Gene List
This API endpoint handles listing (/genes) and retrieval (/genes/<ID>/) of genes that are contained in the database due to their association to
genetic variants that are involved in at least one oligogenic combination in OLIDA.
GET /api/genecombinations/162/genes/?format=api
{ "data": [ { "type": "Gene", "id": "DPT", "attributes": { "go_molecular_function": [ "extracellular matrix structural constituent", "protein binding" ], "pathway_id": [], "essential_gene": "Non-essential", "status": "CU", "uniprot_acc": "Q07507", "ensembl_id": "ENSG00000143196", "entrez_id": "1805", "chromosome_number": "1", "lastmodified": "2021-10-18T11:00:44.285688" }, "relationships": { "variant_set": { "meta": { "count": 1 }, "data": [ { "type": "SmallVariant", "id": "485" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/DPT/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/genes/DPT/variants/?format=api" } }, "genecombination_set": { "meta": { "count": 2 }, "data": [ { "type": "GeneCombination", "id": "162" }, { "type": "GeneCombination", "id": "163" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/DPT/relationships/genecombination_set?format=api", "related": "https://olida.ibsquare.be/api/genes/DPT/genecombinations/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genes/DPT/?format=api" } }, { "type": "Gene", "id": "FOXC1", "attributes": { "go_molecular_function": [ "protein binding", "DNA-binding transcription factor activity", "DNA binding", "DNA binding, bending" ], "pathway_id": [], "essential_gene": "Essential", "status": "CU", "uniprot_acc": "Q12948", "ensembl_id": "ENSG00000054598", "entrez_id": "2296", "chromosome_number": "6", "lastmodified": "2021-10-18T11:00:44.325333" }, "relationships": { "variant_set": { "meta": { "count": 2 }, "data": [ { "type": "SmallVariant", "id": "484" }, { "type": "SmallVariant", "id": "491" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/FOXC1/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/genes/FOXC1/variants/?format=api" } }, "genecombination_set": { "meta": { "count": 3 }, "data": [ { "type": "GeneCombination", "id": "162" }, { "type": "GeneCombination", "id": "163" }, { "type": "GeneCombination", "id": "165" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/FOXC1/relationships/genecombination_set?format=api", "related": "https://olida.ibsquare.be/api/genes/FOXC1/genecombinations/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genes/FOXC1/?format=api" } }, { "type": "Gene", "id": "NFATC1", "attributes": { "go_molecular_function": [ "protein binding", "DNA-binding transcription factor activity", "DNA binding", "FK506 binding" ], "pathway_id": [ "kegg_path:hsa05161", "kegg_path:hsa04625", "kegg_path:hsa04660", "kegg_path:hsa05235", "kegg_path:hsa05135", "kegg_path:hsa04933", "kegg_path:hsa05167", "R-HSA-5607763", "kegg_path:hsa04662", "kegg_path:hsa05170", "kegg_path:hsa04380", "R-HSA-1168372", "R-HSA-168256", "kegg_path:hsa04659", "R-HSA-5607764", "R-HSA-1280218", "R-HSA-168249", "R-HSA-5621481", "R-HSA-2871809", "R-HSA-4086398", "kegg_path:hsa04022", "kegg_path:hsa04218", "R-HSA-3858494", "kegg_path:hsa04921", "kegg_path:hsa05166", "kegg_path:hsa05163", "kegg_path:hsa04658", "kegg_path:hsa04650", "R-HSA-162582", "R-HSA-2025928", "kegg_path:hsa04310", "R-HSA-195721", "R-HSA-2454202", "kegg_path:hsa04010", "kegg_path:hsa05321", "R-HSA-983705", "kegg_path:hsa04024" ], "essential_gene": "Essential", "status": "CU", "uniprot_acc": "O95644", "ensembl_id": "ENSG00000131196", "entrez_id": "4772", "chromosome_number": "18", "lastmodified": "2021-10-18T11:00:44.226046" }, "relationships": { "variant_set": { "meta": { "count": 1 }, "data": [ { "type": "SmallVariant", "id": "486" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/NFATC1/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/genes/NFATC1/variants/?format=api" } }, "genecombination_set": { "meta": { "count": 1 }, "data": [ { "type": "GeneCombination", "id": "162" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/NFATC1/relationships/genecombination_set?format=api", "related": "https://olida.ibsquare.be/api/genes/NFATC1/genecombinations/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genes/NFATC1/?format=api" } } ], "meta": { "database_name": "OLIgogenic diseases DAtabase (OLIDA)", "resource_url": "olida.ibsquare.be", "api_release_year": "2021", "api_developer": [ [ "Arnau Dillen", "arnau.dillen@ulb.ac.be" ], [ "Charlotte Nachtegael", "charlotte.nachtegael@ulb.be" ] ], "api_version": "0.3", "api_maintainers": [ [ "Charlotte Nachtegael", "charlotte.nachtegael@ulb.be" ] ], "api_documentation": [ "olida.ibsquare.be/api/swagger", "olida.ibsquare.be/api/redoc" ], "copyright": "Copyright (c) 2025 · OLIDA All Rights Reserved.", "license": "CC Attribution-NonCommercial 4.0 International License", "ontologies": { "ORDO": "http://bioportal.bioontology.org/ontologies/ORDO", "GENO": "http://purl.obolibrary.org/obo/geno.owl", "MI": "http://purl.obolibrary.org/obo/mi.owl", "NCIT": "http://purl.obolibrary.org/obo/ncit.owl", "OGI": "http://purl.obolibrary.org/obo/ogi.owl", "OGG": "http://purl.obolibrary.org/obo/ogg.owl" }, "relevant_publications_doi": [ "10.1093/nar/gkv1068", "10.1093/database/baac023" ], "size": 3 } }