Gene List
This API endpoint handles listing (/genes) and retrieval (/genes/<ID>/) of genes that are contained in the database due to their association to
genetic variants that are involved in at least one oligogenic combination in OLIDA.
GET /api/genecombinations/1254/genes/?format=api
{ "data": [ { "type": "Gene", "id": "COL27A1", "attributes": { "go_molecular_function": [ "['extracellular matrix structural constituent conferring tensile strength', 'metal ion binding', 'extracellular matrix structural constituent']" ], "pathway_id": [ "kegg_path:hsa04974", "R-HSA-1474244", "R-HSA-1474290", "R-HSA-162582", "R-HSA-1650814", "R-HSA-2022090", "R-HSA-6806834", "R-HSA-8874081", "R-HSA-8875878", "R-HSA-8948216", "R-HSA-9006934" ], "essential_gene": null, "status": "CU", "uniprot_acc": "Q8IZC6", "ensembl_id": "None", "entrez_id": "ENSG00000196739", "chromosome_number": "9", "lastmodified": "2024-02-29T15:02:20.996890" }, "relationships": { "variant_set": { "meta": { "count": 1 }, "data": [ { "type": "SmallVariant", "id": "3706" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/COL27A1/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/genes/COL27A1/variants/?format=api" } }, "genecombination_set": { "meta": { "count": 1 }, "data": [ { "type": "GeneCombination", "id": "1254" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/COL27A1/relationships/genecombination_set?format=api", "related": "https://olida.ibsquare.be/api/genes/COL27A1/genecombinations/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genes/COL27A1/?format=api" } }, { "type": "Gene", "id": "TYRO3", "attributes": { "go_molecular_function": [ "['protein tyrosine kinase activity', 'phosphatidylinositol 3-kinase binding', 'protein serine/threonine/tyrosine kinase activity', 'transmembrane receptor protein tyrosine kinase activity', 'virus receptor activity', 'protein binding', 'ATP binding']" ], "pathway_id": [], "essential_gene": "Non-essential", "status": "CU", "uniprot_acc": "Q06418", "ensembl_id": "None", "entrez_id": "ENSG00000092445", "chromosome_number": "15", "lastmodified": "2021-10-18T11:00:44.874235" }, "relationships": { "variant_set": { "meta": { "count": 3 }, "data": [ { "type": "SmallVariant", "id": "1945" }, { "type": "SmallVariant", "id": "2953" }, { "type": "SmallVariant", "id": "3707" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/TYRO3/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/genes/TYRO3/variants/?format=api" } }, "genecombination_set": { "meta": { "count": 3 }, "data": [ { "type": "GeneCombination", "id": "659" }, { "type": "GeneCombination", "id": "982" }, { "type": "GeneCombination", "id": "1254" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/TYRO3/relationships/genecombination_set?format=api", "related": "https://olida.ibsquare.be/api/genes/TYRO3/genecombinations/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genes/TYRO3/?format=api" } } ], "meta": { "database_name": "OLIgogenic diseases DAtabase (OLIDA)", "resource_url": "olida.ibsquare.be", "api_release_year": "2021", "api_developer": [ [ "Arnau Dillen", "arnau.dillen@ulb.ac.be" ], [ "Charlotte Nachtegael", "charlotte.nachtegael@ulb.be" ] ], "api_version": "0.3", "api_maintainers": [ [ "Charlotte Nachtegael", "charlotte.nachtegael@ulb.be" ] ], "api_documentation": [ "olida.ibsquare.be/api/swagger", "olida.ibsquare.be/api/redoc" ], "copyright": "Copyright (c) 2025 · OLIDA All Rights Reserved.", "license": "CC Attribution-NonCommercial 4.0 International License", "ontologies": { "ORDO": "http://bioportal.bioontology.org/ontologies/ORDO", "GENO": "http://purl.obolibrary.org/obo/geno.owl", "MI": "http://purl.obolibrary.org/obo/mi.owl", "NCIT": "http://purl.obolibrary.org/obo/ncit.owl", "OGI": "http://purl.obolibrary.org/obo/ogi.owl", "OGG": "http://purl.obolibrary.org/obo/ogg.owl" }, "relevant_publications_doi": [ "10.1093/nar/gkv1068", "10.1093/database/baac023" ], "size": 2 } }