Gene List
This API endpoint handles listing (/genes) and retrieval (/genes/<ID>/) of genes that are contained in the database due to their association to
genetic variants that are involved in at least one oligogenic combination in OLIDA.
GET /api/genecombinations/254/genes/?format=api
{ "data": [ { "type": "Gene", "id": "DUSP6", "attributes": { "go_molecular_function": [ "['MAP kinase tyrosine/serine/threonine phosphatase activity', 'protein tyrosine phosphatase activity', 'phosphoprotein phosphatase activity', 'protein tyrosine/threonine phosphatase activity', 'protein binding', 'protein tyrosine/serine/threonine phosphatase activity', 'protein serine/threonine phosphatase activity']" ], "pathway_id": [ "kegg_path:hsa04010", "kegg_path:hsa05202", "kegg_path:hsa05221", "kegg_path:hsa04010", "kegg_path:hsa05202", "kegg_path:hsa05221", "R-HSA-112409", "R-HSA-1280215", "R-HSA-162582", "R-HSA-1643685", "R-HSA-166016", "R-HSA-166058", "R-HSA-166166", "R-HSA-166520", "R-HSA-168138", "R-HSA-168142", "R-HSA-168164", "R-HSA-168176", "R-HSA-168179", "R-HSA-168181", "R-HSA-168188", "R-HSA-168249", "R-HSA-168256", "R-HSA-168898", "R-HSA-181438", "R-HSA-187037", "R-HSA-198725", "R-HSA-198753", "R-HSA-202670", "R-HSA-448424", "R-HSA-449147", "R-HSA-450282", "R-HSA-450294", "R-HSA-5663202", "R-HSA-5673001", "R-HSA-5675221", "R-HSA-5683057", "R-HSA-5684996", "R-HSA-6802957", "R-HSA-9006934", "R-HSA-937061", "R-HSA-9652817", "R-HSA-975138", "R-HSA-975155", "R-HSA-975871" ], "essential_gene": "Essential", "status": "CU", "uniprot_acc": "Q16828", "ensembl_id": "None", "entrez_id": "ENSG00000139318", "chromosome_number": "12", "lastmodified": "2021-10-18T11:00:44.305694" }, "relationships": { "variant_set": { "meta": { "count": 6 }, "data": [ { "type": "SmallVariant", "id": "768" }, { "type": "SmallVariant", "id": "808" }, { "type": "SmallVariant", "id": "810" }, { "type": "SmallVariant", "id": "812" }, { "type": "SmallVariant", "id": "2581" }, { "type": "SmallVariant", "id": "3236" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/DUSP6/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/genes/DUSP6/variants/?format=api" } }, "genecombination_set": { "meta": { "count": 5 }, "data": [ { "type": "GeneCombination", "id": "241" }, { "type": "GeneCombination", "id": "253" }, { "type": "GeneCombination", "id": "254" }, { "type": "GeneCombination", "id": "859" }, { "type": "GeneCombination", "id": "1083" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/DUSP6/relationships/genecombination_set?format=api", "related": "https://olida.ibsquare.be/api/genes/DUSP6/genecombinations/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genes/DUSP6/?format=api" } }, { "type": "Gene", "id": "SPRY4", "attributes": { "go_molecular_function": [ "['protein kinase inhibitor activity', 'protein binding']" ], "pathway_id": [], "essential_gene": "Essential", "status": "CU", "uniprot_acc": "A0A0C4DFS6", "ensembl_id": "None", "entrez_id": "ENSG00000187678", "chromosome_number": "5", "lastmodified": "2021-10-18T11:00:44.751356" }, "relationships": { "variant_set": { "meta": { "count": 10 }, "data": [ { "type": "SmallVariant", "id": "784" }, { "type": "SmallVariant", "id": "811" }, { "type": "SmallVariant", "id": "1796" }, { "type": "SmallVariant", "id": "1829" }, { "type": "SmallVariant", "id": "2660" }, { "type": "SmallVariant", "id": "2692" }, { "type": "SmallVariant", "id": "2722" }, { "type": "SmallVariant", "id": "2728" }, { "type": "SmallVariant", "id": "3000" }, { "type": "SmallVariant", "id": "3270" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/SPRY4/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/genes/SPRY4/variants/?format=api" } }, "genecombination_set": { "meta": { "count": 11 }, "data": [ { "type": "GeneCombination", "id": "246" }, { "type": "GeneCombination", "id": "254" }, { "type": "GeneCombination", "id": "262" }, { "type": "GeneCombination", "id": "255" }, { "type": "GeneCombination", "id": "595" }, { "type": "GeneCombination", "id": "885" }, { "type": "GeneCombination", "id": "895" }, { "type": "GeneCombination", "id": "904" }, { "type": "GeneCombination", "id": "907" }, { "type": "GeneCombination", "id": "1002" }, { "type": "GeneCombination", "id": "1100" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/SPRY4/relationships/genecombination_set?format=api", "related": "https://olida.ibsquare.be/api/genes/SPRY4/genecombinations/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genes/SPRY4/?format=api" } } ], "meta": { "database_name": "OLIgogenic diseases DAtabase (OLIDA)", "resource_url": "olida.ibsquare.be", "api_release_year": "2021", "api_developer": [ [ "Arnau Dillen", "arnau.dillen@ulb.ac.be" ], [ "Charlotte Nachtegael", "charlotte.nachtegael@ulb.be" ] ], "api_version": "0.3", "api_maintainers": [ [ "Charlotte Nachtegael", "charlotte.nachtegael@ulb.be" ] ], "api_documentation": [ "olida.ibsquare.be/api/swagger", "olida.ibsquare.be/api/redoc" ], "copyright": "Copyright (c) 2025 · OLIDA All Rights Reserved.", "license": "CC Attribution-NonCommercial 4.0 International License", "ontologies": { "ORDO": "http://bioportal.bioontology.org/ontologies/ORDO", "GENO": "http://purl.obolibrary.org/obo/geno.owl", "MI": "http://purl.obolibrary.org/obo/mi.owl", "NCIT": "http://purl.obolibrary.org/obo/ncit.owl", "OGI": "http://purl.obolibrary.org/obo/ogi.owl", "OGG": "http://purl.obolibrary.org/obo/ogg.owl" }, "relevant_publications_doi": [ "10.1093/nar/gkv1068", "10.1093/database/baac023" ], "size": 2 } }