Gene List
This API endpoint handles listing (/genes) and retrieval (/genes/<ID>/) of genes that are contained in the database due to their association to
genetic variants that are involved in at least one oligogenic combination in OLIDA.
GET /api/genecombinations/203/genes/?format=api
{ "data": [ { "type": "Gene", "id": "OTUD4", "attributes": { "go_molecular_function": [ "['RNA binding', 'molecular adaptor activity', 'protein binding', 'Lys63-specific deubiquitinase activity', 'thiol-dependent deubiquitinase']" ], "pathway_id": [], "essential_gene": null, "status": "CU", "uniprot_acc": "Q01804", "ensembl_id": "None", "entrez_id": "ENSG00000164164", "chromosome_number": "4", "lastmodified": "2021-10-18T11:00:44.654507" }, "relationships": { "variant_set": { "meta": { "count": 5 }, "data": [ { "type": "SmallVariant", "id": "3009" }, { "type": "SmallVariant", "id": "587" }, { "type": "SmallVariant", "id": "2925" }, { "type": "SmallVariant", "id": "2975" }, { "type": "SmallVariant", "id": "3010" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/OTUD4/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/genes/OTUD4/variants/?format=api" } }, "genecombination_set": { "meta": { "count": 4 }, "data": [ { "type": "GeneCombination", "id": "203" }, { "type": "GeneCombination", "id": "971" }, { "type": "GeneCombination", "id": "991" }, { "type": "GeneCombination", "id": "1004" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/OTUD4/relationships/genecombination_set?format=api", "related": "https://olida.ibsquare.be/api/genes/OTUD4/genecombinations/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genes/OTUD4/?format=api" } }, { "type": "Gene", "id": "RNF216", "attributes": { "go_molecular_function": [ "['ubiquitin protein ligase activity', 'protein binding', 'metal ion binding']" ], "pathway_id": [ "R-HSA-168249", "R-HSA-168256", "R-HSA-168928", "R-HSA-936440" ], "essential_gene": null, "status": "CU", "uniprot_acc": "Q9NWF9", "ensembl_id": "None", "entrez_id": "ENSG00000011275", "chromosome_number": "7", "lastmodified": "2021-10-18T11:00:44.917313" }, "relationships": { "variant_set": { "meta": { "count": 9 }, "data": [ { "type": "SmallVariant", "id": "36" }, { "type": "SmallVariant", "id": "586" }, { "type": "SmallVariant", "id": "773" }, { "type": "SmallVariant", "id": "1799" }, { "type": "SmallVariant", "id": "2933" }, { "type": "SmallVariant", "id": "2978" }, { "type": "SmallVariant", "id": "3198" }, { "type": "SmallVariant", "id": "3238" }, { "type": "SmallVariant", "id": "3246" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/RNF216/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/genes/RNF216/variants/?format=api" } }, "genecombination_set": { "meta": { "count": 9 }, "data": [ { "type": "GeneCombination", "id": "14" }, { "type": "GeneCombination", "id": "203" }, { "type": "GeneCombination", "id": "242" }, { "type": "GeneCombination", "id": "596" }, { "type": "GeneCombination", "id": "974" }, { "type": "GeneCombination", "id": "993" }, { "type": "GeneCombination", "id": "1068" }, { "type": "GeneCombination", "id": "1085" }, { "type": "GeneCombination", "id": "1087" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/RNF216/relationships/genecombination_set?format=api", "related": "https://olida.ibsquare.be/api/genes/RNF216/genecombinations/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genes/RNF216/?format=api" } } ], "meta": { "database_name": "OLIgogenic diseases DAtabase (OLIDA)", "resource_url": "olida.ibsquare.be", "api_release_year": "2021", "api_developer": [ [ "Arnau Dillen", "arnau.dillen@ulb.ac.be" ], [ "Charlotte Nachtegael", "charlotte.nachtegael@ulb.be" ] ], "api_version": "0.3", "api_maintainers": [ [ "Charlotte Nachtegael", "charlotte.nachtegael@ulb.be" ] ], "api_documentation": [ "olida.ibsquare.be/api/swagger", "olida.ibsquare.be/api/redoc" ], "copyright": "Copyright (c) 2025 · OLIDA All Rights Reserved.", "license": "CC Attribution-NonCommercial 4.0 International License", "ontologies": { "ORDO": "http://bioportal.bioontology.org/ontologies/ORDO", "GENO": "http://purl.obolibrary.org/obo/geno.owl", "MI": "http://purl.obolibrary.org/obo/mi.owl", "NCIT": "http://purl.obolibrary.org/obo/ncit.owl", "OGI": "http://purl.obolibrary.org/obo/ogi.owl", "OGG": "http://purl.obolibrary.org/obo/ogg.owl" }, "relevant_publications_doi": [ "10.1093/nar/gkv1068", "10.1093/database/baac023" ], "size": 2 } }