Gene List
This API endpoint handles listing (/genes) and retrieval (/genes/<ID>/) of genes that are contained in the database due to their association to
genetic variants that are involved in at least one oligogenic combination in OLIDA.
GET /api/genecombinations/383/genes/?format=api
{ "data": [ { "type": "Gene", "id": "DYSF", "attributes": { "go_molecular_function": [ "protein binding", "calcium-dependent phospholipid binding", "lipid binding", "calcium ion binding", "phospholipid binding", "metal ion binding" ], "pathway_id": [ "R-HSA-397014", "R-HSA-445355" ], "essential_gene": "Non-essential", "status": "CU", "uniprot_acc": "O75923", "ensembl_id": "ENSG00000135636", "entrez_id": "8291", "chromosome_number": "2", "lastmodified": "2021-10-18T11:00:44.541002" }, "relationships": { "variant_set": { "meta": { "count": 2 }, "data": [ { "type": "SmallVariant", "id": "1194" }, { "type": "SmallVariant", "id": "1195" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/DYSF/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/genes/DYSF/variants/?format=api" } }, "genecombination_set": { "meta": { "count": 1 }, "data": [ { "type": "GeneCombination", "id": "383" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/DYSF/relationships/genecombination_set?format=api", "related": "https://olida.ibsquare.be/api/genes/DYSF/genecombinations/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genes/DYSF/?format=api" } }, { "type": "Gene", "id": "MYH7", "attributes": { "go_molecular_function": [ "['calmodulin binding', 'protein binding', 'microfilament motor activity', 'actin filament binding', 'ATP binding']" ], "pathway_id": [ "kegg_path:hsa04022", "kegg_path:hsa04260", "kegg_path:hsa04261", "kegg_path:hsa04919", "kegg_path:hsa05410", "kegg_path:hsa05414", "kegg_path:hsa05416" ], "essential_gene": null, "status": "CU", "uniprot_acc": "P12883", "ensembl_id": "None", "entrez_id": "ENSG00000092054", "chromosome_number": "14", "lastmodified": "2021-10-18T11:00:44.959780" }, "relationships": { "variant_set": { "meta": { "count": 13 }, "data": [ { "type": "SmallVariant", "id": "134" }, { "type": "SmallVariant", "id": "456" }, { "type": "SmallVariant", "id": "458" }, { "type": "SmallVariant", "id": "893" }, { "type": "SmallVariant", "id": "962" }, { "type": "SmallVariant", "id": "1190" }, { "type": "SmallVariant", "id": "1196" }, { "type": "SmallVariant", "id": "1331" }, { "type": "SmallVariant", "id": "2113" }, { "type": "SmallVariant", "id": "2115" }, { "type": "SmallVariant", "id": "2575" }, { "type": "SmallVariant", "id": "3754" }, { "type": "SmallVariant", "id": "3755" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/MYH7/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/genes/MYH7/variants/?format=api" } }, "genecombination_set": { "meta": { "count": 11 }, "data": [ { "type": "GeneCombination", "id": "48" }, { "type": "GeneCombination", "id": "151" }, { "type": "GeneCombination", "id": "152" }, { "type": "GeneCombination", "id": "277" }, { "type": "GeneCombination", "id": "308" }, { "type": "GeneCombination", "id": "381" }, { "type": "GeneCombination", "id": "383" }, { "type": "GeneCombination", "id": "414" }, { "type": "GeneCombination", "id": "729" }, { "type": "GeneCombination", "id": "728" }, { "type": "GeneCombination", "id": "1269" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/MYH7/relationships/genecombination_set?format=api", "related": "https://olida.ibsquare.be/api/genes/MYH7/genecombinations/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genes/MYH7/?format=api" } } ], "meta": { "database_name": "OLIgogenic diseases DAtabase (OLIDA)", "resource_url": "olida.ibsquare.be", "api_release_year": "2021", "api_developer": [ [ "Arnau Dillen", "arnau.dillen@ulb.ac.be" ], [ "Charlotte Nachtegael", "charlotte.nachtegael@ulb.be" ] ], "api_version": "0.3", "api_maintainers": [ [ "Charlotte Nachtegael", "charlotte.nachtegael@ulb.be" ] ], "api_documentation": [ "olida.ibsquare.be/api/swagger", "olida.ibsquare.be/api/redoc" ], "copyright": "Copyright (c) 2025 · OLIDA All Rights Reserved.", "license": "CC Attribution-NonCommercial 4.0 International License", "ontologies": { "ORDO": "http://bioportal.bioontology.org/ontologies/ORDO", "GENO": "http://purl.obolibrary.org/obo/geno.owl", "MI": "http://purl.obolibrary.org/obo/mi.owl", "NCIT": "http://purl.obolibrary.org/obo/ncit.owl", "OGI": "http://purl.obolibrary.org/obo/ogi.owl", "OGG": "http://purl.obolibrary.org/obo/ogg.owl" }, "relevant_publications_doi": [ "10.1093/nar/gkv1068", "10.1093/database/baac023" ], "size": 2 } }