Gene List
This API endpoint handles listing (/genes) and retrieval (/genes/<ID>/) of genes that are contained in the database due to their association to
genetic variants that are involved in at least one oligogenic combination in OLIDA.
GET /api/genecombinations/144/genes/?format=api
{ "data": [ { "type": "Gene", "id": "IFNAR1", "attributes": { "go_molecular_function": [ "cytokine receptor activity", "type I interferon receptor activity", "type I interferon binding", "protein binding" ], "pathway_id": [ "kegg_path:hsa05200", "kegg_path:hsa05171", "kegg_path:hsa04650", "kegg_path:hsa04621", "kegg_path:hsa04630", "kegg_path:hsa05160", "R-HSA-913531", "kegg_path:hsa05165", "kegg_path:hsa05167", "kegg_path:hsa05168", "R-HSA-912694", "kegg_path:hsa05162", "R-HSA-909733", "kegg_path:hsa05161", "kegg_path:hsa04620", "R-HSA-5663205", "kegg_path:hsa04151", "kegg_path:hsa05169", "R-HSA-1643685", "R-HSA-9679506", "kegg_path:hsa04380", "R-HSA-9679191", "kegg_path:hsa04217", "R-HSA-168256", "kegg_path:hsa04060", "kegg_path:hsa05164", "R-HSA-1280215" ], "essential_gene": "Non-essential", "status": "CU", "uniprot_acc": "P17181", "ensembl_id": "ENSG00000142166", "entrez_id": "3454", "chromosome_number": "21", "lastmodified": "2021-10-18T11:00:44.813578" }, "relationships": { "variant_set": { "meta": { "count": 1 }, "data": [ { "type": "SmallVariant", "id": "427" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/IFNAR1/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/genes/IFNAR1/variants/?format=api" } }, "genecombination_set": { "meta": { "count": 1 }, "data": [ { "type": "GeneCombination", "id": "144" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/IFNAR1/relationships/genecombination_set?format=api", "related": "https://olida.ibsquare.be/api/genes/IFNAR1/genecombinations/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genes/IFNAR1/?format=api" } }, { "type": "Gene", "id": "IFNGR2", "attributes": { "go_molecular_function": [ "protein binding", "interferon-gamma receptor activity" ], "pathway_id": [ "kegg_path:hsa04658", "kegg_path:hsa05168", "kegg_path:hsa05235", "kegg_path:hsa04066", "kegg_path:hsa05142", "kegg_path:hsa05321", "kegg_path:hsa05235", "kegg_path:hsa04658", "kegg_path:hsa05168", "kegg_path:hsa04066", "kegg_path:hsa05321", "kegg_path:hsa05142", "R-HSA-877300", "R-HSA-5663205", "R-HSA-9679506", "kegg_path:hsa05200", "kegg_path:hsa04217", "R-HSA-168256", "kegg_path:hsa04060", "kegg_path:hsa04659", "kegg_path:hsa05152", "kegg_path:hsa05145", "kegg_path:hsa05200", "kegg_path:hsa04380", "kegg_path:hsa04630", "kegg_path:hsa04060", "kegg_path:hsa04217", "kegg_path:hsa05200", "kegg_path:hsa04630", "kegg_path:hsa04380", "kegg_path:hsa04060", "kegg_path:hsa04217", "kegg_path:hsa04659", "kegg_path:hsa05152", "kegg_path:hsa05145", "kegg_path:hsa04380", "kegg_path:hsa04630", "kegg_path:hsa05200", "R-HSA-9679191", "kegg_path:hsa04217", "R-HSA-168256", "kegg_path:hsa04060", "R-HSA-877300", "kegg_path:hsa04659", "kegg_path:hsa05145", "kegg_path:hsa05152", "R-HSA-9679506", "R-HSA-5663205", "kegg_path:hsa04650", "kegg_path:hsa04066", "R-HSA-1643685", "kegg_path:hsa05321", "kegg_path:hsa05142", "R-HSA-913531", "kegg_path:hsa05140", "R-HSA-877312", "kegg_path:hsa05235", "kegg_path:hsa04658", "kegg_path:hsa05168", "kegg_path:hsa05164", "kegg_path:hsa04066", "kegg_path:hsa04650", "R-HSA-1280215", "kegg_path:hsa05142", "kegg_path:hsa05321", "kegg_path:hsa05140", "kegg_path:hsa05164", "kegg_path:hsa04658", "kegg_path:hsa05168", "kegg_path:hsa05235", "kegg_path:hsa05140", "kegg_path:hsa05164", "R-HSA-1280215", "kegg_path:hsa04650", "R-HSA-913531", "kegg_path:hsa05140", "R-HSA-877312", "kegg_path:hsa05164", "kegg_path:hsa04650", "R-HSA-1643685", "kegg_path:hsa04659", "kegg_path:hsa05145", "kegg_path:hsa05152", "kegg_path:hsa04630", "kegg_path:hsa04380", "R-HSA-9679191" ], "essential_gene": "Non-essential", "status": "CU", "uniprot_acc": "P38484", "ensembl_id": "ENSG00000159128", "entrez_id": "3460", "chromosome_number": "21", "lastmodified": "2021-10-18T11:00:44.398441" }, "relationships": { "variant_set": { "meta": { "count": 1 }, "data": [ { "type": "SmallVariant", "id": "426" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/IFNGR2/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/genes/IFNGR2/variants/?format=api" } }, "genecombination_set": { "meta": { "count": 1 }, "data": [ { "type": "GeneCombination", "id": "144" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/IFNGR2/relationships/genecombination_set?format=api", "related": "https://olida.ibsquare.be/api/genes/IFNGR2/genecombinations/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genes/IFNGR2/?format=api" } } ], "meta": { "database_name": "OLIgogenic diseases DAtabase (OLIDA)", "resource_url": "olida.ibsquare.be", "api_release_year": "2021", "api_developer": [ [ "Arnau Dillen", "arnau.dillen@ulb.ac.be" ], [ "Charlotte Nachtegael", "charlotte.nachtegael@ulb.be" ] ], "api_version": "0.3", "api_maintainers": [ [ "Charlotte Nachtegael", "charlotte.nachtegael@ulb.be" ] ], "api_documentation": [ "olida.ibsquare.be/api/swagger", "olida.ibsquare.be/api/redoc" ], "copyright": "Copyright (c) 2025 · OLIDA All Rights Reserved.", "license": "CC Attribution-NonCommercial 4.0 International License", "ontologies": { "ORDO": "http://bioportal.bioontology.org/ontologies/ORDO", "GENO": "http://purl.obolibrary.org/obo/geno.owl", "MI": "http://purl.obolibrary.org/obo/mi.owl", "NCIT": "http://purl.obolibrary.org/obo/ncit.owl", "OGI": "http://purl.obolibrary.org/obo/ogi.owl", "OGG": "http://purl.obolibrary.org/obo/ogg.owl" }, "relevant_publications_doi": [ "10.1093/nar/gkv1068", "10.1093/database/baac023" ], "size": 2 } }