Gene Combination Instance – Django REST framework

This API endpoint handles listing (/references) and retrieval (/references/<ID>/) of References from the database
that support the inclusion of at least one oligogenic combination in OLIDA.

GET /api/genecombinations/210/?format=api

HTTP 200 OK
Allow: GET, HEAD, OPTIONS
Content-Type: application/vnd.api+json
Vary: Accept

{
    "data": {
        "type": "GeneCombination",
        "id": "210",
        "attributes": {
            "gene_relationship": [
                "Involved in the same disease",
                "Same pathway"
            ],
            "protein_interactions": [],
            "common_pathways": [
                "Anchoring fibril formation",
                "Integrin cell surface interactions",
                "Non-integrin membrane-ECM interactions",
                "Axon guidance",
                "Focal adhesion",
                "Laminin interactions",
                "Assembly of collagen fibrils and other multimeric structures",
                "Signaling by Receptor Tyrosine Kinases",
                "Signaling by PDGF",
                "ECM-receptor interaction",
                "Extracellular matrix organization",
                "AGE-RAGE signaling pathway in diabetic complications",
                "Protein digestion and absorption",
                "Developmental Biology",
                "ECM proteoglycans",
                "Amoebiasis",
                "NCAM signaling for neurite out-growth",
                "Nervous system development",
                "Collagen degradation",
                "Collagen chain trimerization",
                "Degradation of the extracellular matrix",
                "Pathways in cancer",
                "Relaxin signaling pathway",
                "NCAM1 interactions",
                "Small cell lung cancer",
                "Crosslinking of collagen fibrils",
                "Collagen biosynthesis and modifying enzymes",
                "Collagen formation",
                "Human papillomavirus infection",
                "PI3K-Akt signaling pathway",
                "Signal Transduction"
            ],
            "genecomb_metascore": 2,
            "lastmodified": "2021-10-18T11:00:55.365076"
        },
        "relationships": {
            "combination_set": {
                "meta": {
                    "count": 1
                },
                "data": [
                    {
                        "type": "Combination",
                        "id": "OLI318"
                    }
                ],
                "links": {
                    "self": "https://olida.ibsquare.be/api/genecombinations/210/relationships/combination_set?format=api",
                    "related": "https://olida.ibsquare.be/api/genecombinations/210/combinations/?format=api"
                }
            },
            "genes": {
                "meta": {
                    "count": 3
                },
                "data": [
                    {
                        "type": "Gene",
                        "id": "COL4A3"
                    },
                    {
                        "type": "Gene",
                        "id": "COL4A4"
                    },
                    {
                        "type": "Gene",
                        "id": "COL4A6"
                    }
                ],
                "links": {
                    "self": "https://olida.ibsquare.be/api/genecombinations/210/relationships/genes?format=api",
                    "related": "https://olida.ibsquare.be/api/genecombinations/210/genes/?format=api"
                }
            }
        },
        "links": {
            "self": "https://olida.ibsquare.be/api/genecombinations/210/?format=api"
        }
    }
}