Gene List
This API endpoint handles listing (/genes) and retrieval (/genes/<ID>/) of genes that are contained in the database due to their association to
genetic variants that are involved in at least one oligogenic combination in OLIDA.
GET /api/genecombinations/167/genes/?format=api
{ "data": [ { "type": "Gene", "id": "HERC2", "attributes": { "go_molecular_function": [ "ubiquitin-protein transferase activity", "ubiquitin protein ligase activity", "transferase activity", "guanyl-nucleotide exchange factor activity", "zinc ion binding", "metal ion binding" ], "pathway_id": [ "R-HSA-983168", "R-HSA-5693606", "R-HSA-597592", "R-HSA-73894", "R-HSA-1280218", "R-HSA-5693571", "R-HSA-5693607", "R-HSA-983169", "R-HSA-1640170", "R-HSA-3108232", "R-HSA-5693538", "R-HSA-69481", "kegg_path:hsa04120", "kegg_path:hsa04120", "R-HSA-1280218", "R-HSA-3108214", "R-HSA-392499", "R-HSA-5693571", "R-HSA-5693532", "R-HSA-5693565", "R-HSA-983168", "R-HSA-168256", "R-HSA-69473", "R-HSA-73894", "R-HSA-5693606", "R-HSA-597592", "R-HSA-5693538", "R-HSA-1640170", "R-HSA-2990846", "R-HSA-3108232", "R-HSA-69481", "R-HSA-69620", "R-HSA-5693607", "R-HSA-5693567", "R-HSA-983169", "R-HSA-168256", "R-HSA-69473", "kegg_path:hsa04120", "kegg_path:hsa04120", "R-HSA-3108214", "R-HSA-392499", "R-HSA-5693532", "R-HSA-5693565", "R-HSA-69620", "R-HSA-5693567", "R-HSA-2990846" ], "essential_gene": "Essential", "status": "CU", "uniprot_acc": "O95714", "ensembl_id": "ENSG00000128731", "entrez_id": "8924", "chromosome_number": "15", "lastmodified": "2021-10-18T11:00:44.433361" }, "relationships": { "variant_set": { "meta": { "count": 1 }, "data": [ { "type": "SmallVariant", "id": "502" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/HERC2/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/genes/HERC2/variants/?format=api" } }, "genecombination_set": { "meta": { "count": 1 }, "data": [ { "type": "GeneCombination", "id": "167" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/HERC2/relationships/genecombination_set?format=api", "related": "https://olida.ibsquare.be/api/genes/HERC2/genecombinations/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genes/HERC2/?format=api" } }, { "type": "Gene", "id": "NOTCH2", "attributes": { "go_molecular_function": [ "calcium ion binding", "protein binding", "enzyme binding", "NF-kappaB binding", "signaling receptor activity" ], "pathway_id": [ "R-HSA-1912399", "R-HSA-1912408", "R-HSA-162582", "kegg_path:hsa04330", "kegg_path:hsa04919", "kegg_path:hsa05200", "kegg_path:hsa05206", "R-HSA-350054", "R-HSA-74160", "R-HSA-1980145", "kegg_path:hsa05224", "kegg_path:hsa01522", "R-HSA-9013695", "R-HSA-212436", "R-HSA-9013694", "kegg_path:hsa05165", "R-HSA-3906995", "kegg_path:hsa04658", "R-HSA-2197563", "R-HSA-5668914", "kegg_path:hsa04919", "kegg_path:hsa04330", "R-HSA-3781865", "kegg_path:hsa05206", "R-HSA-1643685", "kegg_path:hsa05200", "R-HSA-2979096", "kegg_path:hsa05224", "R-HSA-1912422", "kegg_path:hsa01522", "kegg_path:hsa05165", "R-HSA-157118", "R-HSA-1912420", "R-HSA-5083630", "R-HSA-73857", "kegg_path:hsa04658" ], "essential_gene": "Essential", "status": "CU", "uniprot_acc": "Q04721", "ensembl_id": "ENSG00000134250", "entrez_id": "4853", "chromosome_number": "1", "lastmodified": "2021-10-18T11:00:44.464507" }, "relationships": { "variant_set": { "meta": { "count": 6 }, "data": [ { "type": "SmallVariant", "id": "501" }, { "type": "SmallVariant", "id": "724" }, { "type": "SmallVariant", "id": "762" }, { "type": "SmallVariant", "id": "1293" }, { "type": "SmallVariant", "id": "1313" }, { "type": "SmallVariant", "id": "2305" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/NOTCH2/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/genes/NOTCH2/variants/?format=api" } }, "genecombination_set": { "meta": { "count": 7 }, "data": [ { "type": "GeneCombination", "id": "240" }, { "type": "GeneCombination", "id": "167" }, { "type": "GeneCombination", "id": "232" }, { "type": "GeneCombination", "id": "235" }, { "type": "GeneCombination", "id": "409" }, { "type": "GeneCombination", "id": "411" }, { "type": "GeneCombination", "id": "774" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/NOTCH2/relationships/genecombination_set?format=api", "related": "https://olida.ibsquare.be/api/genes/NOTCH2/genecombinations/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genes/NOTCH2/?format=api" } } ], "meta": { "database_name": "OLIgogenic diseases DAtabase (OLIDA)", "resource_url": "olida.ibsquare.be", "api_release_year": "2021", "api_developer": [ [ "Arnau Dillen", "arnau.dillen@ulb.ac.be" ], [ "Charlotte Nachtegael", "charlotte.nachtegael@ulb.be" ] ], "api_version": "0.3", "api_maintainers": [ [ "Charlotte Nachtegael", "charlotte.nachtegael@ulb.be" ] ], "api_documentation": [ "olida.ibsquare.be/api/swagger", "olida.ibsquare.be/api/redoc" ], "copyright": "Copyright (c) 2026 · OLIDA All Rights Reserved.", "license": "CC Attribution-NonCommercial 4.0 International License", "ontologies": { "ORDO": "http://bioportal.bioontology.org/ontologies/ORDO", "GENO": "http://purl.obolibrary.org/obo/geno.owl", "MI": "http://purl.obolibrary.org/obo/mi.owl", "NCIT": "http://purl.obolibrary.org/obo/ncit.owl", "OGI": "http://purl.obolibrary.org/obo/ogi.owl", "OGG": "http://purl.obolibrary.org/obo/ogg.owl" }, "relevant_publications_doi": [ "10.1093/nar/gkv1068", "10.1093/database/baac023" ], "size": 2 } }