Gene List
This API endpoint handles listing (/genes) and retrieval (/genes/<ID>/) of genes that are contained in the database due to their association to
genetic variants that are involved in at least one oligogenic combination in OLIDA.
GET /api/genecombinations/36/genes/?format=api
{ "data": [ { "type": "Gene", "id": "PRF1", "attributes": { "go_molecular_function": [ "identical protein binding", "protein binding", "calcium ion binding" ], "pathway_id": [ "kegg_path:hsa05332", "kegg_path:hsa04650", "kegg_path:hsa04210", "kegg_path:hsa05320", "kegg_path:hsa04940", "kegg_path:hsa05330", "kegg_path:hsa05416" ], "essential_gene": "Non-essential", "status": "CU", "uniprot_acc": "P14222", "ensembl_id": "ENSG00000180644", "entrez_id": "5551", "chromosome_number": "10", "lastmodified": "2021-10-18T11:00:44.475822" }, "relationships": { "variant_set": { "meta": { "count": 12 }, "data": [ { "type": "SmallVariant", "id": "102" }, { "type": "SmallVariant", "id": "103" }, { "type": "SmallVariant", "id": "111" }, { "type": "SmallVariant", "id": "116" }, { "type": "SmallVariant", "id": "1106" }, { "type": "SmallVariant", "id": "1108" }, { "type": "SmallVariant", "id": "1110" }, { "type": "SmallVariant", "id": "1115" }, { "type": "SmallVariant", "id": "1118" }, { "type": "SmallVariant", "id": "1121" }, { "type": "SmallVariant", "id": "1123" }, { "type": "SmallVariant", "id": "1126" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/PRF1/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/genes/PRF1/variants/?format=api" } }, "genecombination_set": { "meta": { "count": 3 }, "data": [ { "type": "GeneCombination", "id": "36" }, { "type": "GeneCombination", "id": "39" }, { "type": "GeneCombination", "id": "41" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/PRF1/relationships/genecombination_set?format=api", "related": "https://olida.ibsquare.be/api/genes/PRF1/genecombinations/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genes/PRF1/?format=api" } }, { "type": "Gene", "id": "STX11", "attributes": { "go_molecular_function": [ "SNAP receptor activity", "protein binding", "SNARE binding" ], "pathway_id": [ "kegg_path:hsa04130" ], "essential_gene": null, "status": "CU", "uniprot_acc": "O75558", "ensembl_id": "ENSG00000135604", "entrez_id": "8676", "chromosome_number": "6", "lastmodified": "2021-10-18T11:00:44.788689" }, "relationships": { "variant_set": { "meta": { "count": 4 }, "data": [ { "type": "SmallVariant", "id": "104" }, { "type": "SmallVariant", "id": "1136" }, { "type": "SmallVariant", "id": "1138" }, { "type": "SmallVariant", "id": "2124" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/STX11/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/genes/STX11/variants/?format=api" } }, "genecombination_set": { "meta": { "count": 3 }, "data": [ { "type": "GeneCombination", "id": "36" }, { "type": "GeneCombination", "id": "362" }, { "type": "GeneCombination", "id": "363" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/STX11/relationships/genecombination_set?format=api", "related": "https://olida.ibsquare.be/api/genes/STX11/genecombinations/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genes/STX11/?format=api" } } ], "meta": { "database_name": "OLIgogenic diseases DAtabase (OLIDA)", "resource_url": "olida.ibsquare.be", "api_release_year": "2021", "api_developer": [ [ "Arnau Dillen", "arnau.dillen@ulb.ac.be" ], [ "Charlotte Nachtegael", "charlotte.nachtegael@ulb.be" ] ], "api_version": "0.3", "api_maintainers": [ [ "Charlotte Nachtegael", "charlotte.nachtegael@ulb.be" ] ], "api_documentation": [ "olida.ibsquare.be/api/swagger", "olida.ibsquare.be/api/redoc" ], "copyright": "Copyright (c) 2024 · OLIDA All Rights Reserved.", "license": "CC Attribution-NonCommercial 4.0 International License", "ontologies": { "ORDO": "http://bioportal.bioontology.org/ontologies/ORDO", "GENO": "http://purl.obolibrary.org/obo/geno.owl", "MI": "http://purl.obolibrary.org/obo/mi.owl", "NCIT": "http://purl.obolibrary.org/obo/ncit.owl", "OGI": "http://purl.obolibrary.org/obo/ogi.owl", "OGG": "http://purl.obolibrary.org/obo/ogg.owl" }, "relevant_publications_doi": [ "10.1093/nar/gkv1068", "10.1093/database/baac023" ], "size": 2 } }