Gene List
This API endpoint handles listing (/genes) and retrieval (/genes/<ID>/) of genes that are contained in the database due to their association to
genetic variants that are involved in at least one oligogenic combination in OLIDA.
GET /api/genecombinations/14/genes/?format=api
{ "data": [ { "type": "Gene", "id": "RNF216", "attributes": { "go_molecular_function": [ "['ubiquitin protein ligase activity', 'protein binding', 'metal ion binding']" ], "pathway_id": [ "R-HSA-168249", "R-HSA-168256", "R-HSA-168928", "R-HSA-936440" ], "essential_gene": null, "status": "CU", "uniprot_acc": "Q9NWF9", "ensembl_id": "None", "entrez_id": "ENSG00000011275", "chromosome_number": "7", "lastmodified": "2021-10-18T11:00:44.917313" }, "relationships": { "variant_set": { "meta": { "count": 9 }, "data": [ { "type": "SmallVariant", "id": "36" }, { "type": "SmallVariant", "id": "586" }, { "type": "SmallVariant", "id": "773" }, { "type": "SmallVariant", "id": "1799" }, { "type": "SmallVariant", "id": "2933" }, { "type": "SmallVariant", "id": "2978" }, { "type": "SmallVariant", "id": "3198" }, { "type": "SmallVariant", "id": "3238" }, { "type": "SmallVariant", "id": "3246" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/RNF216/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/genes/RNF216/variants/?format=api" } }, "genecombination_set": { "meta": { "count": 9 }, "data": [ { "type": "GeneCombination", "id": "14" }, { "type": "GeneCombination", "id": "203" }, { "type": "GeneCombination", "id": "242" }, { "type": "GeneCombination", "id": "596" }, { "type": "GeneCombination", "id": "974" }, { "type": "GeneCombination", "id": "993" }, { "type": "GeneCombination", "id": "1068" }, { "type": "GeneCombination", "id": "1085" }, { "type": "GeneCombination", "id": "1087" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/RNF216/relationships/genecombination_set?format=api", "related": "https://olida.ibsquare.be/api/genes/RNF216/genecombinations/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genes/RNF216/?format=api" } }, { "type": "Gene", "id": "SRA1", "attributes": { "go_molecular_function": [ "['steroid receptor RNA activator RNA binding', 'nuclear receptor coactivator activity', 'transcription coactivator activity', 'DNA binding', 'protein binding']" ], "pathway_id": [], "essential_gene": null, "status": "CU", "uniprot_acc": "Q9HD15", "ensembl_id": "None", "entrez_id": "ENSG00000213523", "chromosome_number": "5", "lastmodified": "2021-10-18T11:00:44.268998" }, "relationships": { "variant_set": { "meta": { "count": 7 }, "data": [ { "type": "SmallVariant", "id": "35" }, { "type": "SmallVariant", "id": "1211" }, { "type": "SmallVariant", "id": "1424" }, { "type": "SmallVariant", "id": "2777" }, { "type": "SmallVariant", "id": "3299" }, { "type": "SmallVariant", "id": "3301" }, { "type": "SmallVariant", "id": "3305" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/SRA1/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/genes/SRA1/variants/?format=api" } }, "genecombination_set": { "meta": { "count": 8 }, "data": [ { "type": "GeneCombination", "id": "14" }, { "type": "GeneCombination", "id": "386" }, { "type": "GeneCombination", "id": "448" }, { "type": "GeneCombination", "id": "928" }, { "type": "GeneCombination", "id": "1109" }, { "type": "GeneCombination", "id": "1110" }, { "type": "GeneCombination", "id": "1112" }, { "type": "GeneCombination", "id": "1124" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/SRA1/relationships/genecombination_set?format=api", "related": "https://olida.ibsquare.be/api/genes/SRA1/genecombinations/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genes/SRA1/?format=api" } } ], "meta": { "database_name": "OLIgogenic diseases DAtabase (OLIDA)", "resource_url": "olida.ibsquare.be", "api_release_year": "2021", "api_developer": [ [ "Arnau Dillen", "arnau.dillen@ulb.ac.be" ], [ "Charlotte Nachtegael", "charlotte.nachtegael@ulb.be" ] ], "api_version": "0.3", "api_maintainers": [ [ "Charlotte Nachtegael", "charlotte.nachtegael@ulb.be" ] ], "api_documentation": [ "olida.ibsquare.be/api/swagger", "olida.ibsquare.be/api/redoc" ], "copyright": "Copyright (c) 2024 · OLIDA All Rights Reserved.", "license": "CC Attribution-NonCommercial 4.0 International License", "ontologies": { "ORDO": "http://bioportal.bioontology.org/ontologies/ORDO", "GENO": "http://purl.obolibrary.org/obo/geno.owl", "MI": "http://purl.obolibrary.org/obo/mi.owl", "NCIT": "http://purl.obolibrary.org/obo/ncit.owl", "OGI": "http://purl.obolibrary.org/obo/ogi.owl", "OGG": "http://purl.obolibrary.org/obo/ogg.owl" }, "relevant_publications_doi": [ "10.1093/nar/gkv1068", "10.1093/database/baac023" ], "size": 2 } }