Gene List
This API endpoint handles listing (/genes) and retrieval (/genes/<ID>/) of genes that are contained in the database due to their association to
genetic variants that are involved in at least one oligogenic combination in OLIDA.
GET /api/genecombinations/436/genes/?format=api
{ "data": [ { "type": "Gene", "id": "BMP4", "attributes": { "go_molecular_function": [ "['growth factor activity', 'BMP receptor binding', 'protein binding', 'chemoattractant activity', 'heparin binding', 'co-receptor binding', 'cytokine activity']" ], "pathway_id": [ "kegg_path:hsa04060", "kegg_path:hsa04350", "kegg_path:hsa04390", "kegg_path:hsa04550", "kegg_path:hsa04919", "kegg_path:hsa05200", "kegg_path:hsa05217", "kegg_path:hsa05418", "R-HSA-1474244", "R-HSA-1566948", "R-HSA-2129379", "R-HSA-381426", "R-HSA-392499", "R-HSA-597592", "R-HSA-8957275", "kegg_path:hsa04060", "kegg_path:hsa04350", "kegg_path:hsa04390", "kegg_path:hsa04550", "kegg_path:hsa04919", "kegg_path:hsa05200", "kegg_path:hsa05217", "kegg_path:hsa05418" ], "essential_gene": "Essential", "status": "CU", "uniprot_acc": "P12644", "ensembl_id": "None", "entrez_id": "ENSG00000125378", "chromosome_number": "14", "lastmodified": "2021-10-18T11:00:44.362577" }, "relationships": { "variant_set": { "meta": { "count": 4 }, "data": [ { "type": "SmallVariant", "id": "864" }, { "type": "SmallVariant", "id": "1383" }, { "type": "SmallVariant", "id": "2165" }, { "type": "SmallVariant", "id": "2775" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/BMP4/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/genes/BMP4/variants/?format=api" } }, "genecombination_set": { "meta": { "count": 4 }, "data": [ { "type": "GeneCombination", "id": "269" }, { "type": "GeneCombination", "id": "436" }, { "type": "GeneCombination", "id": "737" }, { "type": "GeneCombination", "id": "928" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/BMP4/relationships/genecombination_set?format=api", "related": "https://olida.ibsquare.be/api/genes/BMP4/genecombinations/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genes/BMP4/?format=api" } }, { "type": "Gene", "id": "DACH1", "attributes": { "go_molecular_function": [ "DNA-binding transcription factor activity, RNA polymerase II-specific", "DNA-binding transcription factor activity", "protein binding", "RNA polymerase II cis-regulatory region sequence-specific DNA binding" ], "pathway_id": [], "essential_gene": "Essential", "status": "CU", "uniprot_acc": "Q9UI36", "ensembl_id": "ENSG00000276644", "entrez_id": "1602", "chromosome_number": "13", "lastmodified": "2021-10-18T11:00:44.608542" }, "relationships": { "variant_set": { "meta": { "count": 1 }, "data": [ { "type": "SmallVariant", "id": "1384" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/DACH1/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/genes/DACH1/variants/?format=api" } }, "genecombination_set": { "meta": { "count": 1 }, "data": [ { "type": "GeneCombination", "id": "436" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/DACH1/relationships/genecombination_set?format=api", "related": "https://olida.ibsquare.be/api/genes/DACH1/genecombinations/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genes/DACH1/?format=api" } } ], "meta": { "database_name": "OLIgogenic diseases DAtabase (OLIDA)", "resource_url": "olida.ibsquare.be", "api_release_year": "2021", "api_developer": [ [ "Arnau Dillen", "arnau.dillen@ulb.ac.be" ], [ "Charlotte Nachtegael", "charlotte.nachtegael@ulb.be" ] ], "api_version": "0.3", "api_maintainers": [ [ "Charlotte Nachtegael", "charlotte.nachtegael@ulb.be" ] ], "api_documentation": [ "olida.ibsquare.be/api/swagger", "olida.ibsquare.be/api/redoc" ], "copyright": "Copyright (c) 2025 · OLIDA All Rights Reserved.", "license": "CC Attribution-NonCommercial 4.0 International License", "ontologies": { "ORDO": "http://bioportal.bioontology.org/ontologies/ORDO", "GENO": "http://purl.obolibrary.org/obo/geno.owl", "MI": "http://purl.obolibrary.org/obo/mi.owl", "NCIT": "http://purl.obolibrary.org/obo/ncit.owl", "OGI": "http://purl.obolibrary.org/obo/ogi.owl", "OGG": "http://purl.obolibrary.org/obo/ogg.owl" }, "relevant_publications_doi": [ "10.1093/nar/gkv1068", "10.1093/database/baac023" ], "size": 2 } }