Combination List
This API endpoint handles listing (/combinations) and retrieval (/combinations/{combination_pk}/) of oligogenic combinations from the database
GET /api/genecombinations/322/combinations/?format=api
{ "data": [ { "type": "Combination", "id": "OLI469", "attributes": { "scores": { "familial_evidence": 0, "statistical_evidence_manual": 1, "statistical_evidence_knowledge": 0, "statistical_evidence_metascore": 1, "functional_gene_evidence_manual": 2, "functional_gene_evidence_manual_harmonized": 2, "functional_gene_evidence_knowledge": 0, "functional_gene_evidence_metascore": 2, "functional_variant_evidence_manual": 0, "functional_variant_evidence_knowledge": 0, "functional_variant_evidence_metascore": 0, "functional_final_manual": 0, "functional_final_metascore": 0, "final_manual": 0, "final_metascore": 0 }, "omim_id": [], "oligogenic_effect": "Unknown", "status": "CU", "effect_predicted": false, "ethnicity": "East Asian", "lastmodified": "2021-11-16T17:59:45.996118" }, "relationships": { "diseases": { "meta": { "count": 1 }, "data": [ { "type": "Disease", "id": "442" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI469/relationships/diseases?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI469/diseases/?format=api" } }, "variant_set": { "meta": { "count": 4 }, "data": [ { "type": "SmallVariant", "id": "1004" }, { "type": "SmallVariant", "id": "1006" }, { "type": "SmallVariant", "id": "1007" }, { "type": "SmallVariant", "id": "1008" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI469/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI469/variants/?format=api" } }, "reference_set": { "meta": { "count": 1 }, "data": [ { "type": "Reference", "id": "861" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI469/relationships/reference_set?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI469/references/?format=api" } }, "gene_combination": { "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI469/relationships/gene_combination?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI469/genecombinations/?format=api" }, "data": { "type": "GeneCombination", "id": "322" } } }, "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI469/?format=api" } }, { "type": "Combination", "id": "OLI519", "attributes": { "scores": { "familial_evidence": 0, "statistical_evidence_manual": 0, "statistical_evidence_knowledge": 0, "statistical_evidence_metascore": 0, "functional_gene_evidence_manual": 1, "functional_gene_evidence_manual_harmonized": 2, "functional_gene_evidence_knowledge": 0, "functional_gene_evidence_metascore": 2, "functional_variant_evidence_manual": 1, "functional_variant_evidence_knowledge": 1, "functional_variant_evidence_metascore": 1, "functional_final_manual": 1, "functional_final_metascore": 2, "final_manual": 0, "final_metascore": 0 }, "omim_id": [], "oligogenic_effect": "Unknown", "status": "CU", "effect_predicted": false, "ethnicity": "Unknown", "lastmodified": "2021-11-16T17:59:46.833622" }, "relationships": { "diseases": { "meta": { "count": 1 }, "data": [ { "type": "Disease", "id": "442" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI519/relationships/diseases?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI519/diseases/?format=api" } }, "variant_set": { "meta": { "count": 2 }, "data": [ { "type": "SmallVariant", "id": "1100" }, { "type": "SmallVariant", "id": "1101" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI519/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI519/variants/?format=api" } }, "reference_set": { "meta": { "count": 1 }, "data": [ { "type": "Reference", "id": "682" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI519/relationships/reference_set?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI519/references/?format=api" } }, "gene_combination": { "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI519/relationships/gene_combination?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI519/genecombinations/?format=api" }, "data": { "type": "GeneCombination", "id": "322" } } }, "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI519/?format=api" } }, { "type": "Combination", "id": "OLI587", "attributes": { "scores": { "familial_evidence": 0, "statistical_evidence_manual": 0, "statistical_evidence_knowledge": 0, "statistical_evidence_metascore": 0, "functional_gene_evidence_manual": 0, "functional_gene_evidence_manual_harmonized": 2, "functional_gene_evidence_knowledge": 0, "functional_gene_evidence_metascore": 2, "functional_variant_evidence_manual": 0, "functional_variant_evidence_knowledge": 0, "functional_variant_evidence_metascore": 0, "functional_final_manual": 0, "functional_final_metascore": 0, "final_manual": 0, "final_metascore": 0 }, "omim_id": [], "oligogenic_effect": "Unknown", "status": "CU", "effect_predicted": false, "ethnicity": "European/Caucasian", "lastmodified": "2021-11-16T17:59:48.116603" }, "relationships": { "diseases": { "meta": { "count": 1 }, "data": [ { "type": "Disease", "id": "442" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI587/relationships/diseases?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI587/diseases/?format=api" } }, "variant_set": { "meta": { "count": 2 }, "data": [ { "type": "SmallVariant", "id": "1247" }, { "type": "SmallVariant", "id": "1248" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI587/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI587/variants/?format=api" } }, "reference_set": { "meta": { "count": 1 }, "data": [ { "type": "Reference", "id": "799" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI587/relationships/reference_set?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI587/references/?format=api" } }, "gene_combination": { "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI587/relationships/gene_combination?