Gene Combination Instance – Django REST framework

This API endpoint handles listing (/references) and retrieval (/references/<ID>/) of References from the database
that support the inclusion of at least one oligogenic combination in OLIDA.

GET /api/genecombinations/317/?format=api

HTTP 200 OK
Allow: GET, HEAD, OPTIONS
Content-Type: application/vnd.api+json
Vary: Accept

{
    "data": {
        "type": "GeneCombination",
        "id": "317",
        "attributes": {
            "gene_relationship": [
                "Involved in the same disease",
                "Same pathway",
                "Relevant pathways for phenotype"
            ],
            "protein_interactions": [
                "(APOB, MTTP)"
            ],
            "common_pathways": [
                "Post-translational protein phosphorylation",
                "and clearance",
                "Plasma lipoprotein assembly",
                "Fat digestion and absorption",
                "Transport of small molecules",
                "Metabolism of proteins",
                "Plasma lipoprotein clearance",
                "Chylomicron assembly",
                "Cholesterol metabolism",
                "Membrane Trafficking",
                "Immune System",
                "Vesicle-mediated transport",
                "Post-translational protein modification",
                "Plasma lipoprotein remodeling",
                "Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)",
                "Plasma lipoprotein assembly",
                "remodeling",
                "Metabolism",
                "LDL clearance",
                "Signal Transduction"
            ],
            "genecomb_metascore": 2,
            "lastmodified": "2021-10-18T11:01:02.070003"
        },
        "relationships": {
            "combination_set": {
                "meta": {
                    "count": 1
                },
                "data": [
                    {
                        "type": "Combination",
                        "id": "OLI463"
                    }
                ],
                "links": {
                    "self": "https://olida.ibsquare.be/api/genecombinations/317/relationships/combination_set?format=api",
                    "related": "https://olida.ibsquare.be/api/genecombinations/317/combinations/?format=api"
                }
            },
            "genes": {
                "meta": {
                    "count": 5
                },
                "data": [
                    {
                        "type": "Gene",
                        "id": "ANGPTL3"
                    },
                    {
                        "type": "Gene",
                        "id": "APOB"
                    },
                    {
                        "type": "Gene",
                        "id": "MTTP"
                    },
                    {
                        "type": "Gene",
                        "id": "PCSK9"
                    },
                    {
                        "type": "Gene",
                        "id": "SAR1B"
                    }
                ],
                "links": {
                    "self": "https://olida.ibsquare.be/api/genecombinations/317/relationships/genes?format=api",
                    "related": "https://olida.ibsquare.be/api/genecombinations/317/genes/?format=api"
                }
            }
        },
        "links": {
            "self": "https://olida.ibsquare.be/api/genecombinations/317/?format=api"
        }
    }
}