Gene Combination Instance – Django REST framework

This API endpoint handles listing (/references) and retrieval (/references/<ID>/) of References from the database
that support the inclusion of at least one oligogenic combination in OLIDA.

GET /api/genecombinations/370/?format=api

HTTP 200 OK
Allow: GET, HEAD, OPTIONS
Content-Type: application/vnd.api+json
Vary: Accept

{
    "data": {
        "type": "GeneCombination",
        "id": "370",
        "attributes": {
            "gene_relationship": [
                "Involved in the same disease",
                "Relevant pathways for phenotype"
            ],
            "protein_interactions": [],
            "common_pathways": [
                "Ras signaling pathway",
                "Breast cancer",
                "Central carbon metabolism in cancer",
                "Melanoma",
                "Disease",
                "Calcium signaling pathway",
                "Proteoglycans in cancer",
                "Diseases of signal transduction by growth factor receptors and second messengers",
                "secretion and action",
                "Pathways in cancer",
                "Parathyroid hormone synthesis",
                "Regulation of actin cytoskeleton",
                "Rap1 signaling pathway",
                "PI3K-Akt signaling pathway",
                "Adherens junction",
                "Prostate cancer"
            ],
            "genecomb_metascore": 2,
            "lastmodified": "2021-10-18T11:01:04.964838"
        },
        "relationships": {
            "combination_set": {
                "meta": {
                    "count": 1
                },
                "data": [
                    {
                        "type": "Combination",
                        "id": "OLI554"
                    }
                ],
                "links": {
                    "self": "https://olida.ibsquare.be/api/genecombinations/370/relationships/combination_set?format=api",
                    "related": "https://olida.ibsquare.be/api/genecombinations/370/combinations/?format=api"
                }
            },
            "genes": {
                "meta": {
                    "count": 3
                },
                "data": [
                    {
                        "type": "Gene",
                        "id": "EGFR"
                    },
                    {
                        "type": "Gene",
                        "id": "FGFR1"
                    },
                    {
                        "type": "Gene",
                        "id": "MDGA1"
                    }
                ],
                "links": {
                    "self": "https://olida.ibsquare.be/api/genecombinations/370/relationships/genes?format=api",
                    "related": "https://olida.ibsquare.be/api/genecombinations/370/genes/?format=api"
                }
            }
        },
        "links": {
            "self": "https://olida.ibsquare.be/api/genecombinations/370/?format=api"
        }
    }
}