Gene List
This API endpoint handles listing (/genes) and retrieval (/genes/<ID>/) of genes that are contained in the database due to their association to
genetic variants that are involved in at least one oligogenic combination in OLIDA.
GET /api/genecombinations/211/genes/?format=api
{ "data": [ { "type": "Gene", "id": "CD2AP", "attributes": { "go_molecular_function": [ "SH3 domain binding", "structural constituent of cytoskeleton", "protein binding", "identical protein binding" ], "pathway_id": [ "R-HSA-1500931", "kegg_path:hsa05100", "R-HSA-373753" ], "essential_gene": "Non-essential", "status": "CU", "uniprot_acc": "Q9Y5K6", "ensembl_id": "ENSG00000198087", "entrez_id": "23607", "chromosome_number": "6", "lastmodified": "2021-10-18T11:00:44.765831" }, "relationships": { "variant_set": { "meta": { "count": 1 }, "data": [ { "type": "SmallVariant", "id": "621" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/CD2AP/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/genes/CD2AP/variants/?format=api" } }, "genecombination_set": { "meta": { "count": 1 }, "data": [ { "type": "GeneCombination", "id": "211" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/CD2AP/relationships/genecombination_set?format=api", "related": "https://olida.ibsquare.be/api/genes/CD2AP/genecombinations/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genes/CD2AP/?format=api" } }, { "type": "Gene", "id": "NPHS2", "attributes": { "go_molecular_function": [ "protein binding" ], "pathway_id": [ "R-HSA-373753", "R-HSA-1500931" ], "essential_gene": "Essential", "status": "CU", "uniprot_acc": "Q9NP85", "ensembl_id": "ENSG00000116218", "entrez_id": "7827", "chromosome_number": "1", "lastmodified": "2021-10-18T11:00:44.629281" }, "relationships": { "variant_set": { "meta": { "count": 5 }, "data": [ { "type": "SmallVariant", "id": "496" }, { "type": "SmallVariant", "id": "498" }, { "type": "SmallVariant", "id": "500" }, { "type": "SmallVariant", "id": "620" }, { "type": "SmallVariant", "id": "623" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/NPHS2/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/genes/NPHS2/variants/?format=api" } }, "genecombination_set": { "meta": { "count": 2 }, "data": [ { "type": "GeneCombination", "id": "166" }, { "type": "GeneCombination", "id": "211" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/NPHS2/relationships/genecombination_set?format=api", "related": "https://olida.ibsquare.be/api/genes/NPHS2/genecombinations/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genes/NPHS2/?format=api" } } ], "meta": { "database_name": "OLIgogenic diseases DAtabase (OLIDA)", "resource_url": "olida.ibsquare.be", "api_release_year": "2021", "api_developer": [ [ "Arnau Dillen", "arnau.dillen@ulb.ac.be" ], [ "Charlotte Nachtegael", "charlotte.nachtegael@ulb.be" ] ], "api_version": "0.3", "api_maintainers": [ [ "Charlotte Nachtegael", "charlotte.nachtegael@ulb.be" ] ], "api_documentation": [ "olida.ibsquare.be/api/swagger", "olida.ibsquare.be/api/redoc" ], "copyright": "Copyright (c) 2025 · OLIDA All Rights Reserved.", "license": "CC Attribution-NonCommercial 4.0 International License", "ontologies": { "ORDO": "http://bioportal.bioontology.org/ontologies/ORDO", "GENO": "http://purl.obolibrary.org/obo/geno.owl", "MI": "http://purl.obolibrary.org/obo/mi.owl", "NCIT": "http://purl.obolibrary.org/obo/ncit.owl", "OGI": "http://purl.obolibrary.org/obo/ogi.owl", "OGG": "http://purl.obolibrary.org/obo/ogg.owl" }, "relevant_publications_doi": [ "10.1093/nar/gkv1068", "10.1093/database/baac023" ], "size": 2 } }