Gene List
This API endpoint handles listing (/genes) and retrieval (/genes/<ID>/) of genes that are contained in the database due to their association to
genetic variants that are involved in at least one oligogenic combination in OLIDA.
GET /api/genecombinations/229/genes/?format=api
{ "data": [ { "type": "Gene", "id": "ANKRD11", "attributes": { "go_molecular_function": [], "pathway_id": [], "essential_gene": "Essential", "status": "CU", "uniprot_acc": "Q6UB99", "ensembl_id": "ENSG00000167522", "entrez_id": "29123", "chromosome_number": "16", "lastmodified": "2021-10-18T11:00:44.450313" }, "relationships": { "variant_set": { "meta": { "count": 1 }, "data": [ { "type": "SmallVariant", "id": "712" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/ANKRD11/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/genes/ANKRD11/variants/?format=api" } }, "genecombination_set": { "meta": { "count": 1 }, "data": [ { "type": "GeneCombination", "id": "229" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/ANKRD11/relationships/genecombination_set?format=api", "related": "https://olida.ibsquare.be/api/genes/ANKRD11/genecombinations/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genes/ANKRD11/?format=api" } }, { "type": "Gene", "id": "HOXD13", "attributes": { "go_molecular_function": [ "DNA-binding transcription activator activity, RNA polymerase II-specific", "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "sequence-specific double-stranded DNA binding", "DNA-binding transcription factor activity, RNA polymerase II-specific", "DNA-binding transcription factor activity", "DNA binding" ], "pathway_id": [], "essential_gene": "Essential", "status": "CU", "uniprot_acc": "P35453", "ensembl_id": "ENSG00000128714", "entrez_id": "3239", "chromosome_number": "2", "lastmodified": "2021-10-18T11:00:44.568667" }, "relationships": { "variant_set": { "meta": { "count": 1 }, "data": [ { "type": "SmallVariant", "id": "713" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/HOXD13/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/genes/HOXD13/variants/?format=api" } }, "genecombination_set": { "meta": { "count": 1 }, "data": [ { "type": "GeneCombination", "id": "229" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/HOXD13/relationships/genecombination_set?format=api", "related": "https://olida.ibsquare.be/api/genes/HOXD13/genecombinations/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genes/HOXD13/?format=api" } }, { "type": "Gene", "id": "MYO18B", "attributes": { "go_molecular_function": [ "ATP binding", "cytoskeletal motor activity", "actin binding", "nucleotide binding" ], "pathway_id": [], "essential_gene": "Essential", "status": "CU", "uniprot_acc": "Q8IUG5", "ensembl_id": "ENSG00000133454", "entrez_id": "84700", "chromosome_number": "22", "lastmodified": "2021-10-18T11:00:44.440172" }, "relationships": { "variant_set": { "meta": { "count": 5 }, "data": [ { "type": "SmallVariant", "id": "702" }, { "type": "SmallVariant", "id": "714" }, { "type": "SmallVariant", "id": "716" }, { "type": "SmallVariant", "id": "1734" }, { "type": "SmallVariant", "id": "1735" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/MYO18B/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/genes/MYO18B/variants/?format=api" } }, "genecombination_set": { "meta": { "count": 4 }, "data": [ { "type": "GeneCombination", "id": "225" }, { "type": "GeneCombination", "id": "229" }, { "type": "GeneCombination", "id": "230" }, { "type": "GeneCombination", "id": "571" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/MYO18B/relationships/genecombination_set?format=api", "related": "https://olida.ibsquare.be/api/genes/MYO18B/genecombinations/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genes/MYO18B/?format=api" } } ], "meta": { "database_name": "OLIgogenic diseases DAtabase (OLIDA)", "resource_url": "olida.ibsquare.be", "api_release_year": "2021", "api_developer": [ [ "Arnau Dillen", "arnau.dillen@ulb.ac.be" ], [ "Charlotte Nachtegael", "charlotte.nachtegael@ulb.be" ] ], "api_version": "0.3", "api_maintainers": [ [ "Charlotte Nachtegael", "charlotte.nachtegael@ulb.be" ] ], "api_documentation": [ "olida.ibsquare.be/api/swagger", "olida.ibsquare.be/api/redoc" ], "copyright": "Copyright (c) 2025 · OLIDA All Rights Reserved.", "license": "CC Attribution-NonCommercial 4.0 International License", "ontologies": { "ORDO": "http://bioportal.bioontology.org/ontologies/ORDO", "GENO": "http://purl.obolibrary.org/obo/geno.owl", "MI": "http://purl.obolibrary.org/obo/mi.owl", "NCIT": "http://purl.obolibrary.org/obo/ncit.owl", "OGI": "http://purl.obolibrary.org/obo/ogi.owl", "OGG": "http://purl.obolibrary.org/obo/ogg.owl" }, "relevant_publications_doi": [ "10.1093/nar/gkv1068", "10.1093/database/baac023" ], "size": 3 } }