Gene List
This API endpoint handles listing (/genes) and retrieval (/genes/<ID>/) of genes that are contained in the database due to their association to
genetic variants that are involved in at least one oligogenic combination in OLIDA.
GET /api/genecombinations/358/genes/?format=api
{ "data": [ { "type": "Gene", "id": "CLCN7", "attributes": { "go_molecular_function": [ "protein binding", "nucleotide binding", "ATP binding", "chloride channel activity", "antiporter activity", "chloride transmembrane transporter activity" ], "pathway_id": [ "R-HSA-382551", "R-HSA-983712", "R-HSA-2672351" ], "essential_gene": "Essential", "status": "CU", "uniprot_acc": "P51798", "ensembl_id": "ENSG00000103249", "entrez_id": "1186", "chromosome_number": "16", "lastmodified": "2021-10-18T11:00:44.422329" }, "relationships": { "variant_set": { "meta": { "count": 1 }, "data": [ { "type": "SmallVariant", "id": "1092" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/CLCN7/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/genes/CLCN7/variants/?format=api" } }, "genecombination_set": { "meta": { "count": 1 }, "data": [ { "type": "GeneCombination", "id": "358" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/CLCN7/relationships/genecombination_set?format=api", "related": "https://olida.ibsquare.be/api/genes/CLCN7/genecombinations/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genes/CLCN7/?format=api" } }, { "type": "Gene", "id": "TCIRG1", "attributes": { "go_molecular_function": [ "['ATPase binding', 'transporter activity', 'protein binding', 'proton transmembrane transporter activity']" ], "pathway_id": [ "kegg_path:hsa00190", "kegg_path:hsa01100", "kegg_path:hsa04142", "kegg_path:hsa04145", "kegg_path:hsa04721", "kegg_path:hsa04966", "kegg_path:hsa05110", "kegg_path:hsa05120", "kegg_path:hsa05152", "kegg_path:hsa05165", "kegg_path:hsa05323", "kegg_path:hsa00190", "kegg_path:hsa01100", "kegg_path:hsa04142", "kegg_path:hsa04145", "kegg_path:hsa04721", "kegg_path:hsa04966", "kegg_path:hsa05110", "kegg_path:hsa05120", "kegg_path:hsa05152", "kegg_path:hsa05165", "kegg_path:hsa05323", "R-HSA-1222556", "R-HSA-162582", "R-HSA-168249", "R-HSA-168256", "R-HSA-2262752", "R-HSA-382551", "R-HSA-6798695", "R-HSA-74752", "R-HSA-77387", "R-HSA-8953897", "R-HSA-9006934", "R-HSA-917937", "R-HSA-917977", "R-HSA-9639288", "R-HSA-983712" ], "essential_gene": "Essential", "status": "CU", "uniprot_acc": "Q13488", "ensembl_id": "None", "entrez_id": "ENSG00000110719", "chromosome_number": "11", "lastmodified": "2021-10-18T11:00:44.321685" }, "relationships": { "variant_set": { "meta": { "count": 2 }, "data": [ { "type": "SmallVariant", "id": "1091" }, { "type": "SmallVariant", "id": "3640" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/TCIRG1/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/genes/TCIRG1/variants/?format=api" } }, "genecombination_set": { "meta": { "count": 2 }, "data": [ { "type": "GeneCombination", "id": "358" }, { "type": "GeneCombination", "id": "1225" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/TCIRG1/relationships/genecombination_set?format=api", "related": "https://olida.ibsquare.be/api/genes/TCIRG1/genecombinations/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genes/TCIRG1/?format=api" } } ], "meta": { "database_name": "OLIgogenic diseases DAtabase (OLIDA)", "resource_url": "olida.ibsquare.be", "api_release_year": "2021", "api_developer": [ [ "Arnau Dillen", "arnau.dillen@ulb.ac.be" ], [ "Charlotte Nachtegael", "charlotte.nachtegael@ulb.be" ] ], "api_version": "0.3", "api_maintainers": [ [ "Charlotte Nachtegael", "charlotte.nachtegael@ulb.be" ] ], "api_documentation": [ "olida.ibsquare.be/api/swagger", "olida.ibsquare.be/api/redoc" ], "copyright": "Copyright (c) 2025 · OLIDA All Rights Reserved.", "license": "CC Attribution-NonCommercial 4.0 International License", "ontologies": { "ORDO": "http://bioportal.bioontology.org/ontologies/ORDO", "GENO": "http://purl.obolibrary.org/obo/geno.owl", "MI": "http://purl.obolibrary.org/obo/mi.owl", "NCIT": "http://purl.obolibrary.org/obo/ncit.owl", "OGI": "http://purl.obolibrary.org/obo/ogi.owl", "OGG": "http://purl.obolibrary.org/obo/ogg.owl" }, "relevant_publications_doi": [ "10.1093/nar/gkv1068", "10.1093/database/baac023" ], "size": 2 } }