Gene List
This API endpoint handles listing (/genes) and retrieval (/genes/<ID>/) of genes that are contained in the database due to their association to
genetic variants that are involved in at least one oligogenic combination in OLIDA.
GET /api/genecombinations/228/genes/?format=api
{ "data": [ { "type": "Gene", "id": "BAZ1B", "attributes": { "go_molecular_function": [ "protein binding", "transferase activity", "kinase activity", "ATP binding", "nucleotide binding", "histone binding", "protein tyrosine kinase activity", "non-membrane spanning protein tyrosine kinase activity", "metal ion binding" ], "pathway_id": [ "R-HSA-5250913", "R-HSA-212165", "R-HSA-5250924", "R-HSA-5250924", "R-HSA-212165", "R-HSA-5250913", "R-HSA-73894", "R-HSA-5693532", "R-HSA-5693565", "R-HSA-5693606", "R-HSA-74160", "R-HSA-5693565", "R-HSA-5693606", "R-HSA-5693532", "R-HSA-73894", "R-HSA-74160" ], "essential_gene": "Essential", "status": "CU", "uniprot_acc": "Q9UIG0", "ensembl_id": "ENSG00000009954", "entrez_id": "9031", "chromosome_number": "7", "lastmodified": "2021-10-18T11:00:44.401888" }, "relationships": { "variant_set": { "meta": { "count": 2 }, "data": [ { "type": "SmallVariant", "id": "698" }, { "type": "SmallVariant", "id": "710" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/BAZ1B/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/genes/BAZ1B/variants/?format=api" } }, "genecombination_set": { "meta": { "count": 2 }, "data": [ { "type": "GeneCombination", "id": "224" }, { "type": "GeneCombination", "id": "228" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/BAZ1B/relationships/genecombination_set?format=api", "related": "https://olida.ibsquare.be/api/genes/BAZ1B/genecombinations/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genes/BAZ1B/?format=api" } }, { "type": "Gene", "id": "COG1", "attributes": { "go_molecular_function": [ "protein binding" ], "pathway_id": [ "R-HSA-6807878", "R-HSA-948021", "R-HSA-446203", "R-HSA-5653656", "R-HSA-6811442", "R-HSA-6811438", "R-HSA-6811440", "R-HSA-199991", "R-HSA-199977", "R-HSA-597592", "R-HSA-392499" ], "essential_gene": null, "status": "CU", "uniprot_acc": "Q8WTW3", "ensembl_id": "ENSG00000166685", "entrez_id": "9382", "chromosome_number": "17", "lastmodified": "2021-10-18T11:00:44.979079" }, "relationships": { "variant_set": { "meta": { "count": 1 }, "data": [ { "type": "SmallVariant", "id": "711" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/COG1/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/genes/COG1/variants/?format=api" } }, "genecombination_set": { "meta": { "count": 1 }, "data": [ { "type": "GeneCombination", "id": "228" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/COG1/relationships/genecombination_set?format=api", "related": "https://olida.ibsquare.be/api/genes/COG1/genecombinations/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genes/COG1/?format=api" } } ], "meta": { "database_name": "OLIgogenic diseases DAtabase (OLIDA)", "resource_url": "olida.ibsquare.be", "api_release_year": "2021", "api_developer": [ [ "Arnau Dillen", "arnau.dillen@ulb.ac.be" ], [ "Charlotte Nachtegael", "charlotte.nachtegael@ulb.be" ] ], "api_version": "0.3", "api_maintainers": [ [ "Charlotte Nachtegael", "charlotte.nachtegael@ulb.be" ] ], "api_documentation": [ "olida.ibsquare.be/api/swagger", "olida.ibsquare.be/api/redoc" ], "copyright": "Copyright (c) 2025 · OLIDA All Rights Reserved.", "license": "CC Attribution-NonCommercial 4.0 International License", "ontologies": { "ORDO": "http://bioportal.bioontology.org/ontologies/ORDO", "GENO": "http://purl.obolibrary.org/obo/geno.owl", "MI": "http://purl.obolibrary.org/obo/mi.owl", "NCIT": "http://purl.obolibrary.org/obo/ncit.owl", "OGI": "http://purl.obolibrary.org/obo/ogi.owl", "OGG": "http://purl.obolibrary.org/obo/ogg.owl" }, "relevant_publications_doi": [ "10.1093/nar/gkv1068", "10.1093/database/baac023" ], "size": 2 } }