Gene List
This API endpoint handles listing (/genes) and retrieval (/genes/<ID>/) of genes that are contained in the database due to their association to
genetic variants that are involved in at least one oligogenic combination in OLIDA.
GET /api/genecombinations/34/genes/?format=api
{ "data": [ { "type": "Gene", "id": "CNGA3", "attributes": { "go_molecular_function": [ "intracellular cGMP-activated cation channel activity", "protein C-terminus binding", "protein binding", "nucleotide binding", "ligand-gated ion channel activity", "cGMP binding", "ion channel activity", "intracellular cAMP-activated cation channel activity" ], "pathway_id": [ "kegg_path:hsa04024", "kegg_path:hsa04740" ], "essential_gene": "Non-essential", "status": "CU", "uniprot_acc": "Q16281", "ensembl_id": "ENSG00000144191", "entrez_id": "1261", "chromosome_number": "2", "lastmodified": "2021-10-18T11:00:44.452666" }, "relationships": { "variant_set": { "meta": { "count": 9 }, "data": [ { "type": "SmallVariant", "id": "88" }, { "type": "SmallVariant", "id": "89" }, { "type": "SmallVariant", "id": "90" }, { "type": "SmallVariant", "id": "91" }, { "type": "SmallVariant", "id": "93" }, { "type": "SmallVariant", "id": "94" }, { "type": "SmallVariant", "id": "96" }, { "type": "SmallVariant", "id": "97" }, { "type": "SmallVariant", "id": "99" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/CNGA3/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/genes/CNGA3/variants/?format=api" } }, "genecombination_set": { "meta": { "count": 1 }, "data": [ { "type": "GeneCombination", "id": "34" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/CNGA3/relationships/genecombination_set?format=api", "related": "https://olida.ibsquare.be/api/genes/CNGA3/genecombinations/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genes/CNGA3/?format=api" } }, { "type": "Gene", "id": "CNGB3", "attributes": { "go_molecular_function": [ "intracellular cGMP-activated cation channel activity", "nucleotide binding", "cGMP binding", "intracellular cAMP-activated cation channel activity" ], "pathway_id": [ "kegg_path:hsa04024" ], "essential_gene": "Non-essential", "status": "CU", "uniprot_acc": "Q9NQW8", "ensembl_id": "ENSG00000170289", "entrez_id": "54714", "chromosome_number": "8", "lastmodified": "2021-10-18T11:00:44.889378" }, "relationships": { "variant_set": { "meta": { "count": 4 }, "data": [ { "type": "SmallVariant", "id": "87" }, { "type": "SmallVariant", "id": "92" }, { "type": "SmallVariant", "id": "95" }, { "type": "SmallVariant", "id": "98" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/CNGB3/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/genes/CNGB3/variants/?format=api" } }, "genecombination_set": { "meta": { "count": 1 }, "data": [ { "type": "GeneCombination", "id": "34" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/CNGB3/relationships/genecombination_set?format=api", "related": "https://olida.ibsquare.be/api/genes/CNGB3/genecombinations/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genes/CNGB3/?format=api" } } ], "meta": { "database_name": "OLIgogenic diseases DAtabase (OLIDA)", "resource_url": "olida.ibsquare.be", "api_release_year": "2021", "api_developer": [ [ "Arnau Dillen", "arnau.dillen@ulb.ac.be" ], [ "Charlotte Nachtegael", "charlotte.nachtegael@ulb.be" ] ], "api_version": "0.3", "api_maintainers": [ [ "Charlotte Nachtegael", "charlotte.nachtegael@ulb.be" ] ], "api_documentation": [ "olida.ibsquare.be/api/swagger", "olida.ibsquare.be/api/redoc" ], "copyright": "Copyright (c) 2025 · OLIDA All Rights Reserved.", "license": "CC Attribution-NonCommercial 4.0 International License", "ontologies": { "ORDO": "http://bioportal.bioontology.org/ontologies/ORDO", "GENO": "http://purl.obolibrary.org/obo/geno.owl", "MI": "http://purl.obolibrary.org/obo/mi.owl", "NCIT": "http://purl.obolibrary.org/obo/ncit.owl", "OGI": "http://purl.obolibrary.org/obo/ogi.owl", "OGG": "http://purl.obolibrary.org/obo/ogg.owl" }, "relevant_publications_doi": [ "10.1093/nar/gkv1068", "10.1093/database/baac023" ], "size": 2 } }