Gene List
This API endpoint handles listing (/genes) and retrieval (/genes/<ID>/) of genes that are contained in the database due to their association to
genetic variants that are involved in at least one oligogenic combination in OLIDA.
GET /api/genecombinations/284/genes/?format=api
{ "data": [ { "type": "Gene", "id": "PDE3A", "attributes": { "go_molecular_function": [ "protein binding", "hydrolase activity", "cGMP-inhibited cyclic-nucleotide phosphodiesterase activity", "3',5'-cyclic-nucleotide phosphodiesterase activity", "3',5'-cyclic-AMP phosphodiesterase activity", "metal ion binding" ], "pathway_id": [ "R-HSA-418555", "kegg_path:hsa04022", "kegg_path:hsa01100", "kegg_path:hsa04024", "kegg_path:hsa00230", "R-HSA-388396", "kegg_path:hsa04924", "kegg_path:hsa05032", "R-HSA-162582", "R-HSA-372790" ], "essential_gene": "Non-essential", "status": "CU", "uniprot_acc": "Q14432", "ensembl_id": "ENSG00000172572", "entrez_id": "5139", "chromosome_number": "12", "lastmodified": "2021-10-18T11:00:44.780939" }, "relationships": { "variant_set": { "meta": { "count": 1 }, "data": [ { "type": "SmallVariant", "id": "910" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/PDE3A/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/genes/PDE3A/variants/?format=api" } }, "genecombination_set": { "meta": { "count": 1 }, "data": [ { "type": "GeneCombination", "id": "284" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/PDE3A/relationships/genecombination_set?format=api", "related": "https://olida.ibsquare.be/api/genes/PDE3A/genecombinations/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genes/PDE3A/?format=api" } }, { "type": "Gene", "id": "TRAPPC9", "attributes": { "go_molecular_function": [ "protein binding" ], "pathway_id": [ "R-HSA-199977", "R-HSA-597592", "R-HSA-9007101", "R-HSA-392499", "R-HSA-8876198", "R-HSA-5653656", "R-HSA-204005", "R-HSA-199991", "R-HSA-948021", "R-HSA-446203" ], "essential_gene": null, "status": "CU", "uniprot_acc": "Q96Q05", "ensembl_id": "ENSG00000167632", "entrez_id": "83696", "chromosome_number": "8", "lastmodified": "2021-10-18T11:00:44.469386" }, "relationships": { "variant_set": { "meta": { "count": 2 }, "data": [ { "type": "SmallVariant", "id": "909" }, { "type": "SmallVariant", "id": "1856" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/TRAPPC9/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/genes/TRAPPC9/variants/?format=api" } }, "genecombination_set": { "meta": { "count": 2 }, "data": [ { "type": "GeneCombination", "id": "284" }, { "type": "GeneCombination", "id": "616" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/TRAPPC9/relationships/genecombination_set?format=api", "related": "https://olida.ibsquare.be/api/genes/TRAPPC9/genecombinations/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genes/TRAPPC9/?format=api" } } ], "meta": { "database_name": "OLIgogenic diseases DAtabase (OLIDA)", "resource_url": "olida.ibsquare.be", "api_release_year": "2021", "api_developer": [ [ "Arnau Dillen", "arnau.dillen@ulb.ac.be" ], [ "Charlotte Nachtegael", "charlotte.nachtegael@ulb.be" ] ], "api_version": "0.3", "api_maintainers": [ [ "Charlotte Nachtegael", "charlotte.nachtegael@ulb.be" ] ], "api_documentation": [ "olida.ibsquare.be/api/swagger", "olida.ibsquare.be/api/redoc" ], "copyright": "Copyright (c) 2025 · OLIDA All Rights Reserved.", "license": "CC Attribution-NonCommercial 4.0 International License", "ontologies": { "ORDO": "http://bioportal.bioontology.org/ontologies/ORDO", "GENO": "http://purl.obolibrary.org/obo/geno.owl", "MI": "http://purl.obolibrary.org/obo/mi.owl", "NCIT": "http://purl.obolibrary.org/obo/ncit.owl", "OGI": "http://purl.obolibrary.org/obo/ogi.owl", "OGG": "http://purl.obolibrary.org/obo/ogg.owl" }, "relevant_publications_doi": [ "10.1093/nar/gkv1068", "10.1093/database/baac023" ], "size": 2 } }