Gene List
This API endpoint handles listing (/genes) and retrieval (/genes/<ID>/) of genes that are contained in the database due to their association to
genetic variants that are involved in at least one oligogenic combination in OLIDA.
GET /api/genecombinations/207/genes/?format=api
{ "data": [ { "type": "Gene", "id": "NDP", "attributes": { "go_molecular_function": [ "cytokine activity", "protein binding", "frizzled binding" ], "pathway_id": [], "essential_gene": "Non-essential", "status": "CU", "uniprot_acc": "Q00604", "ensembl_id": "ENSG00000124479", "entrez_id": "4693", "chromosome_number": "X", "lastmodified": "2021-10-18T11:00:44.539319" }, "relationships": { "variant_set": { "meta": { "count": 2 }, "data": [ { "type": "SmallVariant", "id": "609" }, { "type": "SmallVariant", "id": "611" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/NDP/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/genes/NDP/variants/?format=api" } }, "genecombination_set": { "meta": { "count": 2 }, "data": [ { "type": "GeneCombination", "id": "207" }, { "type": "GeneCombination", "id": "208" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/NDP/relationships/genecombination_set?format=api", "related": "https://olida.ibsquare.be/api/genes/NDP/genecombinations/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genes/NDP/?format=api" } }, { "type": "Gene", "id": "ZNF408", "attributes": { "go_molecular_function": [ "['RNA polymerase II cis-regulatory region sequence-specific DNA binding', 'DNA-binding transcription factor activity, RNA polymerase II-specific', 'protein binding', 'metal ion binding', 'identical protein binding']" ], "pathway_id": [], "essential_gene": null, "status": "CU", "uniprot_acc": "Q9H9D4", "ensembl_id": "None", "entrez_id": "ENSG00000175213", "chromosome_number": "11", "lastmodified": "2021-10-18T11:00:44.465310" }, "relationships": { "variant_set": { "meta": { "count": 5 }, "data": [ { "type": "SmallVariant", "id": "605" }, { "type": "SmallVariant", "id": "608" }, { "type": "SmallVariant", "id": "610" }, { "type": "SmallVariant", "id": "2645" }, { "type": "SmallVariant", "id": "2646" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/ZNF408/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/genes/ZNF408/variants/?format=api" } }, "genecombination_set": { "meta": { "count": 5 }, "data": [ { "type": "GeneCombination", "id": "206" }, { "type": "GeneCombination", "id": "207" }, { "type": "GeneCombination", "id": "881" }, { "type": "GeneCombination", "id": "883" }, { "type": "GeneCombination", "id": "884" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/ZNF408/relationships/genecombination_set?format=api", "related": "https://olida.ibsquare.be/api/genes/ZNF408/genecombinations/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genes/ZNF408/?format=api" } } ], "meta": { "database_name": "OLIgogenic diseases DAtabase (OLIDA)", "resource_url": "olida.ibsquare.be", "api_release_year": "2021", "api_developer": [ [ "Arnau Dillen", "arnau.dillen@ulb.ac.be" ], [ "Charlotte Nachtegael", "charlotte.nachtegael@ulb.be" ] ], "api_version": "0.3", "api_maintainers": [ [ "Charlotte Nachtegael", "charlotte.nachtegael@ulb.be" ] ], "api_documentation": [ "olida.ibsquare.be/api/swagger", "olida.ibsquare.be/api/redoc" ], "copyright": "Copyright (c) 2025 · OLIDA All Rights Reserved.", "license": "CC Attribution-NonCommercial 4.0 International License", "ontologies": { "ORDO": "http://bioportal.bioontology.org/ontologies/ORDO", "GENO": "http://purl.obolibrary.org/obo/geno.owl", "MI": "http://purl.obolibrary.org/obo/mi.owl", "NCIT": "http://purl.obolibrary.org/obo/ncit.owl", "OGI": "http://purl.obolibrary.org/obo/ogi.owl", "OGG": "http://purl.obolibrary.org/obo/ogg.owl" }, "relevant_publications_doi": [ "10.1093/nar/gkv1068", "10.1093/database/baac023" ], "size": 2 } }