Gene List
This API endpoint handles listing (/genes) and retrieval (/genes/<ID>/) of genes that are contained in the database due to their association to
genetic variants that are involved in at least one oligogenic combination in OLIDA.
GET /api/genecombinations/1268/genes/?format=api
{ "data": [ { "type": "Gene", "id": "ELANE", "attributes": { "go_molecular_function": [ "['endopeptidase activity', 'heparin binding', 'serine-type endopeptidase activity', 'protein binding', 'protease binding', 'transcription corepressor activity', 'peptidase activity', 'cytokine binding']" ], "pathway_id": [ "kegg_path:hsa04613", "kegg_path:hsa05202", "kegg_path:hsa05322", "R-HSA-1442490", "R-HSA-1474228", "R-HSA-1474244", "R-HSA-1592389", "R-HSA-166658", "R-HSA-168249", "R-HSA-168256", "R-HSA-6798695", "R-HSA-6803157", "R-HSA-977606" ], "essential_gene": "Non-essential", "status": "CU", "uniprot_acc": "P08246", "ensembl_id": "None", "entrez_id": "ENSG00000197561", "chromosome_number": "19", "lastmodified": "2024-02-29T15:02:21.056004" }, "relationships": { "variant_set": { "meta": { "count": 1 }, "data": [ { "type": "SmallVariant", "id": "3752" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/ELANE/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/genes/ELANE/variants/?format=api" } }, "genecombination_set": { "meta": { "count": 1 }, "data": [ { "type": "GeneCombination", "id": "1268" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/ELANE/relationships/genecombination_set?format=api", "related": "https://olida.ibsquare.be/api/genes/ELANE/genecombinations/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genes/ELANE/?format=api" } }, { "type": "Gene", "id": "HAX1", "attributes": { "go_molecular_function": [ "['protein N-terminus binding', 'protein binding', 'interleukin-1 binding']" ], "pathway_id": [], "essential_gene": "Non-essential", "status": "CU", "uniprot_acc": "O00165", "ensembl_id": "None", "entrez_id": "ENSG00000143575", "chromosome_number": "1", "lastmodified": "2024-02-29T15:02:21.052152" }, "relationships": { "variant_set": { "meta": { "count": 1 }, "data": [ { "type": "SmallVariant", "id": "3751" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/HAX1/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/genes/HAX1/variants/?format=api" } }, "genecombination_set": { "meta": { "count": 1 }, "data": [ { "type": "GeneCombination", "id": "1268" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/HAX1/relationships/genecombination_set?format=api", "related": "https://olida.ibsquare.be/api/genes/HAX1/genecombinations/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genes/HAX1/?format=api" } } ], "meta": { "database_name": "OLIgogenic diseases DAtabase (OLIDA)", "resource_url": "olida.ibsquare.be", "api_release_year": "2021", "api_developer": [ [ "Arnau Dillen", "arnau.dillen@ulb.ac.be" ], [ "Charlotte Nachtegael", "charlotte.nachtegael@ulb.be" ] ], "api_version": "0.3", "api_maintainers": [ [ "Charlotte Nachtegael", "charlotte.nachtegael@ulb.be" ] ], "api_documentation": [ "olida.ibsquare.be/api/swagger", "olida.ibsquare.be/api/redoc" ], "copyright": "Copyright (c) 2025 · OLIDA All Rights Reserved.", "license": "CC Attribution-NonCommercial 4.0 International License", "ontologies": { "ORDO": "http://bioportal.bioontology.org/ontologies/ORDO", "GENO": "http://purl.obolibrary.org/obo/geno.owl", "MI": "http://purl.obolibrary.org/obo/mi.owl", "NCIT": "http://purl.obolibrary.org/obo/ncit.owl", "OGI": "http://purl.obolibrary.org/obo/ogi.owl", "OGG": "http://purl.obolibrary.org/obo/ogg.owl" }, "relevant_publications_doi": [ "10.1093/nar/gkv1068", "10.1093/database/baac023" ], "size": 2 } }