "OGI": "http://purl.obolibrary.org/obo/ogi.owl", "OGG": "http://purl.obolibrary.org/obo/ogg.owl" }, "relevant_publications_doi": [ "10.1093/nar/gkv1068", "10.1093/database/baac023" ], "size": 2 } }