Gene List
This API endpoint handles listing (/genes) and retrieval (/genes/<ID>/) of genes that are contained in the database due to their association to
genetic variants that are involved in at least one oligogenic combination in OLIDA.
GET /api/genecombinations/282/genes/?format=api
{ "data": [ { "type": "Gene", "id": "AXL", "attributes": { "go_molecular_function": [ "['protein tyrosine kinase activity', 'myosin heavy chain binding', 'ATP binding', 'protein binding', 'phosphatidylserine binding', 'virus receptor activity', 'protein serine/threonine/tyrosine kinase activity', 'phosphatidylinositol 3-kinase binding', 'transmembrane receptor protein tyrosine kinase activity']" ], "pathway_id": [ "kegg_path:hsa01521", "R-HSA-162582", "R-HSA-194138", "R-HSA-4420097", "R-HSA-9006934" ], "essential_gene": "Non-essential", "status": "CU", "uniprot_acc": "P30530", "ensembl_id": "None", "entrez_id": "ENSG00000167601", "chromosome_number": "19", "lastmodified": "2021-10-18T11:00:44.989492" }, "relationships": { "variant_set": { "meta": { "count": 9 }, "data": [ { "type": "SmallVariant", "id": "902" }, { "type": "SmallVariant", "id": "903" }, { "type": "SmallVariant", "id": "1849" }, { "type": "SmallVariant", "id": "1923" }, { "type": "SmallVariant", "id": "1942" }, { "type": "SmallVariant", "id": "1952" }, { "type": "SmallVariant", "id": "2995" }, { "type": "SmallVariant", "id": "3007" }, { "type": "SmallVariant", "id": "3371" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/AXL/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/genes/AXL/variants/?format=api" } }, "genecombination_set": { "meta": { "count": 8 }, "data": [ { "type": "GeneCombination", "id": "281" }, { "type": "GeneCombination", "id": "282" }, { "type": "GeneCombination", "id": "614" }, { "type": "GeneCombination", "id": "649" }, { "type": "GeneCombination", "id": "665" }, { "type": "GeneCombination", "id": "1000" }, { "type": "GeneCombination", "id": "280" }, { "type": "GeneCombination", "id": "1130" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/AXL/relationships/genecombination_set?format=api", "related": "https://olida.ibsquare.be/api/genes/AXL/genecombinations/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genes/AXL/?format=api" } }, { "type": "Gene", "id": "CRY1", "attributes": { "go_molecular_function": [ "nuclear receptor binding", "protein kinase binding", "protein binding", "nucleotide binding", "kinase binding", "photoreceptor activity", "DNA binding" ], "pathway_id": [ "R-HSA-400253", "kegg_path:hsa04710", "kegg_path:hsa04710" ], "essential_gene": "Non-essential", "status": "CU", "uniprot_acc": "Q16526", "ensembl_id": "ENSG00000008405", "entrez_id": "1407", "chromosome_number": "12", "lastmodified": "2021-10-18T11:00:44.792132" }, "relationships": { "variant_set": { "meta": { "count": 1 }, "data": [ { "type": "SmallVariant", "id": "905" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/CRY1/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/genes/CRY1/variants/?format=api" } }, "genecombination_set": { "meta": { "count": 1 }, "data": [ { "type": "GeneCombination", "id": "282" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/CRY1/relationships/genecombination_set?format=api", "related": "https://olida.ibsquare.be/api/genes/CRY1/genecombinations/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genes/CRY1/?format=api" } }, { "type": "Gene", "id": "MASTL", "attributes": { "go_molecular_function": [ "protein serine/threonine kinase activity", "protein phosphatase 2A binding", "protein serine kinase activity", "ATP binding" ], "pathway_id": [ "R-HSA-1640170", "R-HSA-68875", "R-HSA-69278", "R-HSA-2465910", "R-HSA-68886" ], "essential_gene": null, "status": "CU", "uniprot_acc": "Q96GX5", "ensembl_id": "ENSG00000120539", "entrez_id": "84930", "chromosome_number": "10", "lastmodified": "2021-10-18T11:00:44.990727" }, "relationships": { "variant_set": { "meta": { "count": 1 }, "data": [ { "type": "SmallVariant", "id": "906" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/MASTL/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/genes/MASTL/variants/?format=api" } }, "genecombination_set": { "meta": { "count": 1 }, "data": [ { "type": "GeneCombination", "id": "282" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/MASTL/relationships/genecombination_set?format=api", "related": "https://olida.ibsquare.be/api/genes/MASTL/genecombinations/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genes/MASTL/?format=api" } } ], "meta": { "database_name": "OLIgogenic diseases DAtabase (OLIDA)", "resource_url": "olida.ibsquare.be", "api_release_year": "2021", "api_developer": [ [ "Arnau Dillen", "arnau.dillen@ulb.ac.be" ], [ "Charlotte Nachtegael", "charlotte.nachtegael@ulb.be" ] ], "api_version": "0.3", "api_maintainers": [ [ "Charlotte Nachtegael", "charlotte.nachtegael@ulb.be" ] ], "api_documentation": [ "olida.ibsquare.be/api/swagger", "olida.ibsquare.be/api/redoc" ], "copyright": "Copyright (c) 2025 · OLIDA All Rights Reserved.", "license": "CC Attribution-NonCommercial 4.0 International License", "ontologies": { "ORDO": "http://bioportal.bioontology.org/ontologies/ORDO", "GENO": "http://purl.obolibrary.org/obo/geno.owl", "MI": "http://purl.obolibrary.org/obo/mi.owl", "NCIT": "http://purl.obolibrary.org/obo/ncit.owl", "OGI": "http://purl.obolibrary.org/obo/ogi.owl", "OGG": "http://purl.obolibrary.org/obo/ogg.owl" }, "relevant_publications_doi": [ "10.1093/nar/gkv1068", "10.1093/database/baac023" ], "size": 3 } }