Gene List
This API endpoint handles listing (/genes) and retrieval (/genes/<ID>/) of genes that are contained in the database due to their association to
genetic variants that are involved in at least one oligogenic combination in OLIDA.
GET /api/genecombinations/201/genes/?format=api
{ "data": [ { "type": "Gene", "id": "HSD3B2", "attributes": { "go_molecular_function": [ "cholesterol dehydrogenase activity", "catalytic activity", "isomerase activity", "3-beta-hydroxy-delta5-steroid dehydrogenase activity", "steroid delta-isomerase activity", "oxidoreductase activity" ], "pathway_id": [ "kegg_path:hsa01100", "kegg_path:hsa01100", "kegg_path:hsa04934", "kegg_path:hsa04934", "R-HSA-1430728", "R-HSA-196071", "kegg_path:hsa04927", "kegg_path:hsa04927", "R-HSA-8957322", "R-HSA-193048", "R-HSA-194002", "kegg_path:hsa04913", "kegg_path:hsa04913", "kegg_path:hsa04925", "kegg_path:hsa04925", "kegg_path:hsa00140", "kegg_path:hsa00140", "R-HSA-193993", "R-HSA-556833" ], "essential_gene": null, "status": "CU", "uniprot_acc": "P26439", "ensembl_id": "ENSG00000203859", "entrez_id": "3284", "chromosome_number": "1", "lastmodified": "2021-10-18T11:00:44.981233" }, "relationships": { "variant_set": { "meta": { "count": 2 }, "data": [ { "type": "SmallVariant", "id": "582" }, { "type": "SmallVariant", "id": "1290" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/HSD3B2/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/genes/HSD3B2/variants/?format=api" } }, "genecombination_set": { "meta": { "count": 2 }, "data": [ { "type": "GeneCombination", "id": "201" }, { "type": "GeneCombination", "id": "409" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/HSD3B2/relationships/genecombination_set?format=api", "related": "https://olida.ibsquare.be/api/genes/HSD3B2/genecombinations/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genes/HSD3B2/?format=api" } }, { "type": "Gene", "id": "SRD5A2", "attributes": { "go_molecular_function": [ "['amide binding', 'testosterone dehydrogenase [NAD(P)] activity', 'protein binding', 'oxidoreductase activity', 'cholestenone 5-alpha-reductase activity', '3-oxo-5-alpha-steroid 4-dehydrogenase activity', 'sterol 5-alpha reductase activity']" ], "pathway_id": [ "kegg_path:hsa00140", "kegg_path:hsa05215", "R-HSA-1430728", "R-HSA-193048", "R-HSA-196071", "R-HSA-556833", "R-HSA-8957322" ], "essential_gene": null, "status": "CU", "uniprot_acc": "None", "ensembl_id": "None", "entrez_id": "ENSG00000277893", "chromosome_number": "2", "lastmodified": "2021-10-18T11:00:44.477987" }, "relationships": { "variant_set": { "meta": { "count": 6 }, "data": [ { "type": "SmallVariant", "id": "583" }, { "type": "SmallVariant", "id": "2172" }, { "type": "SmallVariant", "id": "2179" }, { "type": "SmallVariant", "id": "3182" }, { "type": "SmallVariant", "id": "3206" }, { "type": "SmallVariant", "id": "3221" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/SRD5A2/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/genes/SRD5A2/variants/?format=api" } }, "genecombination_set": { "meta": { "count": 8 }, "data": [ { "type": "GeneCombination", "id": "201" }, { "type": "GeneCombination", "id": "268" }, { "type": "GeneCombination", "id": "739" }, { "type": "GeneCombination", "id": "1077" }, { "type": "GeneCombination", "id": "1063" }, { "type": "GeneCombination", "id": "1071" }, { "type": "GeneCombination", "id": "1084" }, { "type": "GeneCombination", "id": "1090" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/SRD5A2/relationships/genecombination_set?format=api", "related": "https://olida.ibsquare.be/api/genes/SRD5A2/genecombinations/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genes/SRD5A2/?format=api" } } ], "meta": { "database_name": "OLIgogenic diseases DAtabase (OLIDA)", "resource_url": "olida.ibsquare.be", "api_release_year": "2021", "api_developer": [ [ "Arnau Dillen", "arnau.dillen@ulb.ac.be" ], [ "Charlotte Nachtegael", "charlotte.nachtegael@ulb.be" ] ], "api_version": "0.3", "api_maintainers": [ [ "Charlotte Nachtegael", "charlotte.nachtegael@ulb.be" ] ], "api_documentation": [ "olida.ibsquare.be/api/swagger", "olida.ibsquare.be/api/redoc" ], "copyright": "Copyright (c) 2025 · OLIDA All Rights Reserved.", "license": "CC Attribution-NonCommercial 4.0 International License", "ontologies": { "ORDO": "http://bioportal.bioontology.org/ontologies/ORDO", "GENO": "http://purl.obolibrary.org/obo/geno.owl", "MI": "http://purl.obolibrary.org/obo/mi.owl", "NCIT": "http://purl.obolibrary.org/obo/ncit.owl", "OGI": "http://purl.obolibrary.org/obo/ogi.owl", "OGG": "http://purl.obolibrary.org/obo/ogg.owl" }, "relevant_publications_doi": [ "10.1093/nar/gkv1068", "10.1093/database/baac023" ], "size": 2 } }