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI587/genecombinations/?format=api" }, "data": { "type": "GeneCombination", "id": "322" } } }, "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI587/?format=api" } }, { "type": "Combination", "id": "OLI995", "attributes": { "scores": { "familial_evidence": 0, "statistical_evidence_manual": 1, "statistical_evidence_knowledge": 0, "statistical_evidence_metascore": 1, "functional_gene_evidence_manual": 2, "functional_gene_evidence_manual_harmonized": 2, "functional_gene_evidence_knowledge": 0, "functional_gene_evidence_metascore": 2, "functional_variant_evidence_manual": 0, "functional_variant_evidence_knowledge": 0, "functional_variant_evidence_metascore": 0, "functional_final_manual": 0, "functional_final_metascore": 0, "final_manual": 0, "final_metascore": 0 }, "omim_id": [], "oligogenic_effect": "Unknown", "status": "CU", "effect_predicted": false, "ethnicity": "Unknown", "lastmodified": "2022-08-04T14:15:18.871086" }, "relationships": { "diseases": { "meta": { "count": 1 }, "data": [ { "type": "Disease", "id": "442" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI995/relationships/diseases?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI995/diseases/?format=api" } }, "variant_set": { "meta": { "count": 2 }, "data": [ { "type": "SmallVariant", "id": "2157" }, { "type": "SmallVariant", "id": "2158" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI995/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI995/variants/?format=api" } }, "reference_set": { "meta": { "count": 1 }, "data": [ { "type": "Reference", "id": "891" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI995/relationships/reference_set?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI995/references/?format=api" } }, "gene_combination": { "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI995/relationships/gene_combination?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI995/genecombinations/?format=api" }, "data": { "type": "GeneCombination", "id": "322" } } }, "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI995/?format=api" } }, { "type": "Combination", "id": "OLI1025", "attributes": { "scores": { "familial_evidence": 0, "statistical_evidence_manual": 1, "statistical_evidence_knowledge": 0, "statistical_evidence_metascore": 1, "functional_gene_evidence_manual": 1, "functional_gene_evidence_manual_harmonized": 2, "functional_gene_evidence_knowledge": 0, "functional_gene_evidence_metascore": 2, "functional_variant_evidence_manual": 1, "functional_variant_evidence_knowledge": 1, "functional_variant_evidence_metascore": 1, "functional_final_manual": 1, "functional_final_metascore": 2, "final_manual": 0, "final_metascore": 1 }, "omim_id": [], "oligogenic_effect": "Unknown", "status": "CU", "effect_predicted": false, "ethnicity": "Mixed", "lastmodified": "2022-08-04T14:15:22.988989" }, "relationships": { "diseases": { "meta": { "count": 1 }, "data": [ { "type": "Disease", "id": "442" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI1025/relationships/diseases?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI1025/diseases/?format=api" } }, "variant_set": { "meta": { "count": 2 }, "data": [ { "type": "SmallVariant", "id": "2211" }, { "type": "SmallVariant", "id": "2218" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI1025/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI1025/variants/?format=api" } }, "reference_set": { "meta": { "count": 1 }, "data": [ { "type": "Reference", "id": "899" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI1025/relationships/reference_set?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI1025/references/?format=api" } }, "gene_combination": { "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI1025/relationships/gene_combination?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI1025/genecombinations/?format=api" }, "data": { "type": "GeneCombination", "id": "322" } } }, "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI1025/?format=api" } }, { "type": "Combination", "id": "OLI1026", "attributes": { "scores": { "familial_evidence": 0, "statistical_evidence_manual": 1, "statistical_evidence_knowledge": 0, "statistical_evidence_metascore": 1, "functional_gene_evidence_manual": 1, "functional_gene_evidence_manual_harmonized": 2, "functional_gene_evidence_knowledge": 0, "functional_gene_evidence_metascore": 2, "functional_variant_evidence_manual": 1, "functional_variant_evidence_knowledge": 1, "functional_variant_evidence_metascore": 1, "functional_final_manual": 1, "functional_final_metascore": 2, "final_manual": 0, "final_metascore": 1 }, "omim_id": [], "oligogenic_effect": "Unknown", "status": "CU", "effect_predicted": false, "ethnicity": "Mixed", "lastmodified": "2022-08-04T14:15:23.114005" }, "relationships": { "diseases": { "meta": { "count": 1 }, "data": [ { "type": "Disease", "id": "442" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI1026/relationships/diseases?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI1026/diseases/?format=api" } }, "variant_set": { "meta": { "count": 2 }, "data": [ { "type": "SmallVariant", "id": "2219" }, { "type": "SmallVariant", "id": "2220" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI1026/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI1026/variants/?format=api" } }, "reference_set": { "meta": { "count": 1 }, "data": [ { "type": "Reference", "id": "899" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI1026/relationships/reference_set?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI1026/references/?format=api" } }, "gene_combination": { "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI1026/relationships/gene_combination?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI1026/genecombinations/?format=api" }, "data": { "type": "GeneCombination", "id": "322" } } }, "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI1026/?format=api" } } ], "meta": { "database_name": "OLIgogenic diseases DAtabase (OLIDA)", "resource_url": "olida.ibsquare.be", "api_release_year": "2021", "api_developer": [ [ "Arnau Dillen", "arnau.dillen@ulb.ac.be" ], [ "Charlotte Nachtegael", "charlotte.nachtegael@ulb.be" ] ], "api_version": "0.3", "api_maintainers": [ [ "Charlotte Nachtegael", "charlotte.nachtegael@ulb.be" ] ], "api_documentation": [ "olida.ibsquare.be/api/swagger", "olida.ibsquare.be/api/redoc" ], "copyright": "Copyright (c) 2025 · OLIDA All Rights Reserved.", "license": "CC Attribution-NonCommercial 4.0 International License", "ontologies": { "ORDO": "http://bioportal.bioontology.org/ontologies/ORDO", "GENO": "http://purl.obolibrary.org/obo/geno.owl", "MI": "http://purl.obolibrary.org/obo/mi.owl", "NCIT": "http://purl.obolibrary.org/obo/ncit.owl", "OGI": "http://purl.obolibrary.org/obo/ogi.owl", "OGG": "http://purl.obolibrary.org/obo/ogg.owl" }, "relevant_publications_doi": [ "10.1093/nar/gkv1068", "10.1093/database/baac023" ], "size": 6 } }