Gene Combination Instance – Django REST framework

This API endpoint handles listing (/references) and retrieval (/references/<ID>/) of References from the database
that support the inclusion of at least one oligogenic combination in OLIDA.

GET /api/genecombinations/235/?format=api

HTTP 200 OK
Allow: GET, HEAD, OPTIONS
Content-Type: application/vnd.api+json
Vary: Accept

{
    "data": {
        "type": "GeneCombination",
        "id": "235",
        "attributes": {
            "gene_relationship": [
                "Directly interacting",
                "Indirectly interacting",
                "Involved in the same disease",
                "Relevant pathways for phenotype",
                "Same pathway"
            ],
            "protein_interactions": [],
            "common_pathways": [
                "Signaling by NOTCH4",
                "Pre-NOTCH Expression and Processing",
                "Pre-NOTCH Transcription and Translation",
                "Gene expression (Transcription)",
                "Disease",
                "Developmental Biology",
                "Notch-HLH transcription pathway",
                "NOTCH2 intracellular domain regulates transcription",
                "Signaling by NOTCH2",
                "RNA Polymerase II Transcription",
                "Pathways in cancer",
                "Signaling by NOTCH",
                "Generic Transcription Pathway",
                "Signal Transduction",
                "NOTCH4 Intracellular Domain Regulates Transcription"
            ],
            "genecomb_metascore": 2,
            "lastmodified": "2021-10-18T11:00:57.252161"
        },
        "relationships": {
            "combination_set": {
                "meta": {
                    "count": 1
                },
                "data": [
                    {
                        "type": "Combination",
                        "id": "OLI347"
                    }
                ],
                "links": {
                    "self": "https://olida.ibsquare.be/api/genecombinations/235/relationships/combination_set?format=api",
                    "related": "https://olida.ibsquare.be/api/genecombinations/235/combinations/?format=api"
                }
            },
            "genes": {
                "meta": {
                    "count": 4
                },
                "data": [
                    {
                        "type": "Gene",
                        "id": "GLI2"
                    },
                    {
                        "type": "Gene",
                        "id": "MAMLD1"
                    },
                    {
                        "type": "Gene",
                        "id": "NOTCH2"
                    },
                    {
                        "type": "Gene",
                        "id": "RET"
                    }
                ],
                "links": {
                    "self": "https://olida.ibsquare.be/api/genecombinations/235/relationships/genes?format=api",
                    "related": "https://olida.ibsquare.be/api/genecombinations/235/genes/?format=api"
                }
            }
        },
        "links": {
            "self": "https://olida.ibsquare.be/api/genecombinations/235/?format=api"
        }
    }
}