Gene Combination Instance – Django REST framework

This API endpoint handles listing (/references) and retrieval (/references/<ID>/) of References from the database
that support the inclusion of at least one oligogenic combination in OLIDA.

GET /api/genecombinations/366/?format=api

HTTP 200 OK
Allow: GET, HEAD, OPTIONS
Content-Type: application/vnd.api+json
Vary: Accept

{
    "data": {
        "type": "GeneCombination",
        "id": "366",
        "attributes": {
            "gene_relationship": [
                "Directly interacting",
                "Same protein complex",
                "Involved in the same disease",
                "Affecting the same tissue",
                "Relevant pathways for phenotype",
                "Same pathway"
            ],
            "protein_interactions": [
                "(KCNE1, KCNH2)",
                "(KCNE1, KCNQ1)"
            ],
            "common_pathways": [
                "Muscle contraction",
                "Voltage gated Potassium channels",
                "Phase 3 - rapid repolarisation",
                "Neuronal System",
                "Phase 2 - plateau phase",
                "Cardiac conduction",
                "Adrenergic signaling in cardiomyocytes"
            ],
            "genecomb_metascore": 2,
            "lastmodified": "2021-10-18T11:01:04.769938"
        },
        "relationships": {
            "combination_set": {
                "meta": {
                    "count": 1
                },
                "data": [
                    {
                        "type": "Combination",
                        "id": "OLI549"
                    }
                ],
                "links": {
                    "self": "https://olida.ibsquare.be/api/genecombinations/366/relationships/combination_set?format=api",
                    "related": "https://olida.ibsquare.be/api/genecombinations/366/combinations/?format=api"
                }
            },
            "genes": {
                "meta": {
                    "count": 3
                },
                "data": [
                    {
                        "type": "Gene",
                        "id": "KCNE1"
                    },
                    {
                        "type": "Gene",
                        "id": "KCNH2"
                    },
                    {
                        "type": "Gene",
                        "id": "KCNQ1"
                    }
                ],
                "links": {
                    "self": "https://olida.ibsquare.be/api/genecombinations/366/relationships/genes?format=api",
                    "related": "https://olida.ibsquare.be/api/genecombinations/366/genes/?format=api"
                }
            }
        },
        "links": {
            "self": "https://olida.ibsquare.be/api/genecombinations/366/?format=api"
        }
    }
}