Gene List
This API endpoint handles listing (/genes) and retrieval (/genes/<ID>/) of genes that are contained in the database due to their association to
genetic variants that are involved in at least one oligogenic combination in OLIDA.
GET /api/genecombinations/141/genes/?format=api
{ "data": [ { "type": "Gene", "id": "CC2D2A", "attributes": { "go_molecular_function": [], "pathway_id": [ "R-HSA-5620912", "R-HSA-1852241", "R-HSA-5617833" ], "essential_gene": "Non-essential", "status": "CU", "uniprot_acc": "Q9P2K1", "ensembl_id": "ENSG00000048342", "entrez_id": "57545", "chromosome_number": "4", "lastmodified": "2021-10-18T11:00:44.589776" }, "relationships": { "variant_set": { "meta": { "count": 5 }, "data": [ { "type": "SmallVariant", "id": "789" }, { "type": "SmallVariant", "id": "418" }, { "type": "SmallVariant", "id": "420" }, { "type": "SmallVariant", "id": "481" }, { "type": "SmallVariant", "id": "483" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/CC2D2A/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/genes/CC2D2A/variants/?format=api" } }, "genecombination_set": { "meta": { "count": 4 }, "data": [ { "type": "GeneCombination", "id": "141" }, { "type": "GeneCombination", "id": "142" }, { "type": "GeneCombination", "id": "161" }, { "type": "GeneCombination", "id": "247" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/CC2D2A/relationships/genecombination_set?format=api", "related": "https://olida.ibsquare.be/api/genes/CC2D2A/genecombinations/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genes/CC2D2A/?format=api" } }, { "type": "Gene", "id": "NPHP3", "attributes": { "go_molecular_function": [ "['protein binding']" ], "pathway_id": [ "R-HSA-1852241", "R-HSA-5617833", "R-HSA-5620920", "R-HSA-5624138" ], "essential_gene": "Essential", "status": "CU", "uniprot_acc": "Q7Z494", "ensembl_id": "None", "entrez_id": "ENSG00000113971", "chromosome_number": "3", "lastmodified": "2021-10-18T11:00:44.790969" }, "relationships": { "variant_set": { "meta": { "count": 9 }, "data": [ { "type": "SmallVariant", "id": "414" }, { "type": "SmallVariant", "id": "409" }, { "type": "SmallVariant", "id": "410" }, { "type": "SmallVariant", "id": "413" }, { "type": "SmallVariant", "id": "417" }, { "type": "SmallVariant", "id": "419" }, { "type": "SmallVariant", "id": "786" }, { "type": "SmallVariant", "id": "787" }, { "type": "SmallVariant", "id": "3480" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/NPHP3/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/genes/NPHP3/variants/?format=api" } }, "genecombination_set": { "meta": { "count": 6 }, "data": [ { "type": "GeneCombination", "id": "138" }, { "type": "GeneCombination", "id": "139" }, { "type": "GeneCombination", "id": "140" }, { "type": "GeneCombination", "id": "141" }, { "type": "GeneCombination", "id": "247" }, { "type": "GeneCombination", "id": "1170" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/NPHP3/relationships/genecombination_set?format=api", "related": "https://olida.ibsquare.be/api/genes/NPHP3/genecombinations/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genes/NPHP3/?format=api" } } ], "meta": { "database_name": "OLIgogenic diseases DAtabase (OLIDA)", "resource_url": "olida.ibsquare.be", "api_release_year": "2021", "api_developer": [ [ "Arnau Dillen", "arnau.dillen@ulb.ac.be" ], [ "Charlotte Nachtegael", "charlotte.nachtegael@ulb.be" ] ], "api_version": "0.3", "api_maintainers": [ [ "Charlotte Nachtegael", "charlotte.nachtegael@ulb.be" ] ], "api_documentation": [ "olida.ibsquare.be/api/swagger", "olida.ibsquare.be/api/redoc" ], "copyright": "Copyright (c) 2025 · OLIDA All Rights Reserved.", "license": "CC Attribution-NonCommercial 4.0 International License", "ontologies": { "ORDO": "http://bioportal.bioontology.org/ontologies/ORDO", "GENO": "http://purl.obolibrary.org/obo/geno.owl", "MI": "http://purl.obolibrary.org/obo/mi.owl", "NCIT": "http://purl.obolibrary.org/obo/ncit.owl", "OGI": "http://purl.obolibrary.org/obo/ogi.owl", "OGG": "http://purl.obolibrary.org/obo/ogg.owl" }, "relevant_publications_doi": [ "10.1093/nar/gkv1068", "10.1093/database/baac023" ], "size": 2 } }