Gene List
This API endpoint handles listing (/genes) and retrieval (/genes/<ID>/) of genes that are contained in the database due to their association to
genetic variants that are involved in at least one oligogenic combination in OLIDA.
GET /api/genecombinations/376/genes/?format=api
{ "data": [ { "type": "Gene", "id": "CACNA1G", "attributes": { "go_molecular_function": [ "low voltage-gated calcium channel activity", "voltage-gated ion channel activity", "voltage-gated calcium channel activity", "calcium channel activity" ], "pathway_id": [ "kegg_path:hsa04010", "kegg_path:hsa04927", "kegg_path:hsa04020", "R-HSA-419037", "kegg_path:hsa04925", "kegg_path:hsa04930", "kegg_path:hsa04713", "kegg_path:hsa04929", "R-HSA-422475", "R-HSA-375165", "R-HSA-9675108", "kegg_path:hsa04934", "R-HSA-1266738" ], "essential_gene": "Non-essential", "status": "CU", "uniprot_acc": "O43497", "ensembl_id": "ENSG00000006283", "entrez_id": "8913", "chromosome_number": "17", "lastmodified": "2021-10-18T11:00:44.607553" }, "relationships": { "variant_set": { "meta": { "count": 1 }, "data": [ { "type": "SmallVariant", "id": "1170" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/CACNA1G/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/genes/CACNA1G/variants/?format=api" } }, "genecombination_set": { "meta": { "count": 1 }, "data": [ { "type": "GeneCombination", "id": "376" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/CACNA1G/relationships/genecombination_set?format=api", "related": "https://olida.ibsquare.be/api/genes/CACNA1G/genecombinations/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genes/CACNA1G/?format=api" } }, { "type": "Gene", "id": "KCNQ3", "attributes": { "go_molecular_function": [ "protein binding", "potassium channel activity", "voltage-gated potassium channel activity", "delayed rectifier potassium channel activity", "ion channel activity", "calmodulin binding" ], "pathway_id": [ "R-HSA-112316", "R-HSA-445095", "R-HSA-1296071", "R-HSA-1296072", "kegg_path:hsa04725", "R-HSA-373760", "R-HSA-9675108", "R-HSA-422475", "R-HSA-1266738" ], "essential_gene": "Essential", "status": "CU", "uniprot_acc": "O43525", "ensembl_id": "ENSG00000184156", "entrez_id": "3786", "chromosome_number": "8", "lastmodified": "2021-10-18T11:00:44.612201" }, "relationships": { "variant_set": { "meta": { "count": 1 }, "data": [ { "type": "SmallVariant", "id": "1169" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/KCNQ3/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/genes/KCNQ3/variants/?format=api" } }, "genecombination_set": { "meta": { "count": 1 }, "data": [ { "type": "GeneCombination", "id": "376" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/KCNQ3/relationships/genecombination_set?format=api", "related": "https://olida.ibsquare.be/api/genes/KCNQ3/genecombinations/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genes/KCNQ3/?format=api" } } ], "meta": { "database_name": "OLIgogenic diseases DAtabase (OLIDA)", "resource_url": "olida.ibsquare.be", "api_release_year": "2021", "api_developer": [ [ "Arnau Dillen", "arnau.dillen@ulb.ac.be" ], [ "Charlotte Nachtegael", "charlotte.nachtegael@ulb.be" ] ], "api_version": "0.3", "api_maintainers": [ [ "Charlotte Nachtegael", "charlotte.nachtegael@ulb.be" ] ], "api_documentation": [ "olida.ibsquare.be/api/swagger", "olida.ibsquare.be/api/redoc" ], "copyright": "Copyright (c) 2025 · OLIDA All Rights Reserved.", "license": "CC Attribution-NonCommercial 4.0 International License", "ontologies": { "ORDO": "http://bioportal.bioontology.org/ontologies/ORDO", "GENO": "http://purl.obolibrary.org/obo/geno.owl", "MI": "http://purl.obolibrary.org/obo/mi.owl", "NCIT": "http://purl.obolibrary.org/obo/ncit.owl", "OGI": "http://purl.obolibrary.org/obo/ogi.owl", "OGG": "http://purl.obolibrary.org/obo/ogg.owl" }, "relevant_publications_doi": [ "10.1093/nar/gkv1068", "10.1093/database/baac023" ], "size": 2 } }