Gene List
This API endpoint handles listing (/genes) and retrieval (/genes/<ID>/) of genes that are contained in the database due to their association to
genetic variants that are involved in at least one oligogenic combination in OLIDA.
GET /api/genecombinations/357/genes/?format=api
{ "data": [ { "type": "Gene", "id": "C3", "attributes": { "go_molecular_function": [ "protein binding", "signaling receptor binding" ], "pathway_id": [ "kegg_path:hsa05168", "kegg_path:hsa05203", "kegg_path:hsa04080", "kegg_path:hsa05150", "R-HSA-6798695", "kegg_path:hsa05142", "kegg_path:hsa05322", "kegg_path:hsa05140", "R-HSA-597592", "R-HSA-375276", "R-HSA-9660826", "kegg_path:hsa04613", "R-HSA-162582", "R-HSA-173736", "R-HSA-372790", "kegg_path:hsa05171", "R-HSA-166658", "R-HSA-500792", "R-HSA-8957275", "kegg_path:hsa04145", "kegg_path:hsa05167", "kegg_path:hsa04610", "R-HSA-198933", "R-HSA-174577", "R-HSA-1643685", "R-HSA-381426", "R-HSA-388396", "kegg_path:hsa05152", "R-HSA-1280218", "R-HSA-168249", "R-HSA-392499", "kegg_path:hsa05134", "R-HSA-977606", "R-HSA-168256", "R-HSA-9664424", "R-HSA-373076", "R-HSA-418594", "R-HSA-5663205", "R-HSA-9658195", "kegg_path:hsa05131", "kegg_path:hsa05133", "R-HSA-166663" ], "essential_gene": "Non-essential", "status": "CU", "uniprot_acc": "P01024", "ensembl_id": "ENSG00000125730", "entrez_id": "718", "chromosome_number": "19", "lastmodified": "2021-10-18T11:00:44.497190" }, "relationships": { "variant_set": { "meta": { "count": 1 }, "data": [ { "type": "SmallVariant", "id": "1089" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/C3/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/genes/C3/variants/?format=api" } }, "genecombination_set": { "meta": { "count": 1 }, "data": [ { "type": "GeneCombination", "id": "357" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/C3/relationships/genecombination_set?format=api", "related": "https://olida.ibsquare.be/api/genes/C3/genecombinations/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genes/C3/?format=api" } }, { "type": "Gene", "id": "CD46", "attributes": { "go_molecular_function": [ "signaling receptor activity", "protein binding", "virus receptor activity" ], "pathway_id": [ "R-HSA-977606", "R-HSA-168256", "R-HSA-166658", "R-HSA-168249", "kegg_path:hsa05162", "kegg_path:hsa04610" ], "essential_gene": "Non-essential", "status": "CU", "uniprot_acc": "P15529", "ensembl_id": "ENSG00000117335", "entrez_id": "4179", "chromosome_number": "1", "lastmodified": "2021-10-18T11:00:44.548051" }, "relationships": { "variant_set": { "meta": { "count": 1 }, "data": [ { "type": "SmallVariant", "id": "1090" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/CD46/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/genes/CD46/variants/?format=api" } }, "genecombination_set": { "meta": { "count": 1 }, "data": [ { "type": "GeneCombination", "id": "357" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/CD46/relationships/genecombination_set?format=api", "related": "https://olida.ibsquare.be/api/genes/CD46/genecombinations/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genes/CD46/?format=api" } } ], "meta": { "database_name": "OLIgogenic diseases DAtabase (OLIDA)", "resource_url": "olida.ibsquare.be", "api_release_year": "2021", "api_developer": [ [ "Arnau Dillen", "arnau.dillen@ulb.ac.be" ], [ "Charlotte Nachtegael", "charlotte.nachtegael@ulb.be" ] ], "api_version": "0.3", "api_maintainers": [ [ "Charlotte Nachtegael", "charlotte.nachtegael@ulb.be" ] ], "api_documentation": [ "olida.ibsquare.be/api/swagger", "olida.ibsquare.be/api/redoc" ], "copyright": "Copyright (c) 2025 · OLIDA All Rights Reserved.", "license": "CC Attribution-NonCommercial 4.0 International License", "ontologies": { "ORDO": "http://bioportal.bioontology.org/ontologies/ORDO", "GENO": "http://purl.obolibrary.org/obo/geno.owl", "MI": "http://purl.obolibrary.org/obo/mi.owl", "NCIT": "http://purl.obolibrary.org/obo/ncit.owl", "OGI": "http://purl.obolibrary.org/obo/ogi.owl", "OGG": "http://purl.obolibrary.org/obo/ogg.owl" }, "relevant_publications_doi": [ "10.1093/nar/gkv1068", "10.1093/database/baac023" ], "size": 2 } }