Gene Combination Instance – Django REST framework

This API endpoint handles listing (/references) and retrieval (/references/<ID>/) of References from the database
that support the inclusion of at least one oligogenic combination in OLIDA.

GET /api/genecombinations/334/?format=api

HTTP 200 OK
Allow: GET, HEAD, OPTIONS
Content-Type: application/vnd.api+json
Vary: Accept

{
    "data": {
        "type": "GeneCombination",
        "id": "334",
        "attributes": {
            "gene_relationship": [
                "Involved in the same disease",
                "Directly interacting",
                "Same pathway"
            ],
            "protein_interactions": [
                "(TSC1, TSC2)"
            ],
            "common_pathways": [
                "Gene expression (Transcription)",
                "Macroautophagy",
                "Generic Transcription Pathway",
                "AMPK signaling pathway",
                "Autophagy",
                "Autophagy - animal",
                "Choline metabolism in cancer",
                "Inhibition of TSC complex formation by PKB",
                "RNA Polymerase II Transcription",
                "TBC/RABGAPs",
                "Insulin signaling pathway",
                "Herpes simplex virus 1 infection",
                "Transcriptional Regulation by TP53",
                "MTOR signalling",
                "Membrane Trafficking",
                "Longevity regulating pathway",
                "Vesicle-mediated transport",
                "Phospholipase D signaling pathway",
                "Rab regulation of trafficking",
                "TP53 Regulates Metabolic Genes",
                "mTOR signaling pathway",
                "Human cytomegalovirus infection",
                "Cellular senescence",
                "Human papillomavirus infection",
                "PI3K-Akt signaling pathway",
                "Thermogenesis",
                "Signal Transduction"
            ],
            "genecomb_metascore": 2,
            "lastmodified": "2021-10-18T11:01:02.838704"
        },
        "relationships": {
            "combination_set": {
                "meta": {
                    "count": 1
                },
                "data": [
                    {
                        "type": "Combination",
                        "id": "OLI485"
                    }
                ],
                "links": {
                    "self": "https://olida.ibsquare.be/api/genecombinations/334/relationships/combination_set?format=api",
                    "related": "https://olida.ibsquare.be/api/genecombinations/334/combinations/?format=api"
                }
            },
            "genes": {
                "meta": {
                    "count": 2
                },
                "data": [
                    {
                        "type": "Gene",
                        "id": "TSC1"
                    },
                    {
                        "type": "Gene",
                        "id": "TSC2"
                    }
                ],
                "links": {
                    "self": "https://olida.ibsquare.be/api/genecombinations/334/relationships/genes?format=api",
                    "related": "https://olida.ibsquare.be/api/genecombinations/334/genes/?format=api"
                }
            }
        },
        "links": {
            "self": "https://olida.ibsquare.be/api/genecombinations/334/?format=api"
        }
    }
}